Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marieke H Heineke"'
Autor:
Joris K Sprokholt, Marieke H Heineke, Tanja M Kaptein, John L van Hamme, Teunis B H Geijtenbeek
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185580 (2017)
Microbial DNA is highly immunostimulatory and is sensed by endosomal pattern recognition receptors after release from internalized microbes. It is unclear how extracellular DNA released from dead microbes is delivered to endosomal PRRs to induce immu
Externí odkaz:
https://doaj.org/article/8f050f44d47b443193734c8e9d96dcb0
Autor:
Marieke H. Heineke, Paula J. Winter, Niels Heemskerk, Suzanne N. Lissenberg-Thunnissen, Marco de Donatis, Dennis Y. Gout, A. Robin Temming, Cornelis W. Tuk, Thies Rösner, Marijn Bögels, Tessa Hellingman, Mandy Gruijs, Marjolein van Egmond, Jantine E. Bakema, Arthur E. H. Bentlage, Gestur Vidarsson, Thomas Valerius
Publikováno v:
Journal of Clinical Investigation, 131(6), 1. The American Society for Clinical Investigation
J Clin Invest
Heemskerk, N, Gruijs, M, Temming, A R, Heineke, M H, Gout, D Y, Hellingman, T, Tuk, C W, Winter, P J, Lissenberg-Thunnissen, S, Bentlage, A E, de Donatis, M, Bögels, M, Rösner, T, Valerius, T, Bakema, J E, Vidarsson, G & van Egmond, M 2021, ' Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity ', Journal of Clinical Investigation, vol. 131, no. 6, e134680 . https://doi.org/10.1172/JCI134680
Journal of Clinical Investigation, 131(6):e134680. The American Society for Clinical Investigation
Journal of clinical investigation, 131(6):e134680. The American Society for Clinical Investigation
J Clin Invest
Heemskerk, N, Gruijs, M, Temming, A R, Heineke, M H, Gout, D Y, Hellingman, T, Tuk, C W, Winter, P J, Lissenberg-Thunnissen, S, Bentlage, A E, de Donatis, M, Bögels, M, Rösner, T, Valerius, T, Bakema, J E, Vidarsson, G & van Egmond, M 2021, ' Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity ', Journal of Clinical Investigation, vol. 131, no. 6, e134680 . https://doi.org/10.1172/JCI134680
Journal of Clinical Investigation, 131(6):e134680. The American Society for Clinical Investigation
Journal of clinical investigation, 131(6):e134680. The American Society for Clinical Investigation
Most clinically used anticancer mAbs are of the IgG isotype, which can eliminate tumor cells through NK cell-mediated antibody-dependent cellular cytotoxicity and macrophage-mediated antibody-dependent phagocytosis. IgG, however, ineffectively recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253c7d45fb6c5b38d74a0986dbf8bca1
https://dspace.library.uu.nl/handle/1874/425229
https://dspace.library.uu.nl/handle/1874/425229
Autor:
Agnès Jamin, Marjolein van Egmond, Sanae Ben Mkaddem, Renato C. Monteiro, Aranka V Ballering, Marieke H. Heineke
Publikováno v:
Heineke, M H, Ballering, A V, Jamin, A, Ben Mkaddem, S, Monteiro, R C & Van Egmond, M 2017, ' New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura) ', Autoimmunity Reviews, vol. 16, no. 12, pp. 1246-1253 . https://doi.org/10.1016/j.autrev.2017.10.009
Immunoglobulin A vasculitis (IgAV), also referred to as Henoch-Schönlein purpura, is the most common form of childhood vasculitis. The pathogenesis of IgAV is still largely unknown. The disease is characterized by IgA1-immune deposits, complement fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa506be7deeb494d8b2810883a0ec192
https://hdl.handle.net/11370/c0c6b3fe-bda7-4806-99a9-cb97a46c5315
https://hdl.handle.net/11370/c0c6b3fe-bda7-4806-99a9-cb97a46c5315
Autor:
