Výsledky vyhledávání - "Marie-Pierre Gaub"

Akademický článek

MiRNA genes constitute new targets for microsatellite instability in colorectal cancer.

Autor: Nizar El-Murr, Zoulira Abidi, Kristell Wanherdrick, Magali Svrcek, Marie-Pierre Gaub, Jean-François Fléjou, Richard Hamelin, Alex Duval, Thécla Lesuffleur

Publikováno v: PLoS ONE, Vol 7, Iss 2, p e31862 (2012)

Mismatch repair-deficient colorectal cancers (CRC) display widespread instability at DNA microsatellite sequences (MSI). Although MSI has been reported to commonly occur at coding repeats, leading to alterations in the function of a number of genes e

Externí odkaz: https://doaj.org/article/944ac0c819714ef8a1a9c5958ed67ffd

Zobrazit plný text záznamu

Supplementary Data from Marked Activity of Irinotecan and Rapamycin Combination toward Colon Cancer Cells In vivo and In vitro Is Mediated through Cooperative Modulation of the Mammalian Target of Rapamycin/Hypoxia-Inducible Factor-1α Axis

Autor: Dominique Guenot, Marie-Pierre Gaub, Annette K. Larsen, Pierre Oudet, Anne-Claire Voegeli, Isabelle Lelong-Rebel, Céline Nicolet, Eric Guérin, Erwan Pencreach

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af5ddc1473737c4e9e5e98c11a2eb95
https://doi.org/10.1158/1078-0432.22439977.v1

Zobrazit plný text záznamu

Data from Marked Activity of Irinotecan and Rapamycin Combination toward Colon Cancer Cells In vivo and In vitro Is Mediated through Cooperative Modulation of the Mammalian Target of Rapamycin/Hypoxia-Inducible Factor-1α Axis

Autor: Dominique Guenot, Marie-Pierre Gaub, Annette K. Larsen, Pierre Oudet, Anne-Claire Voegeli, Isabelle Lelong-Rebel, Céline Nicolet, Eric Guérin, Erwan Pencreach

Purpose: Despite recent progress, colon cancer is often resistant to combination chemotherapy, highlighting the need for development of novel therapeutic approaches. An attractive target is hypoxia-inducible factor-1α (HIF-1α), a key transcription

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c0c9de2431a12e4233e37beac9721e
https://doi.org/10.1158/1078-0432.c.6517357.v1

Zobrazit plný text záznamu

Carcinomes bronchiques non à petites cellules (CBNPC) métastatiques, mutés ou réarrangés : comment déterminer la cible ?

Autor: Eric Guérin, Erwan Pencreach, Véronique Lindner, Marie Pierre Gaub, Noëlle Weingertner, Michèle Legrain, P. Le Van Quyen, Marie-Pierre Chenard, Anne-Claire Voegeli, Anne Schneider, S. Renaud, C. Emprou, Michèle Beau-Faller

Publikováno v: Revue des Maladies Respiratoires Actualités. 7:476-496

Resume Les progres dans le demantelement moleculaire des CBNPC ont conduit a des avancees significatives dans le traitement des tumeurs solides. Les alterations moleculaires qui peuvent etre ciblables par des therapeutiques ciblees correspondent soit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8bd171d2646a1dfd06bed4ab98dc498
https://doi.org/10.1016/s1877-1203(16)30031-3

Zobrazit plný text záznamu

PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer

Autor: Janick Selves, Valérie Jooste, Laurent Martin, Dominique Guenot, Alex Duval, Côme Lepage, Sylviane Olschwang, Michè le Legrain, Laetitia Marisa, Anne-Marie Bouvier, Delphine Lecorre, Sylvain Kirzin, Marie-Christine Etienne-Grimaldi, Gérard Milano, Gilles Manceau, Marie-Pierre Gaub, Valérie Boige, Pierre Laurent-Puig

Publikováno v: Cancer Medicine
Cancer Medicine, Wiley, 2015, 4 (3), pp.371-382. ⟨10.1002/cam4.370⟩
Cancer medicine
Cancer medicine, 2015, 4 (3), pp.371-382. ⟨10.1002/cam4.370⟩
Cancer Medicine, 2015, 4 (3), pp.371-382. ⟨10.1002/cam4.370⟩
Cancer medicine, 2015, 4 (3), pp.371-382. 〈10.1002/cam4.370〉

International audience; PIK3CA, which encodes the p110α catalytic subunit of PI3Kα, is one of the most frequently altered oncogenes in colon cancer (CC), but its prognostic value is still a matter of debate. Few reports have addressed the associati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306976a8466bab159e3b5a5756a14181
https://doi.org/10.1002/cam4.370

Zobrazit plný text záznamu

Plný text ve formátu HTML

Intérêt du génotypage de l’UGT1A1 dans le cadre du traitement des cancers digestifs par irinotécan

Autor: Fabienne Thomas, Jean-Christophe Boyer, Laurent Philibert, Nicolas Picard, Marie-Pierre Gaub, Marie-Christine Etienne-Grimaldi, Marie-Claude Gagnieu, Sylvie Quaranta, Franck Broly, Cécile Ged, François Ghiringhelli, Valérie Le Morvan, Delphine Poncet, Chantal Le Guellec, Marie-Anne Loriot, Régis Bouquié

Publikováno v: Bulletin du Cancer. 101:533-553

Resume L’irinotecan est un agent cytotoxique largement utilise dans le traitement des cancers colorectaux avances. Son activite anticancereuse depend de sa bioactivation en metabolite SN38 et son elimination se fait sous forme glucuronoconjuguee pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::042b3a0d89ba362e2dded4a396b4498b
https://doi.org/10.1684/bdc.2014.1933

Zobrazit plný text záznamu

Role of Topoisomerases in Pediatric High Grade Osteosarcomas: TOP2A Gene Is One of the Unique Molecular Biomarkers of Chemoresponse

Autor: Marie-Pierre Gaub, Erwan Pencreach, Eric Guérin, Dominique Guenot, Luc Marcellin, Natacha Entz-Werle, Christelle Lasthaus, Aurelia Nguyen

Publikováno v: Cancers, Vol 5, Iss 2, Pp 662-675 (2013)
Cancers
Cancers; Volume 5; Issue 2; Pages: 662-675

Currently, the treatment of pediatric high-grade osteosarcomas systematically includes one topoisomerase IIα inhibitor. This chemotherapy is usually adapted to the response to the neo-adjuvant therapy after surgery. The current and unique marker of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d1da363a6a4bbc47d84e420d5568ef
http://www.mdpi.com/2072-6694/5/2/662

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání