Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity

Autor: Alaeddine Djillani, Mariel Pietri, Sébastien Moreno, Catherine Heurteaux, Jean Mazella, Marc Borsotto

Publikováno v: Frontiers in Pharmacology, Vol 8 (2017)

Depression is a devastating mental disorder that affects 20% of the population worldwide. Despite their proven efficacy, antidepressants present a delayed onset of action and serious adverse effects. Seven years ago, we described spadin (PE 12-28) as

Externí odkaz: https://doaj.org/article/82afa037b625468fb2e7f56da6976764

Alexithymie et victimation chronique au sein du couple

Autor: Mariel Pietri, Agnès Bonnet

Publikováno v: Annales Médico-Psychologiques, Revue Psychiatrique
Annales Médico-Psychologiques, Revue Psychiatrique, Elsevier Masson, 2017, 175 (3), pp.223-228. ⟨10.1016/j.amp.2016.06.004⟩

Resume La chronicite des phenomenes de victimation au sein du couple pourrait etre associee a une conduite a risque, le risque d’etre blesse ou tue. L’engagement dans certains types de comportements est en partie maintenu par des facteurs emotion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae9b0b75047a01b5b2ae3c63f440e6f
https://doi.org/10.1016/j.amp.2016.06.004

First evidence of protective effects on stroke recovery and post-stroke depression induced by sortilin-derived peptides

Autor: Jean Mazella, Marc Borsotto, Alaeddine Djillani, Catherine Heurteaux, Mariel Pietri

Publikováno v: Neuropharmacology
Neuropharmacology, Elsevier, 2019, 158, pp.107715. ⟨10.1016/j.neuropharm.2019.107715⟩

Post-stroke depression (PSD) is the most common mood disorder following stroke with high relevance for outcome and survival of patients. The TREK-1 channel represents a crucial target in the pathogenesis of stroke and depression. Spadin and its short

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ecce096f9431e24b76fded446f89dd
https://pubmed.ncbi.nlm.nih.gov/31325429

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

Autor: Tao Sun, Céline S Nicolas, Nikita Lukianets, Mariel Pietri, Laura Frangeul, Michèle Studer, Guillaume Sandoz, Franck Grammont, Denis Jabaudon, Christian Alfano, Kawssar Harb, Elia Magrinelli

Publikováno v: eLife
eLife, 2016, ⟨10.7554/eLife.09531.020⟩
eLife, Vol 5 (2016)
eLife, Vol. 5 (2016) P. e09531
eLife, eLife Sciences Publication, 2016, ⟨10.7554/eLife.09531.020⟩

During cortical development, the identity of major classes of long-distance projection neurons is established by the expression of molecular determinants, which become gradually restricted and mutually exclusive. However, the mechanisms by which proj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd42e32c80ee5b170218162b92b34b4c
https://hal.science/hal-01292321

Differential neuronal plasticity in mouse hippocampus associated with various periods of enriched environment during postnatal development

Autor: Hadi Zarif, Salma Hosseiny, Joëlle Chabry, Mariel Pietri, Alice Guyon, Catherine Heurteaux, Agnès Petit-Paitel

Publikováno v: Brain Structure and Function
Brain Structure and Function, Springer Verlag, 2015, 220 (6), pp.3435-3448. ⟨10.1007/s00429-014-0865-y⟩

Enriched environment (EE) is characterized by improved conditions for enhanced exploration, cognitive activity, social interaction and physical exercise. It has been shown that EE positively regulates the remodeling of neural circuits, memory consoli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa56f514d4b13f78eddd48066d13c939
https://hal.archives-ouvertes.fr/hal-03016570