Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marie-Helène Seguelas"'
Autor:
Charlotte Rouzaud-Laborde, Naïma Hanoun, Ipek Baysal, Jean-Simon Rech, Céline Mias, Denis Calise, Pierre Sicard, Céline Frugier, Marie-Helène Seguelas, Angelo Parini, Nathalie Pizzinat
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e34893 (2012)
Serotonin (5-HT) regulates different cardiac functions by acting directly on cardiomyocytes, fibroblasts and endothelial cells. Today, it is widely accepted that activated platelets represent a major source of 5-HT. In contrast, a supposed production
Externí odkaz:
https://doaj.org/article/218a3d509eda4b8ea988cee16a2971d1
Autor:
Clement Karsenty, Celine Guilbeau-Frugier, Gaël Genet, Marie-Helene Seguelas, Philippe Alzieu, Olivier Cazorla, Alexandra Montagner, Yuna Blum, Caroline Dubroca, Julile Maupoint, Blandine Tramunt, Marie Cauquil, Thierry Sulpice, Sylvain Richard, Silvia Arcucci, Remy Flores-Flores, Nicolas Pataluch, Romain Montoriol, Pierre Sicard, Antoine Deney, Thierry Couffinhal, Jean-Michel Senard, Celine Galés
Publikováno v:
eLife, Vol 12 (2023)
The rod-shaped adult cardiomyocyte (CM) harbors a unique architecture of its lateral surface with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) with unknown role. Here, we investigated the development and functional ro
Externí odkaz:
https://doaj.org/article/4a1c47633a1c414d92ff3c8bf4e59cf3
Autor:
Stéphanie Ruiz, Fanny Vardon-Bounes, Marie Buléon, Céline Guilbeau-Frugier, Marie-Hélène Séguelas, Jean-Marie Conil, Jean-Pierre Girolami, Ivan Tack, Vincent Minville
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background In sepsis, the endothelial barrier becomes incompetent, with the leaking of plasma into interstitial tissues. VE-cadherin, an adherens junction protein, is the gatekeeper of endothelial cohesion. Kinins, released during sepsis, in
Externí odkaz:
https://doaj.org/article/344a68615d2c4ac3a4b74b7c4edeef26
Autor:
Lauriane Onfroy, Ségolène Galandrin, Stéphanie M. Pontier, Marie-Hélène Seguelas, Du N’Guyen, Jean-Michel Sénard, Céline Galés
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Biased agonism at G protein coupled receptors emerges as an opportunity for development of drugs with enhanced benefit/risk balance making biased ligand identification a priority. However, ligand biased signature, classically inferred from l
Externí odkaz:
https://doaj.org/article/46b62063d1b048b08dc910da43acf68d
Autor:
Céline Mias, Christelle Coatrieux, Colette Denis, Gaël Genet, Marie-Hélène Seguelas, Nathalie Laplace, Charlotte Rouzaud-Laborde, Denis Calise, Angelo Parini, Daniel Cussac, Atul Pathak, Jean-Michel Sénard, Céline Galés
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79068 (2013)
Sympathetic nervous system (SNS) plays a key role in cardiac homeostasis and its deregulations always associate with bad clinical outcomes. To date, little is known about molecular mechanisms regulating cardiac sympathetic innervation. The aim of the
Externí odkaz:
https://doaj.org/article/fab34a11a9a04ac5bbc46692810bfad4