Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marie-Louise Trotman"'
Autor:
Mark G, Lebwohl, Kim A, Papp, Linda, Stein Gold, Melinda J, Gooderham, Leon H, Kircik, Zoe D, Draelos, Steven E, Kempers, Mathew, Zirwas, Kathleen, Smith, David W, Osborne, Marie-Louise, Trotman, Lynn, Navale, Charlotte, Merritt, David R, Berk, Howard, Welgus, Matthew James, Zirwas
Publikováno v:
New England Journal of Medicine. 383:229-239
Systemic oral phosphodiesterase type 4 (PDE-4) inhibitors have been effective in the treatment of psoriasis. Roflumilast cream contains a PDE-4 inhibitor that is being investigated for the topical treatment of psoriasis.In this phase 2b, double-blind
Autor:
Marie-Louise Trotman, Kerry Cooper, Adrian R. Levy, Greta Lozano-Ortega, Mark Bensink, Geoffrey A. Block, Glenn M. Chertow, Sarah Goring, Heather Bennett, Nathalie Waser, Vasily Belozeroff
Publikováno v:
Journal of Comparative Effectiveness Research. 7:693-707
Aim: Randomized controlled trials (RCTs) with clinical outcomes are considered the gold standard for regulatory approval. However, by design they are only able to answer a small number of clinical questions. Other high-quality studies are required fo
Autor:
Waldemar Misiorowski, Marie-Louise Trotman, John P. Bilezikian, Andrey Gurevich, Liudmila Rozhinskaya, Henry G. Bone, Peter L. Lakatos, Miklós Tóth, Aliya Khan
Publikováno v:
European Journal of Endocrinology. 172:527-535
ObjectivePrimary hyperparathyroidism (PHPT) is diagnosed by the presence of hypercalcemia and elevated or nonsuppressed parathyroid hormone (PTH) levels. Although surgery is usually curative, some individuals fail or are unable or unwilling to underg
Autor:
Patrick S. Parfrey, Charles A. Herzog, Marie Louise Trotman, Kenneth W. Mahaffey, Bastian Dehmel, David C. Wheeler, Geoffrey A. Block, William G. Goodman, Jürgen Floege, Safa Abdalla, Ricardo Correa-Rotter, Sharon M. Moe, Yumi Kubo, Tilman B. Drüeke, Glenn M. Chertow, Gérard M. London
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Premature cardiovascular disease limits the duration and quality of life on long‐term hemodialysis. The objective of this study was to define the frequency of fatal and nonfatal cardiovascular events attributable to atherosclerotic and n
Autor:
Yumi Kubo, Karminder Gill, Patrick S. Parfrey, Marie-Louise Trotman, Glenn M. Chertow, Bastian Dehmel, Lulu Ren Sterling, Ioanna Gioni, Kenneth W. Mahaffey
Publikováno v:
Pharmaceutical statistics. 14(3)
Intention-to-treat (ITT) analysis is widely used to establish efficacy in randomized clinical trials. However, in a long-term outcomes study where non-adherence to study drug is substantial, the on-treatment effect of the study drug may be underestim
Autor:
David C. Wheeler, Marie Louise Trotman, Ricardo Correa-Rotter, Kenneth W. Mahaffey, Patrick S. Parfrey, Dennis Modafferi, Sharon M. Moe, Glenn M. Chertow, Geoffrey A. Block, Tilman B. Drüeke, Jürgen Floege, Charles A. Herzog, Bastian Dehmel, Gérard M. London, William G. Goodman
Publikováno v:
The Journal of clinical endocrinology and metabolism. 98(12)
The clinical course of secondary hyperparathyroidism (sHPT) in patients on hemodialysis is not well described, and the effect of the calcimimetic cinacalcet on disease progression is uncertain.Our objective was to describe 1) the clinical course of s