Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marie-Rose van Schravendijk"'
Autor:
John E. Coligan, T H Hansen, Stanley G. Nathenson, J. Scott Cairns, William E. Biddison, Gertrude M. Pfaffenbach, Marie Rose van Schravendijk, Fritz H. Bach, Richard A. Zeff
Publikováno v:
Paradoxes in Immunology ISBN: 9780429286353
Paradoxes in Immunology
Paradoxes in Immunology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763321d37d0f349100158846a6ed590f
https://doi.org/10.1201/9780429286353-25
https://doi.org/10.1201/9780429286353-25
Autor:
Selvi Pradeepan, Chet Metcalf, Brendan F. Boyce, Shuangying Liu, Manfred Weigele, Surinder S. Narula, Regine S. Bohacek, Lianping Xing, Raji Sundaramoorthi, Jeff Keats, Julie Bogus, Jennifer Saltmarsh, Yihan Wang, Scott Wardwell, Mary K. Ram, David C. Dalgarno, John Iuliucci, Susan Adams, Guru Paramanathan, Shuenn Liou, Marie Rose van Schravendijk, Anne Dilauro, Sonya Roeloffzen, T. Keenan, William C. Shakespeare, Tomi K. Sawyer
Publikováno v:
Chemical Biology & Drug Design. 71:97-105
Targeted disruption of the pp60(src) (Src) gene has implicated this tyrosine kinase in osteoclast-mediated bone resorption and as a therapeutic target for the treatment of osteoporosis and other bone-related diseases. Here, we describe structure acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcdeae0a92758c4ad04f2c1f5760a13
https://doi.org/10.1111/j.1747-0285.2007.00615.x
https://doi.org/10.1111/j.1747-0285.2007.00615.x
Autor:
Carl T. Rollins, Terence P. Keenan, Marie Rose van Schravendijk, Tim Clackson, Marcos Hatada, David Yaeger, Michael Z. Gilman, Dennis A. Holt, Victor M. Rivera, Lawrence J. Andrade, Derek N. Woolfson, Susan Adams
Publikováno v:
Proceedings of the National Academy of Sciences. 97:7096-7101
Chemically induced dimerization provides a general way to gain control over intracellular processes. Typically, FK506-binding protein (FKBP) domains are fused to a signaling domain of interest, allowing crosslinking to be initiated by addition of a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3635e4e24a7f917d014ff5f49461f0
https://doi.org/10.1073/pnas.100101997
https://doi.org/10.1073/pnas.100101997
Publikováno v:
Protein Expression and Purification. 17:305-311
The A(280)/A(260) ratio of a purified protein is frequently used as an indication of the purity of the preparation with respect to nucleic acids. We show here that for low-molecular-weight recombinant proteins purified from Escherichia coli, a low A(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4f19afb8707784d81d12a5c314a94f
https://doi.org/10.1006/prep.1999.1145
https://doi.org/10.1006/prep.1999.1145
Autor:
Ian A. MacNeil, Berkley A. Lynch, Marie Rose van Schravendijk, Richard J. Rickles, Minor Charles A, Kara A. Loiacono, Mary K. Ram, T. B. Phillips, Susan Adams, Raji Sundaramoorthi, Dennis A. Holt
Publikováno v:
Analytical Biochemistry. 275:62-73
pp60 c-src is a prototypical nonreceptor tyrosine kinase and may play a role in diseases as diverse as cancer and osteoporosis. In Src, the SH3 domain (Src homology 3) binds proteins at specific, proline-rich sequences, while the SH2 domain (Src homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb4072a9cc1eea80983e9a4861f87b9
https://doi.org/10.1006/abio.1999.4305
https://doi.org/10.1006/abio.1999.4305
Autor:
Edith A Neidhardt, Jorge E. Godoy, Marie Rose van Schravendijk, Trudy H Grossman, Marcia S. Osburne
Publikováno v:
Journal of Immunological Methods. 224:19-24
