Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marie-Rose Abdo"'
Autor:
Jean-Yves Winum, Jérémie Mortier, Pascale Joseph, Marie-Rose Abdo, Stephan Köhler, François Turtaut, Bernard Masereel, Jean-Louis Montero
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2011, 9 (10), pp.3681. ⟨10.1039/c1ob05149k⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2011, 9 (10), pp.3681. ⟨10.1039/c1ob05149k⟩
International audience; In the facultative intracellular pathogen Brucella suis, histidinol dehydrogenase (HDH) activity, catalyzing the last step in histidine biosynthesis, is essential for intramacrophagic replication. The inhibition of this virule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02df7243df499b837c82666478b606c
https://doi.org/10.1039/c1ob05149k
https://doi.org/10.1039/c1ob05149k
Autor:
Jean-Yves Winum, Jean-Louis Montero, Stephan Köhler, Pascale Joseph, Marie-Rose Abdo, Rose-Anne Boigegrain
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2007, 51 (10), pp.3752-5. ⟨10.1128/AAC.00572-07⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2007, 51 (10), pp.3752-5. ⟨10.1128/AAC.00572-07⟩
Brucella suis histidinol dehydrogenase (HDH) can be efficiently targeted by substrate analogues. The growth of this pathogen in minimal medium was inhibited and the multiplication in human macrophages was totally abolished in the presence of the drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003d3e16058205b6d2de840d0c6a2ec6
https://doi.org/10.1128/aac.00572-07
https://doi.org/10.1128/aac.00572-07
Autor:
Mohamed-Chiheb Saada, Marie-Rose Abdo, Daniela Vullo, Jean-Louis Montero, Jean-Yves Winum, Claudiu T. Supuran, Andrea Scozzafava
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19, pp.2440-2443. ⟨10.1016/j.bmcl.2009.03.050⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19, pp.2440-2443. ⟨10.1016/j.bmcl.2009.03.050⟩
Activation of the human carbonic anhydrase (CA, EC 4.2.1.1) isozymes I, II (cytosolic) and IX (transmembrane, tumor-associated isoform) with a series of arylsulfonylhydrazido- l -histidines incorporating 4-substituted-phenyl, pentafluorophenyl- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d427321994de70758a287ddb43b229b
https://pubmed.ncbi.nlm.nih.gov/19345095
https://pubmed.ncbi.nlm.nih.gov/19345095
Autor:
Jean-Yves Winum, Pascale Joseph, Marie-Rose Abdo, Stephan Köhler, Rose-Anne Boigegrain, Jean-Louis Montero
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2008, 23 (3), pp.357-361. ⟨10.1080/14756360701617107⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2008, 23 (3), pp.357-361. ⟨10.1080/14756360701617107⟩
International audience; Histidinol dehydrogenase (HDH, EC EC1.1.1.23) catalyses the final step in the biosynthesis of histidine and constitutes an attractive novel target for the development of new agents against the pathogenous, bacteria Brucella su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3acac8d8941494b7857c262c6aa979
https://pubmed.ncbi.nlm.nih.gov/18569340
https://pubmed.ncbi.nlm.nih.gov/18569340
Autor:
Stephan Köhler, Rose-Anne Boigegrain, Pascale Joseph, Marie-Rose Abdo, Jean-Yves Winum, Jean-Louis Montero, Jean-Pierre Liautard
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2007, 15, pp.4427-4433. ⟨10.1016/j.bmc.2007.04.027⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2007, 15, pp.4427-4433. ⟨10.1016/j.bmc.2007.04.027⟩
Brucella spp. is the causative agent of brucellosis (Malta fever), which is the most widespread zoonosis worldwide. The pathogen is capable of establishing persistent infections in humans which are extremely difficult to eradicate even with antibioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c716f3591624fc2e32f834cd474be953
https://hal.archives-ouvertes.fr/hal-00273226
https://hal.archives-ouvertes.fr/hal-00273226
