Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Marie-line Peyot"'
Autor:
Abel Oppong, Yat Hei Leung, Anindya Ghosh, Marie-Line Peyot, Marilène Paquet, Carlos Morales, Hugh J. Clarke, Fahd Al-Mulla, Alexandre Boyer, S. R. Murthy Madiraju, Derek Boerboom, Cristian O'Flaherty, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102063- (2024)
Objectives: Obesity, diabetes and high-calorie diets are associated with defective sperm function and lowered male fertility. Mature spermatozoa primarily use fructose and glucose, and glucose and glycerol metabolism are important for sperm function.
Externí odkaz:
https://doaj.org/article/315c683a57974e74b09d44fa08f9ae3d
Autor:
Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, Isabelle Chenier, Yat Hei Leung, Anindya Ghosh, Abel Oppong, Elite Possik, Yves Mugabo, Rasheed Ahmad, Robert Sladek, S.R. Murthy Madiraju, Fahd Al-Mulla, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101609- (2022)
Objective: Glycerol-3-phosphate (Gro3P) phosphatase (G3PP) hydrolyzes Gro3P to glycerol that exits the cell, thereby operating a “glycerol shunt”, a metabolic pathway that we identified recently in mammalian cells. We have investigated the role o
Externí odkaz:
https://doaj.org/article/ef4e4aa106094673b2a836cb280c8599
Autor:
Anfal Al-Mass, Pegah Poursharifi, Marie-Line Peyot, Roxane Lussier, Emily J. Levens, Julian Guida, Yves Mugabo, Elite Possik, Rasheed Ahmad, Fahd Al-Mulla, Robert Sladek, S.R.Murthy Madiraju, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101471- (2022)
Objective: The recently identified glycerol-3-phosphate (Gro3P) phosphatase (G3PP) in mammalian cells, encoded by the PGP gene, was shown to regulate glucose, lipid and energy metabolism by hydrolyzing Gro3P and to control glucose-stimulated insulin
Externí odkaz:
https://doaj.org/article/a0ad8776085242cfa158276b9c6297e7
Autor:
Elite Possik, Anfal Al-Mass, Marie-Line Peyot, Rasheed Ahmad, Fahd Al-Mulla, S. R. Murthy Madiraju, Marc Prentki
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Cardiometabolic diseases, including type 2 diabetes, obesity and non-alcoholic fatty liver disease, have enormous impact on modern societies worldwide. Excess nutritional burden and nutri-stress together with sedentary lifestyles lead to these diseas
Externí odkaz:
https://doaj.org/article/3976edef258f41cfaceb22b4353f8d6e
Autor:
Pegah Poursharifi, Camille Attané, Yves Mugabo, Anfal Al-Mass, Anindya Ghosh, Clémence Schmitt, Shangang Zhao, Julian Guida, Roxane Lussier, Heidi Erb, Isabelle Chenier, Marie-Line Peyot, Erik Joly, Christophe Noll, André C. Carpentier, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Enhanced energy expenditure in brown (BAT) and white adipose tissues (WAT) can be therapeutic against metabolic diseases. We examined the thermogenic role of adipose α/β-hydrolase domain 6 (ABHD6), which hydrolyzes monoacylglycerol (MAG), by employ
Externí odkaz:
https://doaj.org/article/e11e5cce8e0b4e328113e9c46cedfd1c
Autor:
Anna Motterle, Sonia Gattesco, Marie-Line Peyot, Jonathan Lou S. Esguerra, Ana Gomez-Ruiz, D. Ross Laybutt, Patrick Gilon, Frédéric Burdet, Mark Ibberson, Lena Eliasson, Marc Prentki, Romano Regazzi
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1407-1418 (2017)
Objective: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes dev
Externí odkaz:
https://doaj.org/article/3b8e45242e6146db91dafa93326fa629
Autor:
Alexandre Fisette, Stephanie Tobin, Léa Décarie-Spain, Khalil Bouyakdan, Marie-Line Peyot, S.R. Murthy Madiraju, Marc Prentki, Stephanie Fulton, Thierry Alquier
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1217-1226 (2016)
Summary: α/β-Hydrolase domain 6 (ABHD6) is a monoacylglycerol hydrolase that degrades the endocannabinoid 2-arachidonoylglycerol (2-AG). Although complete or peripheral ABHD6 loss of function is protective against diet-induced obesity and insulin r
Externí odkaz:
https://doaj.org/article/38c0435357f247599bf5d59aad540d0a
Autor:
Shangang Zhao, Yves Mugabo, Gwynne Ballentine, Camille Attane, Jose Iglesias, Pegah Poursharifi, Dongwei Zhang, Thuy Anne Nguyen, Heidi Erb, Raphael Prentki, Marie-Line Peyot, Erik Joly, Stephanie Tobin, Stephanie Fulton, J. Mark Brown, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2872-2888 (2016)
Suppression of α/β-domain hydrolase-6 (ABHD6), a monoacylglycerol (MAG) hydrolase, promotes glucose-stimulated insulin secretion by pancreatic β cells. We report here that high-fat-diet-fed ABHD6-KO mice show modestly reduced food intake, decrease
Externí odkaz:
https://doaj.org/article/84a1d24e99c3458a8ee984390c17eca2
Autor:
Shangang Zhao, Pegah Poursharifi, Yves Mugabo, Emily J. Levens, Kevin Vivot, Camille Attane, Jose Iglesias, Marie-line Peyot, Erik Joly, S.R. Murthy Madiraju, Marc Prentki
Publikováno v:
Molecular Metabolism, Vol 4, Iss 12, Pp 940-950 (2015)
Objective: α/β-Hydrolase domain-6 (ABHD6) is a newly identified monoacylglycerol (MAG) lipase. We recently reported that it negatively regulates glucose stimulated insulin secretion (GSIS) in the β cells by hydrolyzing lipolysis-derived MAG that a
Externí odkaz:
https://doaj.org/article/e5610cda190f46468b9fa1ed0a75430a
Autor:
Émilie Pepin, Anfal Al-Mass, Camille Attané, Kezhuo Zhang, Julien Lamontagne, Roxane Lussier, S R Murthy Madiraju, Erik Joly, Neil B Ruderman, Robert Sladek, Marc Prentki, Marie-Line Peyot
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153017 (2016)
Diet induced obese (DIO) mice can be stratified according to their weight gain in response to high fat diet as low responders (LDR) and high responders (HDR). This allows the study of β-cell failure and the transitions to prediabetes (LDR) and early
Externí odkaz:
https://doaj.org/article/a816a82e402c4a1b82063292ec35e8b2