Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marielena V. McGuire"'
Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling
Autor:
Guo Fu, Oreste Acuto, Jianfang Hu, Anil Munshi, Vasily Rybakin, Sébastien Vallée, Marielena V. McGuire, Claudia Brockmeyer, Mogjiborahman Salek, John A. H. Hoerter, Nicholas R. J. Gascoigne, Howard S Fox, Karsten Sauer, Yina H. Huang, Jeanette Ampudia, Paul R Fallen
Publikováno v:
Nature immunology
Themis (thymocyte-expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis had high expression in thymocytes between the pre-T cell antigen re
Publikováno v:
Mammalian Genome. 12:664-667
Chromatin remodeling complexes are important factors in the regulation of RNA transcription, DNA replication, recombination, and repair. Two major types of chromatin remodeling enzymes appear to be highly conserved: the ATP-dependent remodeling compl
Autor:
Stella Redpath, Shane Marine, Christina M. Lin, PJ Travers, Bee Cheng Sim, Nicholas R. J. Gascoigne, Nathalie Niederberger, Marielena V. McGuire, M. Anna Zal, S. Munir Alam, Pia P. Yachi, Tomasz Zal
Publikováno v:
Immunologic research. 21(2-3)
The kinetics of the interaction between T cell receptor (TCR) and major histocompatibility complex (MHC) has an important role in determining thymocyte-positive and -negative selection in the thymus, as well as in T cell activation. The alpha chain o