Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marie-Louise Loupart"'
Autor:
Steve Harrison, Sharron Vass, Marie-Louise Loupart, Margarete M. S. Heck, Sue A. Krause, Stefan Schoenfelder
Publikováno v:
Krause, S A, Loupart, M L, Vass, S, Schoenfelder, S, Harrison, S & Heck, M M S 2001, ' Loss of cell cycle checkpoint control in Drosophila Rfc4 mutants ', Molecular and Cellular Biology, vol. 21, no. 15, pp. 5156-5168 . https://doi.org/10.1128/MCB.21.15.5156-5168.2001
Two alleles of the Drosophila melanogaster Rfc4 (DmRfc4) gene, which encodes subunit 4 of the replication factor C (RFC) complex, cause striking defects in mitotic chromosome cohesion and condensation. These mutations produce larval phenotypes consis
Publikováno v:
Chromosome Research. 3:410-416
Fluorescence in situ hybridization (FISH) was used to establish the copy number of chromosome 1 in a set of nine breast tumours in which the chromosome had previously been shown to have undergone a variety of rearrangements by loss of heterozygosity
Autor:
John A.L. Armour, Marie-Louise Loupart, Jennifer Varley, William J. Brammar, Susan M. Adams, Rosemary A. Walker
Publikováno v:
Genes, Chromosomes and Cancer. 13:229-238
The analysis of loss of heterozygosity (LOH) in tumours can be a powerful tool for mapping the sites of tumour suppressor genes in the human genome. A panel of breast cancer patients was assembled as pairs of tumour and lymphocyte DNA samples and LOH
Autor:
John A.L. Armour, Rosemary A. Walker, Marie-Louise Loupart, William J. Brammar, Jennifer Varley, Susan M. Adams
Publikováno v:
Genes, Chromosomes and Cancer. 12:16-23
In order to characterise the role of chromosome 1 more fully in breast cancer, polymorphic markers mapping along the length of the whole chromosome were used to assess a panel of 71 tumour-lymphocyte pairs for allelic imbalance. Complex patterns of a
Publikováno v:
Loupart, M L, Krause, S A & Heck, M M S 2000, ' Aberrant replication timing induces defective chromosome condensation in Drosophila ORC2 mutants ', Current Biology, vol. 10, no. 24, pp. 1547-1556 . https://doi.org/10.1016/S0960-9822(00)00844-7
Background: The accurate duplication and packaging of the genome is an absolute prerequisite to the segregation of chromosomes in mitosis. To understand the process of cell-cycle chromosome dynamics further, we have performed the first detailed chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7633beb0b585352d8b5d903d739a0d
https://hdl.handle.net/20.500.11820/e58a1c3a-3332-4860-b4ff-d3a3cd5bda17
https://hdl.handle.net/20.500.11820/e58a1c3a-3332-4860-b4ff-d3a3cd5bda17
Autor:
Neville Cobbe, Enmoore Lin, Margarete M. S. Heck, William D. Warren, Terry L. Orr-Weaver, Paula A. Coelho, Michael J. McKay, Janice Y. Lee, Claudio E. Sunkel, Marie-Louise Loupart, Soren Steffensen
Publikováno v:
Warren, W D, Steffensen, S, Lin, E, Coelho, P, Loupart, M L, Cobbe, N, Lee, J Y, McKay, M J, Orr-Weaver, T, Heck, M M S & Sunkel, C E 2000, ' The Drosophila RAD21 cohesin persists at the centromere region in mitosis ', Current Biology, vol. 10, no. 22, pp. 1463-1466 . https://doi.org/10.1016/S0960-9822(00)00806-X
'Cohesin' is a highly conserved multiprotein complex thought to be the primary effector of sister-chromatid cohesion in all eukaryotes. Cohesin complexes in budding yeast hold sister chromatids together from S phase until anaphase, but in metazoans,
Publikováno v:
Chromosoma. 107(4)
A 4 Mb human mini-chromosome, DeltaDelta2, was transferred from Chinese hamster ovary (CHO) cells into a mouse L cell line. The mini-chromosome could be transferred intact into the L cells, with 112/119 clones maintaining a mini-chromosome of the sam
Publikováno v:
Current opinion in geneticsdevelopment. 6(3)
A mammalian artificial chromosome would enable analysis of the cis-acting DNA sequences necessary for mammalian chromosome function and would allow large numbers of genes in a defined sequence environment to be introduced into experimental animals, a
Publikováno v:
Nucleic acids research. 19(17)