Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marie-Pier Cloutier"'
Autor:
Jugurtha Ouboudinar, Ramon Corpuz, Martin Leduc, Jean-Simon Duceppe, Alexandre Laverdure, Mikaël Tremblay, Kathy Hince, Amélie Blais, Marie-Pier Cloutier, Richard L. Hébert, Christopher R.J. Kennedy, Alexandra Blais, Liette Gervais, Lilianne Geerts, Lyne Gagnon, Pierre Laurin, Jean-Christophe Simard, Steven R. LaPlante, Sylvie Létourneau, Jean-Francois Thibodeau, François A. Leblond, Brigitte Grouix, Shaun D. Abbott, Boulos Zacharie, Alexandra Felton, Vanessa Marques Quintela, William Gagnon, François Sarra-Bournet
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Non-alcoholic Fatty Liver Disease (NAFLD) is the most common form of liver disease and is associated with metabolic dysregulation. Although G protein-coupled receptor 84 (GPR84) has been associated with inflammation, its role in metabolic regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7b27b3602799ec5543996bcf182aca
http://europepmc.org/articles/PMC7391726
http://europepmc.org/articles/PMC7391726
Autor:
Jean-Francois Thibodeau, Alexandre Laverdure, Kathy Hince, Richard L. Hébert, Alex Gutsol, William Gagnon, Martin Leduc, Eldjonai Kamto, Liette Gervais, Shaun D. Abbott, Christopher R.J. Kennedy, Francois A. Leblond, Jonathan Richard, Pierre Laurin, Chet E. Holterman, Alexandra Felton, Ming-Zhi Zhang, François Sarra-Bournet, Mikaël Tremblay, Jugurtha Ouboudinar, Lilianne Geerts, Christopher Penney, Lyne Gagnon, Jocelyn Dupuis, Jean-Christophe Simard, Jean-Simon Duceppe, Quang Trinh Nguyen, Marie-Pier Cloutier, Raymond C. Harris, Angelino Calderone, Brigitte Grouix, Boulos Zacharie, Sylvie Létourneau
Publikováno v:
The American Journal of Pathology. 188:1132-1148
Numerous clinical conditions can lead to organ fibrosis and functional failure. There is a great need for therapies that could effectively target pathophysiological pathways involved in fibrosis. GPR40 and GPR84 are G protein–coupled receptors with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7315d43b6a70e40dd65fdef9ae6ea14c
https://doi.org/10.1016/j.ajpath.2018.01.009
https://doi.org/10.1016/j.ajpath.2018.01.009
Autor:
Jonathan Richard, Lyne Gagnon, Jean-Christophe Simard, Brigitte Grouix, Liette Gervais, Pierre Laurin, Alexandre Laverdure, Marie-Pier Cloutier, Alexandra Felton
Publikováno v:
Nephrology Dialysis Transplantation. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ee5d55d953c76f21bcf70ba45b12a63
https://doi.org/10.1093/ndt/gfz103.sp436
https://doi.org/10.1093/ndt/gfz103.sp436
Autor:
Chris R. J. Kennedy, Marie-Pier Cloutier, François A. Leblond, Pierre Laurin, Jean-Francois Thibodeau, Chet E. Holterman, Lyne Gagnon, Jean-Christophe Simard, Richard L. Hébert
Publikováno v:
Nephrology Dialysis Transplantation. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caacd071f4a273a024a8ccc89b9ae5b3
https://doi.org/10.1093/ndt/gfz106.fp266
https://doi.org/10.1093/ndt/gfz106.fp266
Autor:
Chet E. Holterman, Marie-Pier Cloutier, Lyne Gagnon, Jean-Christophe Simard, Amélie Blais, Richard L. Hébert, Jean-Francois Thibodeau, Francois A. Leblond, Brigitte Grouix, Thalia Medeiros, Martin Leduc, Dylan Burger, Christopher R.J. Kennedy
Publikováno v:
Clinical science (London, England : 1979). 133(14)
PBI-4050 (3-pentylbenzenacetic acid sodium salt), a novel first-in-class orally active compound that has completed clinical Phases Ib and II in subjects with chronic kidney disease (CKD) and metabolic syndrome respectively, exerts antifibrotic effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5775ed87b11ca874d6cdb837464939fb
https://pubmed.ncbi.nlm.nih.gov/31308217
https://pubmed.ncbi.nlm.nih.gov/31308217
Autor:
Marie-Pier Cloutier, François A. Leblond, Brigitte Grouix, Alexandre Laverdure, Mikaël Tremblay, Jonathan Richard, Liette Gervais, François Sarra-Bournet, Pierre Laurin, Alexandra Felton, Lyne Gagnon
Publikováno v:
Diabetes. 67
Introduction and Aims: Given the expected rise in the prevalence of obesity and type 2 diabetes, hepatic steatosis will, if not already, become an epidemic. The aim of this study was to determine the mechanism of action of PBI-4547 on diabetic compli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::545d834fba401e1a6f4a0a8990f1f160
https://doi.org/10.2337/db18-2000-p
https://doi.org/10.2337/db18-2000-p
Autor:
Alexandre Laverdure, Jonathan Richard, Marie-Pier Cloutier, Lyne Gagnon, Liette Gervais, Jean-Christophe Simard, Pierre Laurin, François A. Leblond, Brigitte Grouix, Alexandra Felton, Martin Leduc
Publikováno v:
Diabetes. 67
Background: PBI-4050 displays anti-inflammatory/fibrotic properties with metabolic regulation. PBI-4050 has been shown to reduce glycated hemoglobin levels, and different biomarkers related to kidney and heart injury in a phase II open label clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0d0fbb83e88d4c823624545d53d49d
https://doi.org/10.2337/db18-503-p
https://doi.org/10.2337/db18-503-p
Autor:
Mikaël Tremblay, William Gagnon, Martin Leduc, Marie-Pier Cloutier, Lyne Gagnon, François A. Leblond, Brigitte Grouix, François Sarra-Bournet, Jean-Christophe Simard, Pierre Laurin, Kathy Hince, Sylvie Létourneau
Publikováno v:
Diabetes. 67
Introduction: PBI-4547 is a novel orally active compound that is being developed for potential clinical use in patients suffering from metabolic and inflammatory/fibrosis-related diseases. This study examined the effect of PBI-4547 in NOD mice, a mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6346ba959877b8d9652ca33144b17a5e
https://doi.org/10.2337/db18-1817-p
https://doi.org/10.2337/db18-1817-p
Autor:
Alexandre Laverdure, Marie-Pier Cloutier, Jonathan Richard, Alexandra Felton, Mikaël Tremblay, Brigitte Grouix, Liette Gervais, Lyne Gagnon, Pierre Laurin, François Sarra-Bournet
Publikováno v:
Journal of Hepatology. 70:e86-e87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::654c4ee979d37ab2ad4f68ec988b739b
https://doi.org/10.1016/s0618-8278(19)30152-5
https://doi.org/10.1016/s0618-8278(19)30152-5
Autor:
Lilianne Geerts, François Sarra-Bournet, Pierre Laurin, Marie-Pier Cloutier, Brigitte Grouix, Alexandra Felton, Mikaël Tremblay, Lyne Gagnon
Publikováno v:
Diffuse Parenchymal Lung Disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f731a1bf1ba0df406319ad9a031718
https://doi.org/10.1183/1393003.congress-2017.pa910
https://doi.org/10.1183/1393003.congress-2017.pa910