Sophie K. Horrevorts, Dorian A. Stolk, Rieneke van de Ven, Myrthe Hulst, Bert van Het Hof, Sanne Duinkerken, Marieke H. Heineke, Wenbin Ma, Sophie A. Dusoswa, Rienk Nieuwland, Juan J. Garcia-Vallejo, Arjan A. van de Loosdrecht, Tanja D. de Gruijl, Sandra J. van Vliet, Yvette van Kooyk
Publikováno v:
Cancers
Cancers, Vol 11, Iss 9, p 1266 (2019)
Cancers, Vol 11, Iss 9, p 1266 (2019)
Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer vaccination for the initiation of anti-tumor T cell responses. An attractive vaccine strategy is in vivo targeting of dendri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1d07d9098995bed67083e9717fc5851e
http://europepmc.org/articles/PMC6769957
http://europepmc.org/articles/PMC6769957
Autor:
Sandra J. van Vliet, Sophie A. Dusoswa, Juan J. Garcia-Vallejo, Rienk Nieuwland, Dorian A. Stolk, Rieneke van de Ven, Sanne Duinkerken, Arjan A. van de Loosdrecht, Bert van het Hof, Sophie K. Horrevorts, Myrthe Hulst, Yvette van Kooyk, Marieke H. Heineke, Wenbin Ma, Tanja D. de Gruijl
Publikováno v:
Cancers, 11(9):1266. Multidisciplinary Digital Publishing Institute (MDPI)
Horrevorts, S K, Stolk, D A, van de Ven, R, Hulst, M, van Het Hof, B, Duinkerken, S, Heineke, M H, Ma, W, Dusoswa, S A, Nieuwland, R, Garcia-Vallejo, J J, van de Loosdrecht, A A, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2019, ' Glycan-modified melanoma-derived apoptotic extracellular vesicles as antigen source for anti-tumor vaccination ', Cancers, vol. 11, no. 9, 1266 . https://doi.org/10.3390/cancers11091266
Cancers
Volume 11
Issue 9
Horrevorts, S K, Stolk, D A, van de Ven, R, Hulst, M, van Het Hof, B, Duinkerken, S, Heineke, M H, Ma, W, Dusoswa, S A, Nieuwland, R, Garcia-Vallejo, J J, van de Loosdrecht, A A, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2019, ' Glycan-modified melanoma-derived apoptotic extracellular vesicles as antigen source for anti-tumor vaccination ', Cancers, vol. 11, no. 9, 1266 . https://doi.org/10.3390/cancers11091266
Cancers
Volume 11
Issue 9
Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer vaccination for the initiation of anti-tumor T cell responses. An attractive vaccine strategy is in vivo targeting of dendri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ff098c35334e614fb922925792d438
https://doi.org/10.3390/cancers11091266
https://doi.org/10.3390/cancers11091266
Autor:
Louise W. Treffers, Michel van Houdt, Christine W. Bruggeman, Marieke H. Heineke, Xi Wen Zhao, Joris van der Heijden, Sietse Q. Nagelkerke, Paul J. J. H. Verkuijlen, Judy Geissler, Suzanne Lissenberg-Thunnissen, Thomas Valerius, Matthias Peipp, Katka Franke, Robin van Bruggen, Taco W. Kuijpers, Marjolein van Egmond, Gestur Vidarsson, Hanke L. Matlung, Timo K. van den Berg
Publikováno v:
Treffers, L W, van Houdt, M, Bruggeman, C W, Heineke, M H, Zhao, X W, van der Heijden, J, Nagelkerke, S Q, Verkuijlen, P J J H, Geissler, J, Lissenberg-Thunnissen, S, Valerius, T, Peipp, M, Franke, K, van Bruggen, R, Kuijpers, T W, van Egmond, M, Vidarsson, G, Matlung, H L & van den Berg, T K 2019, ' FcγRIIIb restricts antibody-dependent destruction of cancer cells by human neutrophils ', Frontiers in Immunology, vol. 10, no. JAN, 03124 . https://doi.org/10.3389/fimmu.2018.03124
Frontiers in Immunology, Vol 9 (2019)
Frontiers in Immunology, 10(JAN):03124
Frontiers in immunology, 9:3124. Frontiers Media S.A.
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2019)
Frontiers in Immunology, 10(JAN):03124
Frontiers in immunology, 9:3124. Frontiers Media S.A.
