Výsledky vyhledávání - "Marie-Pierre Morel"

Akademický článek

Specific inhibition of the JNK pathway promotes locomotor recovery and neuroprotection after mouse spinal cord injury

Autor: Mariaelena Repici, Xiaoru Chen, Marie-Pierre Morel, Mohamed Doulazmi, Alessandra Sclip, Vidjeacoumary Cannaya, Pietro Veglianese, Rudolf Kraftsik, Jean Mariani, Tiziana Borsello, Isabelle Dusart

Publikováno v: Neurobiology of Disease, Vol 46, Iss 3, Pp 710-721 (2012)

Limiting the development of secondary damage represents one of the major goals of neuroprotective therapies after spinal cord injury. Here, we demonstrate that specific JNK inhibition via a single intraperitoneal injection of the cell permeable pepti

Externí odkaz: https://doaj.org/article/96ff9424bcf04b198c9855badc70d2ae

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Akademický článek

Improving axial resolution in confocal microscopy with new high refractive index mounting media.

Autor: Coralie Fouquet, Jean-François Gilles, Nicolas Heck, Marc Dos Santos, Richard Schwartzmann, Vidjeacoumary Cannaya, Marie-Pierre Morel, Robert Stephen Davidson, Alain Trembleau, Susanne Bolte

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121096 (2015)

Resolution, high signal intensity and elevated signal to noise ratio (SNR) are key issues for biologists who aim at studying the localisation of biological structures at the cellular and subcellular levels using confocal microscopy. The resolution re

Externí odkaz: https://doaj.org/article/2618611aa2e54b62adf4dc10d94d7f78

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Hyposialylation Must Be Considered to Develop Future Therapies in Autoimmune Diseases

Autor: Christophe Jamin, Anne Harduin-Lepers, Marie Pierre Morel, Cristina Bagacean, Anne Bordron, Maryvonne Dueymes, Jacques-Olivier Pers, Pierre Pochard

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.3402. ⟨10.3390/ijms22073402⟩
International Journal of Molecular Sciences, 2021, 22 (7), pp.3402. ⟨10.3390/ijms22073402⟩
International Journal of Molecular Sciences, Vol 22, Iss 3402, p 3402 (2021)

International audience; Autoimmune disease development depends on multiple factors, including genetic and environmental. Abnormalities such as sialylation levels and/or quality have been recently highlighted. The adjunction of sialic acid at the term

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5611e4ed43dbc2c4eeb8c8c8030000df
http://hdl.handle.net/20.500.12210/39662

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Loss of floor plate Netrin-1 impairs midline crossing of corticospinal axons and leads to mirror movements

Autor: Quentin Welniarz, Fabio Marti, Marie-Pierre Morel, Nadège Sarrazin, Cecile Gallea, Oriane Pourchet, Emmanuel Roze, Nicolas Heck, Marie Vidailhet, Isabelle Dusart, Alain Chédotal, Sergi Roig Puiggros, Alain Trembleau, Philippe Faure, Juan Antonio Moreno-Bravo, Mohamed Doulazmi

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2021, 34 (3), pp.108654. ⟨10.1016/j.celrep.2020.108654⟩
Cell Reports, 2021, 34 (3), pp.108654. ⟨10.1016/j.celrep.2020.108654⟩

In humans, execution of unimanual movements requires lateralized activation of the primary motor cortex, which then transmits the motor command to the contralateral hand through the crossed corticospinal tract (CST). Mutations in NTN1 alter motor con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538deab0aa18c1d2510ce3028ce9cd94

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Non cell-autonomous role of DCC in the guidance of the corticospinal tract at the midline

Autor: Marie-Pierre Morel, Emmanuel Roze, Aurélie Méneret, Vanessa Brochard, Alain Trembleau, Oriane Pourchet, Oriane Trouillard, Mohamed Doulazmi, Marta Ruiz, Quentin Welniarz, Sabine Meunier, Alain Chédotal, Isabelle Dusart, Jean-Charles Lamy, Morgane Belle, Marie Vidailhet, Cecile Gallea, Massimo Cincotta

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.410. ⟨10.1038/s41598-017-00514-z⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, 2017, 7 (1), pp.410. ⟨10.1038/s41598-017-00514-z⟩

DCC, a NETRIN-1 receptor, is considered as a cell-autonomous regulator for midline guidance of many commissural populations in the central nervous system. The corticospinal tract (CST), the principal motor pathway for voluntary movements, crosses the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b711fc566a669148a13ebe031890f9
https://hal.sorbonne-universite.fr/hal-01502372/document

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Mutations in the netrin-1 gene cause congenital mirror movements

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2017, ⟨10.1172/JCI95442⟩
Journal of Clinical Investigation, 2017, ⟨10.1172/JCI95442⟩

Netrin-1 is a secreted protein that was first identified 20 years ago as an axon guidance molecule that regulates midline crossing in the CNS. It plays critical roles in various tissues throughout development and is implicated in tumorigenesis and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44c6ebfc95a1050f7d2f0f2c10a57ee
https://hal.archives-ouvertes.fr/hal-02390035

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Mature Purkinje Cells Require the Retinoic Acid-Related Orphan Receptor-α (RORα) to Maintain Climbing Fiber Mono-Innervation and Other Adult Characteristics

Autor: Xiao Ru Chen, Vidjeacoumary Cannaya, Rachel M. Sherrard, Laure Rondi-Reig, Rosine Wehrlé, Ann M. Lohof, Hasan X. Avci, Mohamed Doulazmi, Isabelle Dusart, Jean Mariani, Constantino Sotelo, Guilan Vodjdani, Nicolas Heck, Christelle Rochefort, Marie-Pierre Morel, Serge Marty

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, 2013, 33 (22), pp.9546+. ⟨10.1523/JNEUROSCI.2977-12.2013⟩
Journal of Neuroscience, Society for Neuroscience, 2013, 33 (22), pp.9546+. ⟨10.1523/JNEUROSCI.2977-12.2013⟩

Neuronal maturation during development is a multistep process regulated by transcription factors. The transcription factor RORα (retinoic acid-related orphan receptor α) is necessary for early Purkinje cell (PC) maturation but is also expressed thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b35f833b62592e5a83aadc3d3bac110
https://doi.org/10.1523/jneurosci.2977-12.2013

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Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord

Autor: Marie-Pierre Morel, Emeline Camand, Isabelle Dusart, Constantino Sotelo, Andreas Faissner

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, 2004, 20, pp.1161-1176. ⟨10.1111/j.1460-9568.2004.03558.x⟩
European Journal of Neuroscience, Wiley, 2004, 20, pp.1161-1176. ⟨10.1111/j.1460-9568.2004.03558.x⟩

The scarring process occurring after adult central nervous system injury and the subsequent increase in the expression of certain extracellular matrix molecules are known to contribute to the failure of axon regeneration. This study provides an immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fc9a8a9add6edf4f00e088b1b8b7eb
https://doi.org/10.1111/j.1460-9568.2004.03558.x

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Autor: Isabelle Dusart, Constantino Sotelo, Marie Pierre Morel

Publikováno v: Journal of Neurocytology. 31:633-647

Adult rat Purkinje cells are extremely resistant to axotomy and, although they lack spontaneous regeneration, are able to sprout. Axon sprouting is a late process that occurs mainly 6 to 18 months after the lesion and results from an interplay betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::954d59c584eadd28d41ab91d326ac85d
https://doi.org/10.1023/a:1025739511646

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