Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mariela A. Blum Murphy"'
Autor:
Brian D. Badgwell, Prajnan Das, Jeannelyn S. Estrella, Timothy E. Newhook, Bruce D. Minsky, Naruhiko Ikoma, Mariela A. Blum Murphy, Jaffer A. Ajani, Paul F. Mansfield, Alisa N. Blumenthaler
Publikováno v:
J Surg Oncol
BACKGROUND AND OBJECTIVES We sought to evaluate the impact of lymphovascular invasion (LVI) and perineural invasion (PNI) on survival outcomes in gastric cancer patients treated with preoperative therapy. METHODS Patients with gastric cancer treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01acbd2bb5545c8ad16615653c919ca1
https://doi.org/10.1002/jso.26367
https://doi.org/10.1002/jso.26367
Autor:
Brian D. Badgwell, Catherine E Devine, Yang Lu, Jane E. Rogers, Ahmed Abdelhakeem, Allison Trail, Naruhiko Ikoma, Tara Sagebiel, Xuemei Wang, Jeannelyn S. Estrella, Madhavi Patnana, Jaffer A. Ajani, Mariela A. Blum Murphy
Publikováno v:
Oncology. 99:659-664
Background: The value of baseline fluorodeoxyglucose-positron emission tomography-computed tomography (PET-CT) remains uncertain once gastroesophageal cancer is metastatic. We hypothesized that assessment of detailed PET-CT parameters (maximum standa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2c6af64351895fe9c007adb5e658d2
https://doi.org/10.1159/000517842
https://doi.org/10.1159/000517842
Autor:
Fang Wang, Minghao Dang, Ruiping Wang, Guang Peng, Ahmed Abdelhakeem, Brian D. Badgwell, Namita Shanbhag, Guangchun Han, Yanshuo Chu, Shuangtao Zhao, Yuanxin Wang, Jaffer A. Ajani, Mingyao Li, Kazuto Harada, George A. Calin, Dapeng Hao, Alexander J. Lazar, Shumei Song, Sinchita Roy-Chowdhuri, Andrew Futreal, Linghua Wang, Jianhua Zhang, Shaojun Zhang, Melissa Pool Pizzi, Ken Chen, Xingzhi Song, Meina Zhao, Jeannelyn S. Estrella, Mariela A. Blum Murphy, Samir M. Hanash, Ghia Tatlonghari, Yang Lu
Publikováno v:
Nat Med
Intratumoral heterogeneity (ITH) is a fundamental property of cancer; however, the origins of ITH remain poorly understood. We performed single-cell transcriptome profiling of peritoneal carcinomatosis (PC) from 15 patients with gastric adenocarcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b1b74394f5cbdc3279d521650b5847
https://doi.org/10.1038/s41591-020-1125-8
https://doi.org/10.1038/s41591-020-1125-8
Autor:
Lu Chen, Xingzhi Song, Mariela A. Blum Murphy, Rebecca E Waters, Guangchun Han, Shumei Song, Jeannelyn S. Estrella, Jaffer A. Ajani, Ju Seog Lee, Qiong Gan, Samir M. Hanash, Linghua Wang, Dapeng Hao, Melissa Pool Pizzi, Jianhua Zhang, Namita Shanbhag, Shaojun Zhang, Manoop S. Bhutani, Siyuan He, Sinchita Roy-Chowdhuri, Guang Peng, Pujun Guan, Jeffrey H. Lee, Yang Lu, Brian Weston, Matheus Sewastjanow-Silva, Ahmed Abdelhakeem, Kazuto Harada, Shuangtao Zhao, Ruiping Wang, George A. Calin
Publikováno v:
Gut. 70:2055-2065
ObjectivePrognosis of patients with advanced oesophagogastric adenocarcinoma (mEGAC) is poor and molecular determinants of shorter or longer overall survivors are lacking. Our objective was to identify molecular features and develop a prognostic mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cebf036264a41ed779b1f37bedd79c
https://doi.org/10.1136/gutjnl-2020-322707
https://doi.org/10.1136/gutjnl-2020-322707
Autor:
Brian D. Badgwell, Mariela A. Blum Murphy, Prajnan Das, Paul F. Mansfield, Bruce D. Minsky, Naruhiko Ikoma, Jeannelyn S. Estrella, Jaffer A. Ajani
Publikováno v:
Journal of Gastrointestinal Surgery. 25:1380-1387
The Cancer Staging Manual, 8th edition, now includes post-neoadjuvant therapy (ypTNM) staging for gastric cancer patients. Our purpose was to determine whether the tumor regression grade (TRG) of the primary tumor is useful for predicting the surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d342341a7bc1ab2a62a8fbead72e48e1
https://doi.org/10.1007/s11605-020-04688-2
