Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marie-Jeanne Clement"'
Autor:
Krystel El Hage, Nicolas Babault, Olek Maciejak, Bénédicte Desforges, Pierrick Craveur, Emilie Steiner, Juan Carlos Rengifo-Gonzalez, Hélène Henrie, Marie-Jeanne Clement, Vandana Joshi, Ahmed Bouhss, Liya Wang, Cyril Bauvais, David Pastré
Publikováno v:
eLife, Vol 12 (2023)
RNA-protein interactions (RPIs) are promising targets for developing new molecules of therapeutic interest. Nevertheless, challenges arise from the lack of methods and feedback between computational and experimental techniques during the drug discove
Externí odkaz:
https://doaj.org/article/fba7b44d6c2f4d60b2a3433ce6ea930d
Akademický článek
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Autor:
Krystel El Hage, Nicolas Babault, Olek Maciejak, Bénédicte Desforges, Pierrick Craveur, Emilie Steiner, Juan Carlos Rengifo-Gonzalez, Hélène Henrie, Marie-Jeanne Clement, Vandana Joshi, Ahmed Bouhss, Liya Wang, Cyril Bauvais, David Pastré
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad604070ba5cb2bd19a23cc14dcd4edd
https://doi.org/10.7554/elife.80387.sa2
https://doi.org/10.7554/elife.80387.sa2
Autor:
Ilham Seffouh, Mélanie Bilong, Cédric Przybylski, Nesrine El Omrani, Salomé Poyer, Guillaume Lamour, Marie-Jeanne Clément, Rebecca-Joe Boustany, Evelyne Gout, Florence Gonnet, Romain R. Vivès, Régis Daniel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The human sulfatase HSulf-2 is one of only two known endosulfatases that play a decisive role in modulating the binding properties of heparan sulfate proteoglycans on the cell surface and in the extracellular matrix. Recently, HSulf-2 was sh
Externí odkaz:
https://doaj.org/article/74ccc652ff974500a6d2da80b5385266
Autor:
Aixiao Li, Ahmed Bouhss, Marie-Jeanne Clément, Cyril Bauvais, J. Paul Taylor, Guillaume Bollot, David Pastré
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
In recent years, RNA has gained traction both as a therapeutic molecule and as a therapeutic target in several human pathologies. In this review, we consider the approach of targeting RNA using small molecules for both research and therapeutic purpos
Externí odkaz:
https://doaj.org/article/22c47e5584934302a02e842601707265
Autor:
Anastasiia Samsonova, Krystel El Hage, Bénédicte Desforges, Vandana Joshi, Marie-Jeanne Clément, Guillaume Lambert, Hélène Henrie, Nicolas Babault, Pierrick Craveur, Rachid C. Maroun, Emilie Steiner, Ahmed Bouhss, Alexandre Maucuer, Dmitry N. Lyabin, Lev P. Ovchinnikov, Loic Hamon, David Pastré
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Samsonova et al. show a cooperative association of Lin28 and YB-1 for their target mRNA through their cold-shock domain, which is a conserved β-barrel structure that binds to single-stranded RNA. This study suggests that the association of Lin28 wit
Externí odkaz:
https://doaj.org/article/15258b4c3a3942419e49124926949c3e
Autor:
Juan Carlos Rengifo-Gonzalez, Krystel El Hage, Marie-Jeanne Clément, Emilie Steiner, Vandana Joshi, Pierrick Craveur, Dominique Durand, David Pastré, Ahmed Bouhss
Publikováno v:
eLife, Vol 10 (2021)
TDP-43 is a nuclear RNA-binding protein that forms neuronal cytoplasmic inclusions in two major neurodegenerative diseases, ALS and FTLD. While the self-assembly of TDP-43 by its structured N-terminal and intrinsically disordered C-terminal domains h
Externí odkaz:
https://doaj.org/article/de0ec8831ecd4f1da1a28a35d038e526
Autor:
Veli Bakalov, Roland Amathieu, Mohamed N. Triba, Marie-Jeanne Clément, Laura Reyes Uribe, Laurence Le Moyec, Ata Murat Kaynar
Publikováno v:
Metabolites, Vol 6, Iss 4, p 47 (2016)
Patients surviving sepsis demonstrate sustained inflammation, which has been associated with long-term complications. One of the main mechanisms behind sustained inflammation is a metabolic switch in parenchymal and immune cells, thus understanding m
Externí odkaz:
https://doaj.org/article/aab8f0f0098742098c8e742409bb7056