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pro vyhledávání: '"Marie-Luise Lubos"'
Autor:
Marie-Luise Lubos, Stefanie Norkowski, Anne-Sophie Stolle, Britta Körner, Christian Rüter, M. Alexander Schmidt, Philip R. Hardwidge, Lilo Greune
Publikováno v:
Cellular and Molecular Life Sciences. 75:2273-2289
Effector proteins are key virulence factors of pathogenic bacteria that target and subvert the functions of essential host defense mechanisms. Typically, these proteins are delivered into infected host cells via the type III secretion system (T3SS).
Publikováno v:
International journal of medical microbiology : IJMM. 308(7)
Microbial pathogens have developed intriguing molecular strategies to modulate and/or control host cell functions to ensure their own survival and replication. During this molecular interplay between microbes and their respective hosts especially sec
Autor:
Jürgen Heesemann, Julia Scharnert, Benjamin Grabowski, M. Alexander Schmidt, Antje Flieger, Dominik von Tils, Marija Poceva, James B. Bliska, Christian Rüter, Marie-Luise Lubos, Mariana Ruiz Silva
Publikováno v:
International Journal of Medical Microbiology. 304:444-451
The Yersinia outer protein M (YopM) is a type 3 secretion system (T3SS)-dependent effector protein of Yersinia enterocolitica , Yersinia pseudotuberculosis and Yersinia pestis . Although YopM is indispensable for full virulence, its molecular functio
Autor:
Marie-Luise Lubos, Lilo Greune, Christian Rüter, Dagmar Zeuschner, Julia Scharnert, M. Alexander Schmidt
Publikováno v:
Cellular and Molecular Life Sciences. 70:4809-4823
Extracellular Gram-negative pathogenic bacteria target essential cytoplasmic processes of eukaryotic cells by using effector protein delivery systems such as the type III secretion system (T3SS). These secretion systems directly inject effector prote
Autor:
Leigh Ann Feuerbacher, Xiaogang Wang, Thanh H. Pham, Chad Slawson, Arcady Mushegian, Marie-Luise Lubos, Philip R. Hardwidge, Rachel Olsen, Minzhao Huang, Xiaofei Gao
Publikováno v:
Cell Host & Microbe. 13(1):87-99
Summary Modulation of NF-κB-dependent responses is critical to the success of attaching/effacing (A/E) human pathogenic E. coli (EPEC and EHEC) and the natural mouse pathogen Citrobacter rodentium . NleB, a highly conserved type III secretion system
Autor:
Stefanie Norkowski, Anne-Sophie Stolle, Christian Rüter, M. Alexander Schmidt, Marie-Luise Lubos, Ülo Langel
Publikováno v:
Inflammation and Cell Signaling.
Previous studies identified the effector protein YopM of Yersinia enterocolitica as a novel bacterial cell-penetrating protein. YopM’s ability to translocate across the host cell plasma membrane independently of Yersinia’s type III secretion syst