Výsledky vyhledávání - "Marie-Luise Eschbach"

Akademický článek

Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.

Autor: Birte Blankenhaus, Martina Reitz, Yannick Brenz, Marie-Luise Eschbach, Wiebke Hartmann, Irma Haben, Tim Sparwasser, Jochen Huehn, Anja Kühl, Thorsten B Feyerabend, Hans-Reimer Rodewald, Minka Breloer

Publikováno v: PLoS Pathogens, Vol 10, Iss 2, p e1003913 (2014)

Accumulating evidence suggests that IL-9-mediated immunity plays a fundamental role in control of intestinal nematode infection. Here we report a different impact of Foxp3⁺ regulatory T cells (Treg) in nematode-induced evasion of IL-9-mediated immu

Externí odkaz: https://doaj.org/article/4ddcecfed62d41c3b6fb6b10b9d31484

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Strongyloides ratti infection modulates B and T cell responses to third party antigens

Autor: Marie-Luise Eschbach, Minka Breloer, Wiebke Hartmann

Publikováno v: Experimental Parasitology. 132:69-75

It is estimated that over one third of the world population is infected with helminths, Strongyloides ssp. accounting for approximately 30–100 million cases. As helminth infections often result in a modulation of the host’s immune system, infecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b76c32fd0dca2bcc52ac102c38dfb8
https://doi.org/10.1016/j.exppara.2011.06.001

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Efficient control of Plasmodium yoelii infection in BALB/c and C57BL/6 mice with pre-existing Strongyloides ratti infection

Autor: Minka Breloer, Julia Kolbaum, Marie-Luise Eschbach, Thomas Jacobs, Bernhard Fleischer, Christiane Steeg

Publikováno v: Parasite Immunology. 34:388-393

About 225 million malaria cases have been reported worldwide in 2009, and one-third of the world's population is infected with parasitic helminths. As helminths and Plasmodium are co-endemic, concurrent infections frequently occur. Helminths have bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9e5aa01ebe8ff39fba6d7648f5e861c
https://doi.org/10.1111/j.1365-3024.2012.01369.x

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Vaccination with Strongyloides ratti heat shock protein 60 increases susceptibility to challenge infection by induction of Th1 response

Autor: Klaus D. Erttmann, Minka Breloer, Manchang Tanyi Kingsley, Melanie Piédavent, Marie-Luise Eschbach, Anke Osterloh, Norbert W. Brattig, Eva Liebau, Bernhard Fleischer, Nadia Ben Nouir

Publikováno v: Vaccine. 30:862-871

The control of strongyloidiasis affecting approximately 100 million people - caused by the gastrointestinal nematode Strongyloides stercoralis - is still based on anti-helminthic treatment. In the current study we analysed the immune response to Stro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5c1cbc49fafb9de3371f7e9cf109a7
https://doi.org/10.1016/j.vaccine.2011.11.110

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Strongyloides ratti Infection Induces Expansion of Foxp3+ Regulatory T Cells That Interfere with Immune Response and Parasite Clearance in BALB/c Mice

Autor: Marie-Luise Eschbach, Tim Sparwasser, Birte Blankenhaus, Thomas Jacobs, Ulrike Klemm, Minka Breloer, Christoph Loddenkemper, Anja A. Kühl, Jochen Huehn

Publikováno v: The Journal of Immunology. 186:4295-4305

To escape expulsion by their host’s immune system, pathogenic nematodes exploit regulatory pathways that are intrinsic parts of the mammalian immune system, such as regulatory T cells (Tregs). Using depletion of Treg mice, we showed that Foxp3+ Tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0ac5be34c62e6bde7736e67370b299
https://doi.org/10.4049/jimmunol.1001920

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Efficient control of Leishmania and Strongyloides despite partial suppression of nematode-induced Th2 response in co-infected mice

Autor: Julia Kolbaum, Minka Breloer, N. Brewig, N. Zimara, Uwe Ritter, Marie-Luise Eschbach

Publikováno v: Parasite Immunology. 33:226-235

Endemic regions for the pathogenic nematode Strongyloides and parasitic protist Leishmania overlap and therefore co-infections with both parasites frequently occur. As the Th2 and Th1 immune responses necessary to efficiently control Strongyloides an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87533848ba2245091b4fdfe6873afe22
https://doi.org/10.1111/j.1365-3024.2010.01273.x

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Strongyloides rattiinfection induces transient nematode-specific Th2 response and reciprocal suppression of IFN-γ production in mice

Autor: Norbert W. Brattig, Birte Blankenhaus, U. Klemm, Minka Breloer, Marie-Luise Eschbach, J. Kolbaum

Publikováno v: Parasite Immunology. 32:370-383

Summary Over one-third of the world population is infected with parasitic helminths, Strongyloides ssp. accounting for approximately 30–100 million infected people. In this study, we employ the experimental system of murine Strongyloides ratti infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5a6542047d85b656de43522eff2cd2
https://doi.org/10.1111/j.1365-3024.2010.01199.x

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Secretion of an acid phosphatase provides a possible mechanism to acquire host nutrients byPlasmodium falciparum

Autor: Carsten Wrenger, Rolf D. Walter, Bärbel Bergmann, Ingrid B. Müller, Marie-Luise Eschbach, Julia Knöckel

Publikováno v: Cellular Microbiology. 12:677-691

Summary As an intracellular proliferating parasite, Plasmodium falciparum exploits the human host to acquire nutrients. However, nutrients such as nucleotides and cofactors are mostly phosphorylated in the host cell cytosol and thus have to be dephos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d585ee9769d0ff4604046164c12e664
https://doi.org/10.1111/j.1462-5822.2010.01426.x

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Cloning, expression, characterisation and three-dimensional structure determination ofCaenorhabditis elegansspermidine synthase

Autor: Nashya Haider, Tobias Karlberg, Kai Lüersen, Salam Al-Karadaghi, Rolf D. Walter, Marie-Luise Eschbach, Veronica Tamu Dufe

Publikováno v: FEBS Letters. 579:6037-6043

The polyamine synthesis enzyme spermidine synthase (SPDS) has been cloned from the model nematode Caenorhabditis elegans. Biochemical characterisation of the recombinantly expressed protein revealed a high degree of similarity to other eukaryotic SPD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9f5fa4a395d56e77028acd4232840c
https://doi.org/10.1016/j.febslet.2005.09.050

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Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice

Autor: Hans Reimer Rodewald, Minka Breloer, Anja A. Kühl, Yannick Brenz, Birte Blankenhaus, Wiebke Hartmann, Irma Haben, Marie Luise Eschbach, Thorsten B. Feyerabend, Martina Reitz, Tim Sparwasser, Jochen Huehn

Publikováno v: PLoS Pathogens, Vol 10, Iss 2, p e1003913 (2014)
PLoS Pathogens

Accumulating evidence suggests that IL-9-mediated immunity plays a fundamental role in control of intestinal nematode infection. Here we report a different impact of Foxp3+ regulatory T cells (Treg) in nematode-induced evasion of IL-9-mediated immuni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819af692160bee4a7a0897b4d75e6189
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24516385/pdf/?tool=EBI

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