Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marie-Therese Schermeyer"'
Autor:
Niels Krausch, Lucas Kaspersetz, Rogelio Diego Gaytán-Castro, Marie-Therese Schermeyer, Alvaro R. Lara, Guillermo Gosset, Mariano Nicolas Cruz Bournazou, Peter Neubauer
Publikováno v:
Bioengineering, Vol 10, Iss 7, p 808 (2023)
The bacterium Escherichia coli is a widely used organism in biotechnology. For high space-time yields, glucose-limited fed-batch technology is the industry standard; this is because an overflow metabolism of acetate occurs at high glucose concentrati
Externí odkaz:
https://doaj.org/article/8ed71c4103394cf8b278a02cd9b685d3
Autor:
Neubauer, Niels Krausch, Lucas Kaspersetz, Rogelio Diego Gaytán-Castro, Marie-Therese Schermeyer, Alvaro R. Lara, Guillermo Gosset, Mariano Nicolas Cruz Bournazou, Peter
Publikováno v:
Bioengineering; Volume 10; Issue 7; Pages: 808
The bacterium Escherichia coli is a widely used organism in biotechnology. For high space-time yields, glucose-limited fed-batch technology is the industry standard; this is because an overflow metabolism of acetate occurs at high glucose concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::95be9cb80215bd5a993a27d8e062cdc3
Autor:
Nghia Duong-Trung, Stefan Born, Jong Woo Kim, Marie-Therese Schermeyer, Katharina Paulick, Maxim Borisyak, Mariano Nicolas Cruz-Bournazou, Thorben Werner, Randolf Scholz, Lars Schmidt-Thieme, Peter Neubauer, Ernesto Martinez
Publikováno v:
Biochemical Engineering Journal. 190:108764
Machine learning (ML) is becoming increasingly crucial in many fields of engineering but has not yet played out its full potential in bioprocess engineering. While experimentation has been accelerated by increasing levels of lab automation, experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaeaaced71b87984a6b2ada022a59c6
https://doi.org/10.1016/j.bej.2022.108764
https://doi.org/10.1016/j.bej.2022.108764
Autor:
Hannah Burghardt, Jürgen Hubbuch, Cathrin Dürr, Marie-Therese Schermeyer, Pascal Baumann, Jonas Gärtner
Publikováno v:
International Journal of Pharmaceutics. 531:360-371
Solution stability attributes are one of the key parameters within the production and launching phase of new biopharmaceuticals. Instabilities of active biological compounds can reduce the yield of biopharmaceutical productions, and may induce undesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92527f0e824ca255389aab863bbdfd2
https://doi.org/10.1016/j.ijpharm.2017.08.068
https://doi.org/10.1016/j.ijpharm.2017.08.068
Publikováno v:
mAbs
mAbs 9 (2017) 7
mAbs, 9(7), 1169-1185
mAbs 9 (2017) 7
mAbs, 9(7), 1169-1185
High protein titers are gaining importance in biopharmaceutical industry. A major challenge in the development of highly concentrated mAb solutions is their long-term stability and often incalculable viscosity. The complexity of the molecule itself,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21d2f93faf2e8df10f34e7852c1cb30
http://europepmc.org/articles/PMC5627599
http://europepmc.org/articles/PMC5627599
Autor:
Mathias Göbel, Marie-Therese Schermeyer, Katharina Christin Bauer, Marie-Luise Schwab, Jürgen Hubbuch
Publikováno v:
International Journal of Pharmaceutics. 511:276-287
The colloidal stability of a protein solution during downstream processing, formulation, and storage is a key issue for the biopharmaceutical production process. Thus, knowledge about colloidal solution characteristics, such as the tendency to form a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5a276007ad5e83495ccc2d64bbd126
https://doi.org/10.1016/j.ijpharm.2016.07.007
https://doi.org/10.1016/j.ijpharm.2016.07.007
Autor:
Carsten P. Radtke, Jürgen Hubbuch, Jacqueline Göpper, Marie-Therese Schermeyer, Yün Claudia Zhai
Publikováno v:
Engineering in Life Sciences. 16:515-524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d87871d21a47092dada4795fb4c0b7b3
https://doi.org/10.1002/elsc.201500185
https://doi.org/10.1002/elsc.201500185
Autor:
Claude Oelschlaeger, Jürgen Hubbuch, Katharina Christin Bauer, Marie-Therese Schermeyer, Heike Sigloch
Publikováno v:
Biotechnology and Bioengineering. 113:576-587
This study aims at defining rheological parameters for the characterization of highly concentrated protein solutions. As a basis for comparing rheological behavior with protein solution characteristics the protein phase behavior of Lysozyme from chic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3020965162a63d1f596d6272753ec4f4
https://doi.org/10.1002/bit.25834
https://doi.org/10.1002/bit.25834
Autor:
Marie-Therese, Schermeyer, Heike, Sigloch, Katharina C, Bauer, Claude, Oelschlaeger, Jürgen, Hubbuch
Publikováno v:
Biotechnology and bioengineering. 113(3)
This study aims at defining rheological parameters for the characterization of highly concentrated protein solutions. As a basis for comparing rheological behavior with protein solution characteristics the protein phase behavior of Lysozyme from chic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d62b4075b40b0c427d829c98f227436c
https://pubmed.ncbi.nlm.nih.gov/26375304
https://pubmed.ncbi.nlm.nih.gov/26375304