Výsledky vyhledávání - "Marieke C Verweij"

Akademický článek

Quantitative membrane proteomics reveals a role for tetraspanin enriched microdomains during entry of human cytomegalovirus.

Autor: Kasinath Viswanathan, Marieke C Verweij, Nessy John, Daniel Malouli, Klaus Früh

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0187899 (2017)

Human cytomegalovirus (HCMV) depends on and modulates multiple host cell membrane proteins during each stage of the viral life cycle. To gain a global view of the impact of HCMV-infection on membrane proteins, we analyzed HCMV-induced changes in the

Externí odkaz: https://doaj.org/article/43b053a6092f4287bfa6a1ef277e3d8a

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Akademický článek

Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus.

Autor: Elizabeth R Sturgill, Daniel Malouli, Scott G Hansen, Benjamin J Burwitz, Seongkyung Seo, Christine L Schneider, Jennie L Womack, Marieke C Verweij, Abigail B Ventura, Amruta Bhusari, Krystal M Jeffries, Alfred W Legasse, Michael K Axthelm, Amy W Hudson, Jonah B Sacha, Louis J Picker, Klaus Früh

Publikováno v: PLoS Pathogens, Vol 12, Iss 8, p e1005868 (2016)

The natural killer cell receptor NKG2D activates NK cells by engaging one of several ligands (NKG2DLs) belonging to either the MIC or ULBP families. Human cytomegalovirus (HCMV) UL16 and UL142 counteract this activation by retaining NKG2DLs and US18

Externí odkaz: https://doaj.org/article/ab867361cfd74334a156f85967627cb8

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Akademický článek

Varicella Viruses Inhibit Interferon-Stimulated JAK-STAT Signaling through Multiple Mechanisms.

Autor: Marieke C Verweij, Mary Wellish, Travis Whitmer, Daniel Malouli, Martin Lapel, Stipan Jonjić, Juergen G Haas, Victor R DeFilippis, Ravi Mahalingam, Klaus Früh

Publikováno v: PLoS Pathogens, Vol 11, Iss 5, p e1004901 (2015)

Varicella zoster virus (VZV) causes chickenpox in humans and, subsequently, establishes latency in the sensory ganglia from where it reactivates to cause herpes zoster. Infection of rhesus macaques with simian varicella virus (SVV) recapitulates VZV

Externí odkaz: https://doaj.org/article/444edbfbf34e42c982d6f8b051d4d9d0

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Akademický článek

Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution.

Autor: Marieke C Verweij, Daniëlle Horst, Bryan D Griffin, Rutger D Luteijn, Andrew J Davison, Maaike E Ressing, Emmanuel J H J Wiertz

Publikováno v: PLoS Pathogens, Vol 11, Iss 4, p e1004743 (2015)

Herpesviruses are large DNA viruses that are highly abundant within their host populations. Even in the presence of a healthy immune system, these viruses manage to cause lifelong infections. This persistence is partially mediated by the virus enteri

Externí odkaz: https://doaj.org/article/53438da65fdd4d49ba4bffa4d8db3293

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Harnessing the unique immune biology of cytomegalovirus for cancer immunotherapy

Publikováno v: The Journal of Immunology. 208:66.15-66.15

Pre-clinical models in non-human primates demonstrate that cytomegalovirus (CMV)-vectored vaccines are unique in their ability to elicit and indefinitely maintain high frequencies of polyfunctional effector memory T cells to heterologous pathogen ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddc431beb311d5be4d4e40010cc5210c
https://doi.org/10.4049/jimmunol.208.supp.66.15

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Akademický článek

Exploitation of herpesvirus immune evasion strategies to modify the immunogenicity of human mesenchymal stem cell transplants.

Autor: Anabel S de la Garza-Rodea, Marieke C Verweij, Hester Boersma, Ietje van der Velde-van Dijke, Antoine A F de Vries, Rob C Hoeben, Dirk W van Bekkum, Emmanuel J H J Wiertz, Shoshan Knaän-Shanzer

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e14493 (2011)

BackgroundMesenchymal stem cells (MSCs) are multipotent cells residing in the connective tissue of many organs and holding great potential for tissue repair. In culture, human MSCs (hMSCs) are capable of extensive proliferation without showing chromo

Externí odkaz: https://doaj.org/article/1ec215d4b23146efaeecfc7cbb4fdc57

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Akademický článek

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP.

Publikováno v: PLoS Pathogens, Vol 4, Iss 5, p e1000080 (2008)

Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell. The

Externí odkaz: https://doaj.org/article/81655c8859bb45398e9374c1f1a2d239

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Transmembrane regions of bovine herpesvirus 1-encoded UL49.5 and glycoprotein M regulate complex maturation and ER-Golgi trafficking

Autor: Andrea D. Lipińska, Krystyna Bieńkowska-Szewczyk, Małgorzata Graul, Marieke C. Verweij, Mathias Ackermann, Emmanuel J. H. J. Wiertz, Michał Rychłowski, Kurt Tobler, Edyta Kisielnicka

Publikováno v: Journal of General Virology, 100(3), 497. Society for General Microbiology

Bovine herpesvirus 1 (BoHV-1)-encoded UL49.5 (a homologue of herpesvirus glycoprotein N) can combine different functions, regulated by complex formation with viral glycoprotein M (gM). We aimed to identify the mechanisms governing the immunomodulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66ec36169c8f9a3cf97e1159ee9c9d8
https://doi.org/10.5167/uzh-178886

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The ORF61 Protein Encoded by Simian Varicella Virus and Varicella-Zoster Virus Inhibits NF-κB Signaling by Interfering with IκBα Degradation

Autor: Travis Whitmer, Klaus Früh, Victor R. DeFilippis, Daniel Malouli, Marieke C. Verweij, Luke S. Uebelhoer

Publikováno v: Journal of Virology. 89:8687-8700

Varicella-zoster virus (VZV) causes chickenpox upon primary infection and establishes latency in ganglia. Reactivation from latency causes herpes zoster, which may be complicated by postherpetic neuralgia. Innate immunity mediated by interferon and p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522e3c6aa5404203eb58268731afb562
https://doi.org/10.1128/jvi.01149-15

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