https://doi.org/10.1007/s11605-020-04688-2
Autor:
Joseph M. Herman, Mariela A. Blum Murphy, Eugene J. Koay, Jennifer C. Ho, Naruhiko Ikoma, Shalini Moningi, Christopher H. Crane, Paul F. Mansfield, Jaffer A. Ajani, Grace L. Smith, Bruce D. Minsky, Emma B. Holliday, Brian D. Badgwell, Albert C. Koong, Prajnan Das, Sunil Krishnan, Yelin Suh, Cullen M. Taniguchi
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 3, Pp 369-376 (2020)
Advances in Radiation Oncology
Advances in Radiation Oncology
Purpose: Preoperative chemoradiation is being currently evaluated in 2 randomized international trials. However, chemoradiation for gastric cancer can be associated with relatively high rates of acute toxicity. We compared rates of toxicity, toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e64aa12a99b34617a993349cf3fbcfa
http://www.sciencedirect.com/science/article/pii/S2452109419301678
http://www.sciencedirect.com/science/article/pii/S2452109419301678
Autor:
Mariela A. Blum Murphy, Naruhiko Ikoma, Bruce D. Minsky, Prajnan Das, Paul F. Mansfield, Jeannelyn S. Estrella, Brian D. Badgwell, Sinchita Roy-Chowdhuri, Jaffer A. Ajani, Shumei Song, Xuemei Wang
Publikováno v:
Annals of Surgical Oncology. 27:2806-2811
The purpose of this phase I trial is to evaluate the safety and toxicity of laparoscopic hyperthermic intraperitoneal perfusion with chemotherapy (HIPEC), combining mitomycin, cisplatin, and paclitaxel for patients with gastric cancer metastatic to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf0aaa7f634fa3aaf404f12193cc68ee
https://doi.org/10.1245/s10434-020-08226-x
https://doi.org/10.1245/s10434-020-08226-x
Autor:
Michael J. Overman, Ramzi Melhem, Mariela A. Blum-Murphy, Claudia Ramos, Lina Petrosyan, Jack Li, Jessica K Perer, Hui Zou, Ming Wang, Harold M Wright
Publikováno v:
Journal of Clinical Oncology. 41:TPS765-TPS765
TPS765 Background: PT886 is a novel bispecific antibody that targets Claudin 18.2 (CLDN18.2) and CD47. CLDN18.2 is overexpressed in a significant proportion of gastric and pancreatic adenocarcinomas and its restricted expression makes it a promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb37122a64cdcc966546cd063424dca
https://doi.org/10.1200/jco.2023.41.4_suppl.tps765
https://doi.org/10.1200/jco.2023.41.4_suppl.tps765
Autor:
Mariela A. Blum Murphy, Jaffer A. Ajani, Brian Andrew Van Tine, Jeffrey Melson Clarke, Marcus O. Butler, Donald P. Lawrence, Melissa Lynne Johnson, Andres Cervantes, Victor Moreno, David S. Hong, Francine Elizabeth Brophy, Jean-Marc Navenot, Quan Lin, Jose Saro, Elliot Norry
Publikováno v:
Journal of Clinical Oncology. 41:349-349
349 Background: ADP-A2M4CD8 is a specific peptide enhanced affinity receptor mixed CD4+ and CD8+ T-cell therapy targeting the cancer testis antigen MAGE-A4 and modified with addition of a CD8α co-receptor designed to provide additional functionality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72b911a862f26568f30ce89685bc2d4a
https://doi.org/10.1200/jco.2023.41.4_suppl.349
https://doi.org/10.1200/jco.2023.41.4_suppl.349
Autor:
Ken Kato, Jaffer A. Ajani, Yuichiro Doki, Jianming Xu, Lucjan Wyrwicz, Satoru Motoyama, Takashi Ogata, Hisato Kawakami, Chih-Hung Hsu, Antoine Adenis, Farid El Hajbi, Maria Di Bartolomeo, Maria Ignez Freitas Melro Braghiroli, Eva Holtved, Mariela A. Blum Murphy, Apurva Patel, Nan Hu, Yasuhiro Matsumura, Ian Chau, Yuko Kitagawa
Publikováno v:
Journal of Clinical Oncology. 41:290-290
290 Background: NIVO + chemo and NIVO + IPI demonstrated superior overall survival (OS) vs chemo in CheckMate 648 (NCT03143153), leading to approvals in the US, EU, Japan, and other countries. We report longer follow-up results. Methods: Adults with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b5d63143a7ea65a76d07f8728559423
https://doi.org/10.1200/jco.2023.41.4_suppl.290
https://doi.org/10.1200/jco.2023.41.4_suppl.290