Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marie-Paule Bouche"'
Autor:
Lieven Baert, Marie-Paule Bouche, Eva Hoeben, Gerben Albert Eleutherius Van 'T Klooster, Frans van Velsen, Adriana Looszova, Herman Borghys
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:2042-2050
The next-generation human immunodeficiency virus type 1 (HIV-1) nonnucleoside reverse transcriptase inhibitor rilpivirine (TMC278) was administered in rats and dogs as single intramuscular (IM) or subcutaneous (SC) injections, formulated as a 200-nm
Autor:
Anne Van Hecken, Guy Van den Mooter, Marie-Paule Bouche, Jan de Hoon, Paul Prinsen, Geert Verreck, Tinne Daems, K. Six, Marleen Depré, Jef Peeters, Marcus E. Brewster
Publikováno v:
European Journal of Pharmaceutical Sciences. 24:179-186
The aim of this study was to investigate the performance of three new solid dispersion formulations of itraconazole in human volunteers in comparison with Sporanox, the marketed form. Solid dispersions made up of itraconazole (40%, w/w) and HPMC 2910
Autor:
J. Van Bocxlaer, Eric Mortier, Michel Struys, Marie-Paule Bouche, Georges Rolly, Linda Versichelen, D. Dyzers, Wim Goeteyn, Y. D. I. Vandevivere
Publikováno v:
Anaesthesia. 59:584-589
Summary Two new generation carbon dioxide absorbents, DragerSorbFree and AmsorbPlus, were studied in vitro for formation of compound A or carbon monoxide, during minimal gas flow (500 ml.min )1 ) with sevoflurane or desflurane. Compound A was assesse
Publikováno v:
Journal of Analytical Toxicology. 26:35-42
This report describes a fully elaborated and validated method for quantitation of the hydrocarbons n-propane, iso-butane, and n-butane in blood samples. The newly developed analytical procedure is suitable for both emergency cases and forensic medici
Autor:
Georges Rolly, Eric Mortier, Michel Struys, Marie-Paule Bouche, Linda Versichelen, Jan Van Bocxlaer, André P. De Leenheer
Publikováno v:
Anesthesiology. 95:750-755
Background Insufficient data exist on the production of compound A during closed-system sevoflurane administration with newer carbon dioxide absorbents. Methods A modified PhysioFlex apparatus (Dräger, Lübeck, Germany) was connected to an artificia
Autor:
Michel Struys, Linda Versichelen, Georges Rolly, Eric Mortier, André P. De Leenheer, Marie-Paule Bouche, Jan Van Bocxlaer
Publikováno v:
Clinical Chemistry. 47:281-291
Background: During low-flow or closed-circuit anesthesia with the fluorinated inhalation anesthetic sevoflurane, compound A, an olefinic degradation product with known nephrotoxicity in rats, is generated on contact with alkaline CO2 adsorbents. To e
Autor:
Eric Mortier, Jan Van Bocxlaer, Marie-Paule Bouche, Linda Versichelen, Catherine Van der herten, Michel Struys, Georges Rolly, André P. De Leenheer
Publikováno v:
Anesthesiology. 93:1064-1068
Background Few data exist on compound A during sevoflurane anesthesia when using closed-circuit conditions and sodalime with modern computer-controlled liquid injection. Methods A PhysioFlex apparatus (Dräger, Lübeck, Germany) was connected to an a
Autor:
Marie-Paule Bouche, Brian Woodfall, Goedele De Smedt, Monika Peeters, Richard M. W. Hoetelmans, Hilde Vanaken, Monika Schöller-Gyüre, Thomas N. Kakuda
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Drug–drug interactions with acid-suppressing agents were previously described with several other antiretroviral drugs. • Etravirine (TMC125) is a next-generation non-nucleoside reverse transcriptase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398ad9a2a5fe3dbfdc6be6a12b03dfce
https://europepmc.org/articles/PMC2561103/
https://europepmc.org/articles/PMC2561103/
Autor:
Murali Pendela, Pieter Van Remoortere, Wigerinck Piet Tom Bert Paul, Hilde De Man, Laurent Schueller, Marie-Paule Bouche, Elke Van Gyseghem, Jan Rosier, Guy Van den Mooter, Gerben Albert Eleutherius Van 'T Klooster, Lieven Baert, Jos Hoogmartens, Erwin Adams
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 70(3)
Powders for reconstitution of the next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC278 with low water solubility were developed by using a spray-dry technology. Their flexible dosing ability makes them suitable for patients l
Autor:
L. Lammens, Werner Coussement, Marie-Paule Bouche, Sandra De Jonghe, Sophie Lachau-Durand, B. Willems, Johan Verbeeck, Sofie Starckx, Petra Vinken
Publikováno v:
Toxicologic pathology. 36(2)
Dietary dosing of the non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC125, under development for treatment of HIV-1, resulted in a syndrome in male mice in a previous experiment that was termed hemorrhagic cardiomyopathy. In literature, thi