The two-domain form of recombinant soluble human CD4 (rsCD4(183)) has been used for structural studies and to probe the interaction of CD4 with its ligands. rsCD4(183) has generally been produced in Escherichia coli in the form of inclusion bodies. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a803a403fb4df3406c875cee4b0b1d
https://doi.org/10.1016/s0022-1759(99)00002-2
https://doi.org/10.1016/s0022-1759(99)00002-2
Autor:
Azis Kongsjahju, Marie-Rose van Schravendijk, Ariamala Gopalsamy, Kristin A. Gordon, Kevin Daniels, Raymond J. Patch, Huai Gao, Paul J. Kowalczyk, Peter V. Pallai, Zhan Shi, John C. Roberts
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2983-2988
A series of lipophilic bis-arylsulfonates was synthesized and evaluated as potential inhibitors of the CD4-gp120 interaction. Structure-activity studies suggested a direct relationship between the nature and extent of lipophilicity and inhibitory pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf3169fcc89251c399d7ebc10f53a51
https://doi.org/10.1016/s0960-894x(96)00552-5
https://doi.org/10.1016/s0960-894x(96)00552-5
Autor:
Yihan Wang, Chester A. Metcalf, Manfred Weigele, Tomi K. Sawyer, David C. Dalgarno, Ian A. MacNeil, Lawrence J. Andrade, William C. Shakespeare, Marie Rose van Schravendijk, Lei Jin, Mary K. Ram, Surinder S. Narula, Raji Sundaramoorthi, Thilo Stehle, Susan Adams, Pierre Schelling, Trudy H Grossman, Jeff Keats, Regine S. Bohacek, T. Keenan
Publikováno v:
Chemical biologydrug design. 67(1)
The tyrosine kinase pp60src (Src) is the prototypical member of a family of proteins that participate in a broad array of cellular signal transduction processes, including cell growth, differentiation, survival, adhesion, and migration. Abnormal Src
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c44832558bf10fb223c2e4bb30368e
https://pubmed.ncbi.nlm.nih.gov/16492148
https://pubmed.ncbi.nlm.nih.gov/16492148
Autor:
Chester A. Metcalf, Ukti Mani, Shiela M. Violette, Tomi K. Sawyer, Susan Adams, Yihan Wang, Terence P. Keenan, Regine S. Bohacek, Marie Rose van Schravendijk, Mary K. Ram, David C. Dalgarno, Selvi Pradeepan, Raji Sundaramoorthi, William C. Shakespeare, Jeffrey A. Keats, Surinder S. Narula, Chad Haraldson, Manfred Weigele, Shuenn Liou
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(18)
Novel bone-targeted 2,6,9-trisubstituted purine template-based inhibitors of Src tyrosine kinase are described. Drug design studies of known purine compounds revealed that both positions-2 and -6 were suitable for incorporating bone-seeking moieties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75987963f2540aebe25650862e108230
https://pubmed.ncbi.nlm.nih.gov/12941335
https://pubmed.ncbi.nlm.nih.gov/12941335
Autor:
Manfred Weigele, Charles J. Eyermann, Berkley A. Lynch, Virginia A. Jacobsen, George P. Luke, Catherine Bartlett, Craig S. Takeuchi, Sue Adams, Karin Stebbins, Ping Li, Shelia Violette, Vaibhav Varkhedkar, Daniel Johnson, Tomi K. Sawyer, William C. Shakespeare, Karina J. Macek, Chad Haraldson, Chester MetcalfIII, Regine S. Bohacek, Michael Yang, Wei Guan, Surinder S. Narula, Frank Cerasoli, Marie Rose van Schravendijk, Ruth W. Yuan, Raji Sundaramoorthi, Marcos Hatada, David C. Dalgarno, Xiaode Lu, Noriyuki Kawahata, Jeremy Smith, Yihan Wang, Susan A. Wood, Ian A. MacNeil
Publikováno v:
Peptides for the New Millennium ISBN: 9780792364450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030d159824387abbc0a14b275f0be716
https://doi.org/10.1007/0-306-46881-6_220
https://doi.org/10.1007/0-306-46881-6_220