Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie-Odile Vallez"'
Autor:
Isabelle Lapret, Philippe Delerive, Florence Petit-Dop, Paul Declerck, Isabelle Tupinon-Mathieu, Patricia Sansilvestri-Morel, Philippe Baumy, Marie-Odile Vallez, Alain Rupin, Florence Bertin, Schaffner Arnaud-Pierre, Philippe Mennecier
Publikováno v:
Thrombosis Research. 204:81-87
Enhancement of fibrinolysis constitutes a promising approach to treat thrombotic diseases. Venous thrombosis and thromboembolism risks are associated with increased plasma levels of TAFI (Thrombin Activatable Fibrinolysis Inhibitor) as well as its ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0a135e41c23899c73c0638a89a778b
https://doi.org/10.1016/j.thromres.2021.06.007
https://doi.org/10.1016/j.thromres.2021.06.007
Autor:
Marie-Odile Vallez, Elisabeth Ruano, Philippe Mennecier, Nicole Despaux, Thierry Persigand, Patrice Desos, Philippe Gloanec, Alain Rupin, Eric Raimbaud, Patricia Sansilvestri-Morel, Schaffner Arnaud-Pierre
Publikováno v:
Journal of medicinal chemistry. 64(7)
Selective and potent inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa) have the potential to increase endogenous and therapeutic fibrinolysis and to behave like profibrinolytic agents without the risk of major hemorrhage, si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99eaf3f8fe1829b8b377beebac433d88
https://pubmed.ncbi.nlm.nih.gov/33764059
https://pubmed.ncbi.nlm.nih.gov/33764059
Autor:
Marie-Odile Vallez, P. Mennecier, I. Marx, Philippe Gloanec, T. J. Verbeuren, A. Rupin, G. De Nanteuil
Publikováno v:
Journal of Thrombosis and Haemostasis. 9:1375-1382
Summary. Objectives: Dabigatran etexilate is the first oral thrombin inhibitor to demonstrate superior efficacy to warfarin for stroke prevention in patients with atrial fibrillation. This study describes the in vitro, ex vivo anticoagulant and in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe377efccd8390b849d9a9aa717c253
https://doi.org/10.1111/j.1538-7836.2011.04286.x
https://doi.org/10.1111/j.1538-7836.2011.04286.x
Publikováno v:
Thrombosis and Haemostasis. 86:1528-1531
SummaryTo investigate the role of active plasminogen activator inhibitor 1 (PAI-1) in the evolution of a microthrombus generated in the arteriolar microcirculation, the monoclonal antibody, 33H1F7, which transforms active PAI-1 to a tissue type plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af257bcd66f9805299b9ad99a23520ec
https://doi.org/10.1055/s-0037-1616758
https://doi.org/10.1055/s-0037-1616758
Publikováno v:
British Journal of Pharmacology. 122:859-866
1 The present study was designed to investigate a possible role of thromboxane A2 (TXA2) on arteriolar vasomotion (spontaneous rhythmic variations of the vessel diameter). Therefore the microcirculatory effects of the thromboxane-receptor (TP-recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64b4eab4a4fd5c2b9f0827620237bd84
https://doi.org/10.1038/sj.bjp.0701464
https://doi.org/10.1038/sj.bjp.0701464
Autor:
Isabelle Marx, Olivier D. Christophe, Alain Rupin, Cécile V. Denis, Tony Verbeuren, Peter J. Lenting, Marie-Odile Vallez
Publikováno v:
Blood. 112(3)
The role of von Willebrand factor (VWF) in thrombosis involves its binding to a number of ligands. To investigate the relative importance of these particular interactions in the thrombosis process, we have introduced mutations into murine VWF (mVWF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7ad1fb3be7793c3539cafe3411b236
https://pubmed.ncbi.nlm.nih.gov/18487513
https://pubmed.ncbi.nlm.nih.gov/18487513
Autor:
Christine Lila-Ambroise, Marie-Odile Vallez, Guillaume De Nanteuil, Alain Rupin, Tony Verbeuren
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(10)
The synthesis and activity of novel benzothiophene derivatives are described. In the t-Pa-induced fibrin clot lysis assay, several compounds inhibit the formation of the tPa–PAI-1 complex with submicromolar IC 50 . This class of compounds potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204dd54c780d1f95a55faae75b05c25f
https://pubmed.ncbi.nlm.nih.gov/12729646
https://pubmed.ncbi.nlm.nih.gov/12729646
Autor:
Thierry Dubuffet, Marie-Odile Vallez, Gilbert Lavielle, Tony Verbeuren, Jean-Jacques Descombes, Serge Simonet
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489918123
Thromboxane (TXA2) causes platelet aggregation, vasoconstriction and cell proliferation through the activation of specific cell membrane TP-receptors1, 2. TXA2 is implicated in thrombotic disorders and TP-receptor antagonists have been described as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92326247ecfd6945382af337c796aa9b
https://doi.org/10.1007/978-1-4899-1810-9_35
https://doi.org/10.1007/978-1-4899-1810-9_35
Publikováno v:
Journal of Thrombosis and Haemostasis. 1:P2042-P2042
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b89a1602eed9a1c208f36b3dd822f0f9
https://doi.org/10.1111/j.1538-7836.2003.tb05526.x
https://doi.org/10.1111/j.1538-7836.2003.tb05526.x