Novel Tarantula Toxins for Subtypes of Voltage-Dependent Potassium Channels in the Kv2 and Kv4 Subfamilies

Autor: Michel Lazdunski, Pierre Escoubas, Terumi Nakajima, Marie-Louise Célérier, Sylvie Diochot

Publikováno v: Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2002, 62, pp.48-57
Molecular Pharmacology, 2002, 62, pp.48-57

Three novel peptides with the ability to inhibit voltage-dependent potassium channels in the shab (Kv2) and shal (Kv4) subfamilies were identified from the venom of the African tarantulas Stromatopelma calceata (ScTx1) and Heteroscodra maculata (HmTx

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ac8fca6138b9b04a08c1475f7d781b
https://doi.org/10.1124/mol.62.1.48

Multidimensional peptide fingerprinting by high performance liquid chromatography, capillary zone electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the identification of tarantula venom samples

Autor: Pierre Escoubas, Terumi Nakajima, Gerardo Corzo, Brian J. Whiteley, Marie-Louise Célérier, Charles P. Kristensen

Publikováno v: Rapid Communications in Mass Spectrometry. 12:1075-1084

The increased interest in spider venom toxins has made precise identification of venom samples necessary for reproducibility of biochemical and pharmacological studies. In the family Theraphosidae (Tarantulas), identification of specimens may be diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77979c881c3abcf95dbae96507c7ef10
https://doi.org/10.1002/(sici)1097-0231(19980831)12:16<1075::aid-rcm292>3.0.co

Peptide profiling by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry of the Lasiodora parahybana tarantula venom gland

Autor: Guewen Tournois, Marie-Louise Célérier, Max Goyffon, Christian Legros, Catherine Guette

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 47(6)

In order to establish a venom fingerprint and a peptide profile of the Lasiodora parahybana tarantula venom gland, we used conventional methods such as reversed phase liquid chromatography coupled to an electrospray-ionisation hybrid quadrupole time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdb0f03624aa1cfa4b74af5887e6d6e
https://pubmed.ncbi.nlm.nih.gov/16635501

An unusual cleavage reaction of a peptide observed during dithiotreitol and tris(2-carboxyethyl)phosphine reduction: application to sequencing of HpTx2 spider toxin using nanospray tandem mass spectrometry

Autor: Marie-Louise Célérier, Christian Legros, Catherine Guette

Publikováno v: Rapid communications in mass spectrometry : RCM. 18(12)

A recombinant peptidic spider toxin, HpTx2, was investigated directly by nanoelectrospray tandem mass spectrometry (MS/MS). This 30-residue toxin possesses a highly knotted structure with cystines arranged in close proximity. The low-energy collision

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793dac3b38a49e5aaceae1fe4da1e22
https://pubmed.ncbi.nlm.nih.gov/15174186

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and high-performance liquid chromatography study of quantitative and qualitative variation in tarantula spider venoms

Autor: Pierre, Escoubas, Gerardo, Corzo, Brian J, Whiteley, Marie-Louise, Célérier, Terumi, Nakajima

Publikováno v: Rapid communications in mass spectrometry : RCM. 16(5)

Animal venoms are important sources of novel pharmacological tools, useful in biochemical characterization of their receptors. Venom quality control, batch-to-batch homogeneity and high reproducibility of venom fractionation and toxin purification ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::56e3b59fdf188d0eb79c6d98f3da60e6
https://pubmed.ncbi.nlm.nih.gov/11857724