Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie-Sophie Noël-Hudson"'
Autor:
Mahamadou Tandia, Mélanie Polrot, Dora Amor, Marie-Sophie Noël-Hudson, Chadi Abbara, Patrick Gonin, Laurence Bonhomme-Faivre
Publikováno v:
International Journal of Innovative Research in Medical Science. 5:261-267
Overexpression of P-glycoprotein (P-gp) is associated with multidrug resistance. Since sorafenib (NEXAVAR®) is a P-gp (an efflux protein of ATP-binding cassette family) substrate, we tested whether bevacizumab (AVASTIN®), a monoclonal antibody dire
Autor:
Marie-Sophie Noël-Hudson, Jean-meidi Alili, Laurence Bonhomme-Faivre, Patrick Gonin, Mahamadou Tandia, Dora Amor, Mélanie Polrot, Farah Ayadi
Publikováno v:
Le Pharmacien Hospitalier et Clinicien. 54:81
Introduction Le traitement des cancers constitue un probleme de sante publique et fait appel differentes strategies therapeutiques, cependant l’intervention de transporteurs membranaires d’efflux, comme la P-glycoproteine (P-gp) joue un role impo
Autor:
Marie-Sophie Noël-Hudson, Ludovic Bigot, Mélanie Polrot, Diane Goéré, Valérie Boige, Laurence Bonhomme-Faivre, Céline Chu, Robert Farinotti, Patrick Gonin, Sylvie Marion
Publikováno v:
Fundamental & Clinical Pharmacology. 27:434-442
KRAS mutation is a negative predictive prognostic factor during metastatic colorectal cancer treatment with antiepidermal growth factor receptor antibodies. For affected patients, new therapeutics must be explored. Our objective was to study efficacy
Autor:
Sophie Gil, Robert Farinotti, Marie-Sophie Noël-Hudson, F. Forestier, Jean Guibourdenche, Laurent Gavard, Delphine Beghin
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 152:55-59
Objectives The distribution of drugs to the maternal–fetal interface is influenced by the expression of various efflux transporters. Among these transporters, P-glycoprotein (P-gp) is responsible for the efflux of a great number of drugs such as pr
Autor:
Nesrine Benfares, Virginie Belotte, Sédami Gnidehou, Martin Schlumberger, Alain Virion, Jean-Christophe Sabourin, Stanislas Morand, Renée Ohayon, Jean-Michel Bidart, Marie-Sophie Noël-Hudson, Corinne Dupuy, Diane Agnandji, Bernard Caillou, Monique Talbot, Rabii Ameziane El Hassani, Jacques Kaniewski
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G933-G942
The dual oxidase (Duox)2 flavoprotein is strongly expressed in the thyroid gland, where it plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with H2O2. DUOX2 mRNA was recently detected by RT-PCR and in-situ hybri
Autor:
Danielle Dème, Corinne Dupuy, Marie-Sophie Noël-Hudson, Renée Ohayon, Alexander Valent, Alain Virion
Publikováno v:
Journal of Biological Chemistry. 274:37265-37269
Hydrogen peroxide is the final electron acceptor for the biosynthesis of thyroid hormone catalyzed by thyroperoxidase at the apical surface of thyrocytes. Pig and human thyroid plasma membrane contain a Ca2+-dependent NAD(P)H oxidase that generates H
Autor:
Sédami Gnidehou, Alphonse Sezan, Françoise Courtin, Bernard Caillou, Monique Talbot, Corinne Dupuy, Marie-Sophie Noël-Hudson, Diane Agnangji, Alain Virion, Renée Ohayon, Stanislas Morand, Jacques Kaniewski
Publikováno v:
The FASEB Journal. 18:1574-1576
In the thyroid, iodotyrosine dehalogenase acts on the mono and diiodotyrosines released during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. It has been reported that the deiodination of io
Autor:
Alain Virion, Stanislas Morand, Khalid Lalaoui, Jean-Luc Boucher, Yves-Michel Frapart, Jacques Francon, Diane Agnandji, Corinne Dupuy, Daphné Apostolou, Renée Ohayon, Sédami Gnidehou, Rabii Ameziane-El-Hassani, Marie-Sophie Noël-Hudson
Publikováno v:
The Journal of biological chemistry. 280(34)
Duox2 (and probably Duox1) is a glycoflavoprotein involved in thyroid hormone biosynthesis, as the thyroid H2O2 generator functionally associated with Tpo (thyroperoxidase). So far, because of the impairment of maturation and of the targeting process
Autor:
Sédami Gnidehou, Ludovic Lacroix, Alphonse Sezan, Renée Ohayon, Marie-Sophie Noël-Hudson, Stanislas Morand, Jacques Francon, Françoise Courtin, Alain Virion, Corinne Dupuy
Publikováno v:
Thyroid; Aug2006, Vol. 16 Issue 8, p715-724, 10p
Autor:
Chu, Céline1, Noël‐Hudson, Marie‐Sophie2, Boige, Valérie3, Goéré, Diane3, Marion, Sylvie4, Polrot, Mélanie5, Bigot, Ludovic6, Gonin, Patrick5, Farinotti, Robert2, Bonhomme‐Faivre, Laurence1
Publikováno v:
Fundamental & Clinical Pharmacology. Aug2013, Vol. 27 Issue 4, p434-442. 9p. 3 Charts, 2 Graphs.