Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marieke B A C, Lamers"'
Autor:
David F Fischer, Sipke Dijkstra, Kimberly Lo, Johnny Suijker, Ana C P Correia, Patricia Naud, Martin Poirier, Michela A Tessari, Ivette Boogaard, Geraldine Flynn, Mijke Visser, Marieke B A C Lamers, George McAllister, Ignacio Munoz-Sanjuan, Douglas Macdonald
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266812 (2022)
Huntington's disease (HD) is caused by an expansion of the CAG trinucleotide repeat domain in the huntingtin gene that results in expression of a mutant huntingtin protein (mHTT) containing an expanded polyglutamine tract in the amino terminus. A num
Externí odkaz:
https://doaj.org/article/d40329dcbdbd4ce6b214f506ecdfe85c
Autor:
Douglas Macdonald, Michela A Tessari, Ivette Boogaard, Melanie Smith, Kristiina Pulli, Agnieszka Szynol, Faywell Albertus, Marieke B A C Lamers, Sipke Dijkstra, Daniel Kordt, Wolfgang Reindl, Frank Herrmann, George McAllister, David F Fischer, Ignacio Munoz-Sanjuan
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96854 (2014)
The expansion of a CAG trinucleotide repeat in the huntingtin gene, which produces huntingtin protein with an expanded polyglutamine tract, is the cause of Huntington's disease (HD). Recent studies have reported that RNAi suppression of polyglutamine
Externí odkaz:
https://doaj.org/article/655c74cb49f44a9da8ae9d1d8e16f626
Autor:
Gary, Tresadern, Ingrid, Velter, Andrés A, Trabanco, Frans, Van den Keybus, Gregor J, Macdonald, Marijke V F, Somers, Greet, Vanhoof, Philip M, Leonard, Marieke B A C, Lamers, Yves E M, Van Roosbroeck, Peter J J A, Buijnsters
Publikováno v:
Journal of medicinal chemistry. 63(21)
We describe the hit-to-lead exploration of a [1,2,4]triazolo[1,5
Autor:
Jan van Deursen, Joseph H.E.Th. Meuwissen, Marieke B. A. C. Lamers, Hella C. W. Fries, T. Ponnudurai
Publikováno v:
Experimental parasitology. 71(2)
Synthesis of the 25-kDa protein in the early midgut stages of Plasmodium falciparum was studied, using metabolic inhibitors (colchicine and actinomycin D) and pulse-labeling experiments. Experiments with colchicine showed that, immediately after indu
Autor:
Mari A. Smits, Joseph H.E.Th. Meuwissen, Hella C. W. Fries, T. Ponnudurai, Marieke B. A. C. Lamers
Publikováno v:
Parasite Immunology. 11:31-45
A sexual stage-specific protein of Plasmodium falciparum with a Mr of 25,000 is one of the target antigens of transmission-blocking antibodies. The contributions of tertiary structure and post-translational modifications (glycosylation and acylation)