Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marieke de Kam"'
Publikováno v:
Advances in Pharmacological Sciences, Vol 2012 (2012)
Various 𝛼2,3 subtype selective partial GABA-A agonists are in development to treat anxiety disorders. These compounds are expected to be anxiolytic with fewer undesirable side effects, compared to nonselective GABA-A agonists like benzodiazepines.
Externí odkaz:
https://doaj.org/article/3fba3271ac444816aaf35cd61da630f3
Autor:
Catherine de Cuba, Jules Heuberger, Titia Ruijs, John Hutchison, Jan Bold, Thomas Skjærlund Grønnebæk, Klaus Gjervig Jensen, Eva Chin, Jorge Quiroz, Marieke de Kam, Ingrid Koopmans, Annika de Goede, Thomas Holm Pedersen, Geert Jan Groeneveld
Publikováno v:
Clinical Neurophysiology. 150:e183-e184
Autor:
Ingrid Koopmans, Robert-Jan Doll, Hein van der Wall, Marieke de Kam, Geert Jan Groeneveld, Adam Cohen, Rob Zuiker
Publikováno v:
PLOS ONE. 18:e0278300
Introduction Drivers should be aware of possible impairing effects of alcohol, medicinal substance, or fatigue on driving performance. Such effects are assessed in clinical trials, including a driving task or related psychomotor tasks. However, a cho
Autor:
Catherine de Cuba, Titia Ruijs, Ingrid Koopmans, Marieke de Kam, Geert Jan Groeneveld, Jules Heuberger
Publikováno v:
Clinical Neurophysiology. 141:S79-S80
Autor:
Gabriel E. Jacobs, Joop M. A. van Gerven, Pieter Siebenga, Marieke de Kam, Kawita M. S. Kanhai, Wayne C. Drevets, Paulien Ravenstijn, Luc Van Nueten, Maarten Timmers, Kasper Recourt, Rob Zuiker, Peter de Boer, Jasper van der Aart
Publikováno v:
Journal of Psychopharmacology, 34(9), 1030-1042. SAGE PUBLICATIONS LTD
Background: This is the first report of the pharmacodynamic (PD) effects of the selective, potent and brain-penetrant P2X7 receptor (P2X7R) antagonist JNJ-54175446. Activation of the P2X7R, an adenosine triphosphate-gated ion channel, leads to the pr
Autor:
Federico Bolognani, Matthias Machacek, Annelieke Kruithof, Marieke de Kam, Kirsten Bergmann, Max van Gent, Matthias Moerland, Pascal Crenn, Christian Meyer, Gerard Greig, Pim Gal, Pascal Schulthess
Publikováno v:
Transplantation. 106:S544-S544
Autor:
Titia Ruijs, Jules Heuberger, Ingrid Koopmans, Kaye de Cuba, Marieke de Kam, Geert Jan Groeneveld
Publikováno v:
Clinical Neurophysiology. 141:S140
Publikováno v:
Clinical Neurophysiology. 135:e14-e15
Autor:
Raj Kumar, Karen Broekhuizen, Ingrid M C Kamerling, Marlous R. Dillingh, Jacobus Burggraaf, Wadim M I de Boon, Marieke de Kam, Asger Reinstrup Bihlet, Kim Henriksen, Morten A. Karsdal, Claus Christiansen
There is a need for anti-diabetic agents successfully targeting insulin sensitivity and treating obesity control at the same time. The aim of this first-in-human study was 1) to evaluate safety and tolerability; 2) to evaluate pharmacokinetics and 3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469114c1be95dee71d930c43b4796ece
https://doi.org/10.22541/au.161324382.26126822/v1
https://doi.org/10.22541/au.161324382.26126822/v1
Autor:
Lenneke Schrier, Dimitrios Ziagkos, Michiel J van Esdonk, Justin Jacobse, Stefan Romeijn, Marieke de Kam, Wim Jiskoot, Dirk Jan A.R. Moes, Koen van der Maaden, Joke A. Bouwstra, Robert Rissmann, Anushka Tandon, Gertjan Wolbink, Karien Bloem, Wouter ten Voorde, Floris C. Loeff, Rebecca ten Cate, Matthijs Moerland, Annick de Vries, Jacobus Burggraaf, Hendrika W. Grievink, Theo Rispens
Aim To evaluate feasibility of intradermal (i.d.) adalimumab administration using hollow microneedles, and to compare a single i.d. dose of adalimumab using a hollow microneedle with a single subcutaneous (s.c.) dose using a conventional needle. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c478b91495b6c05652d7c0adc5f1878
https://doi.org/10.22541/au.160133498.87472738
https://doi.org/10.22541/au.160133498.87472738