Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marie-José Plessis"'
Publikováno v:
Toxicology Mechanisms and Methods. 16:313-322
During the last years, much attention was focused on the measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dG) as a marker of oxidative DNA damage. Among various analytical techniques, the (32)P-postlabeling assay has been applied in determin
Autor:
Marie-José Plessis, François Périn, Christine Walczak, Evelyne Chenu, Andreas Volk, Carole D. Thomas
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine. 17:271-280
We previously performed MRI studies of HCC (hepatocellular carcinomas) in mice showing the feasibility of measuring a carbogen effect. In the present study carbogen response of the whole tumour was compared with growth characteristics during longitud
Publikováno v:
Environmental and Molecular Mutagenesis. 32:314-324
Mice of the XVIInc/Z and DBA/2N strains, which are responsive and nonresponsive, respectively, to the aryl hydrocarbon (Ah) receptor, were treated with the hepatocarcinogen 5,9-dimethyldibenzo[c,g]carbazole and their livers were examined by nuclease
Publikováno v:
Environmental toxicology. 20(3)
Microcystin-LR (MCYST-LR) and nodularin (NOD) are known as tumor promoters in experimental animals and so present potential health threats for humans. Although their hepatotoxic mechanisms have been very well documented, many other effects of these t
Publikováno v:
Mutation research. 564(1)
Microcystin-LR (MCYST-LR) and nodularin (NOD) produced by cyanobacteria are potent and specific hepatotoxins. The induction of free-radical formation, reduction of glutathione levels and induction of DNA damage are three major events found in rat hep
Autor:
Evelyne Chenu, Carole D. Thomas, Christine Walczak, Marie-José Plessis, François Périn, Andreas Volk
Publikováno v:
Magnetic resonance in medicine. 50(3)
A multifocal mouse liver tumor model chemically induced with 5,9-dimethyl-7H-dibenzo[c,g]carbazole was investigated by respiratory-triggered morphological and functional MRI (fMRI) at 4.7 Tesla. The model is characterized by the presence of two tumor
Autor:
Odette Périn-Roussel, François Périn, Marie-José Plessis, Danièle Taras-Valéro, François Zajdela
Publikováno v:
Environmental and molecular mutagenesis. 35(2)
The potent multitissue carcinogen 7H-dibenzo-[c,g]carbazole and nine methylated derivatives, synthesized on the basis of the positions in the parent compound that are involved in metabolism, were tested for their ability to induce sarcomas and hepati
Publikováno v:
Environmental and molecular mutagenesis. 25(3)
The recent observation of a high level of adducts in mitochondrial DNA (mtDNA) of cells exposed to chemical carcinogens aroused new interest in the hypothesis that carcinogen-induced damage in mitochondria plays a role in one or more stages of carcin
Publikováno v:
Cancer letters. 61(3)
The formation of DNA adducts was investigated in mouse fibroblasts from two different tissues — embryos and adult lung — after incubation with dibenzo[a,e]fluoranthene (DBF) or its major proximate metabolites. The nuclease P 1 modification of the
Autor:
Carole D. Thomas, Evelyne Chenu, Christine Walczak, Marie-José Plessis, François Perin, Andreas Volk
Publikováno v:
Magnetic Resonance in Medicine; Sep2003, Vol. 50 Issue 3, p522, 9p