Frontiers in Immunology
The function of the low-affinity IgG-receptor FcγRIIIb (CD16b), which is uniquely and abundantly expressed on human granulocytes, is not clear. Unlike the other Fcγ receptors (FcγR), it is a glycophosphatidyl inositol (GPI) -anchored molecule and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baccb111f94aec2f7c006f86704d0049
https://research.vumc.nl/en/publications/3a8d4d43-d10c-4e2a-b1fd-20afa6aa4c36
https://research.vumc.nl/en/publications/3a8d4d43-d10c-4e2a-b1fd-20afa6aa4c36
Autor:
Marieke H. Heineke, Melissa Newling, Willianne Hoepel, Lisa T. C. Vogelpoel, Taco W. Kuijpers, Tim Beaumont, Martien L. Kapsenberg, Esther W. Taanman-Kueter, Marjolein van Egmond, Johan A. van Burgsteden, Esther C. de Jong, Dominique Baeten, Jeroen den Dunnen, Dirk Eggink
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 48(11), 1796-1809. Wiley-VCH Verlag
Newling, M, Hoepel, W, Vogelpoel, L T C, Heineke, M H, van Burgsteden, J A, Taanman-Kueter, E W M, Eggink, D, Kuijpers, T W, Beaumont, T, van Egmond, M, Kapsenberg, M L, Baeten, D L P, den Dunnen, J & Jong, E C D 2018, ' Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells ', European Journal of Immunology, vol. 48, no. 11, pp. 1796-1809 . https://doi.org/10.1002/eji.201847615
European journal of immunology, 48(11), 1796-1809. Wiley-VCH Verlag
European Journal of Immunology, 48(11), 1796-1809. Wiley-VCH Verlag
Newling, M, Hoepel, W, Vogelpoel, L T C, Heineke, M H, van Burgsteden, J A, Taanman-Kueter, E W M, Eggink, D, Kuijpers, T W, Beaumont, T, van Egmond, M, Kapsenberg, M L, Baeten, D L P, den Dunnen, J & Jong, E C D 2018, ' Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells ', European Journal of Immunology, vol. 48, no. 11, pp. 1796-1809 . https://doi.org/10.1002/eji.201847615
European journal of immunology, 48(11), 1796-1809. Wiley-VCH Verlag
Type I and type III interferons (IFNs) are fundamental for antiviral immunity, but prolonged expression is also detrimental to the host. Therefore, upon viral infection high levels of type I and III IFNs are followed by a strong and rapid decline. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989b73e7ec65b542ecdd928395fcdaa0
https://pubmed.ncbi.nlm.nih.gov/30184252
https://pubmed.ncbi.nlm.nih.gov/30184252
Publikováno v:
Immunological Reviews, 268(1), 123-138. Wiley-Blackwell
Aleyd, E, Heineke, M H & van Egmond, M 2015, ' The era of the immunoglobulin A Fc receptor FcRI; its function and potential as target in disease ', Immunological Reviews, vol. 268, no. 1, pp. 123-138 . https://doi.org/10.1111/imr.12337
Aleyd, E, Heineke, M H & van Egmond, M 2015, ' The era of the immunoglobulin A Fc receptor FcRI; its function and potential as target in disease ', Immunological Reviews, vol. 268, no. 1, pp. 123-138 . https://doi.org/10.1111/imr.12337
Immunoglobulin A (IgA) is the most prevalent antibody at mucosal sites, and has an important role in defense by preventing invasion of pathogens. Traditionally, IgA has been thought of as a non-inflammatory antibody that helps to maintain homeostasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71c75d870f17271903728b1ae764ea1
https://doi.org/10.1111/imr.12337
https://doi.org/10.1111/imr.12337
Autor:
Tanja M. Kaptein, John L. van Hamme, Teunis B. H. Geijtenbeek, Joris K. Sprokholt, Marieke H. Heineke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0185580 (2017)
PLoS ONE, 12(10). Public Library of Science
Sprokholt, J K, Heineke, M H, Kaptein, T M, van Hamme, J L & Geijtenbeek, T B H 2017, ' DCs facilitate B cell responses against microbial DNA via DC-SIGN ', PLoS ONE, vol. 12, no. 10, pp. e0185580 . https://doi.org/10.1371/journal.pone.0185580
PLOS ONE
PLoS ONE, Vol 12, Iss 10, p e0185580 (2017)
PLoS ONE, 12(10). Public Library of Science
Sprokholt, J K, Heineke, M H, Kaptein, T M, van Hamme, J L & Geijtenbeek, T B H 2017, ' DCs facilitate B cell responses against microbial DNA via DC-SIGN ', PLoS ONE, vol. 12, no. 10, pp. e0185580 . https://doi.org/10.1371/journal.pone.0185580
PLOS ONE
Microbial DNA is highly immunostimulatory and is sensed by endosomal pattern recognition receptors after release from internalized microbes. It is unclear how extracellular DNA released from dead microbes is delivered to endosomal PRRs to induce immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0f42f0baa173847c464a76abaad06a
http://europepmc.org/articles/PMC5627929
http://europepmc.org/articles/PMC5627929
Publikováno v:
Heineke, M H & van Egmond, M 2017, ' Immunoglobulin A: magic bullet or Trojan horse? ', European Journal of Clinical Investigation, vol. 47, no. 2, pp. 184-192 . https://doi.org/10.1111/eci.12716
European Journal of Clinical Investigation, 47(2), 184-192
European Journal of Clinical Investigation, 47(2), 184-192
Neutrophils participate in the first line of defense by executing several killing mechanisms, including phagocytosis, degranulation and the release of neutrophil extracellular traps. Additionally, they can orchestrate the adaptive immune system by se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8ec153cbb88535cb69679391f73bb4
https://research.vumc.nl/en/publications/c115b1e4-471a-4f82-b4b5-69342e14f363
https://research.vumc.nl/en/publications/c115b1e4-471a-4f82-b4b5-69342e14f363