Výsledky vyhledávání - "Marie-Hélène Rémy"

Functional Analysis of γ-Tubulin Complex Proteins Indicates Specific Lateral Association via Their N-terminal Domains

Autor: Laurence Haren, Andreas Merdes, Dorian Farache, Cécile Chemin, Marie-Hélène Rémy, Marine Chartrain, Alain Jauneau

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (44), pp.23112-23125. ⟨10.1074/jbc.M116.744862⟩

Microtubules are nucleated from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs). Small complexes (γTuSCs) comprise two molecules of γ-tubulin bound to the C-terminal domains of GCP2 and GCP3. γTuSCs a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85de0ed6d083c191f5fa12c479552ff
https://pubmed.ncbi.nlm.nih.gov/27660388

Zobrazit plný text záznamu

NMR Study of the Interaction between Zn(II) Ligated Bleomycin and Streptoalloteichus hindustanus Bleomycin Resistance Protein

Autor: Bernhard Brutscher, Martin Blackledge, Claudia Muhle-Goll, Dominique Marion, Jean-Michel Masson, Christophe Vanbelle, Marie-Hélène Rémy

Publikováno v: Biochemistry. 42:651-663

Bleomycin (Bm), a 1.4 kDa glycopeptide excreted by Streptomyces verticillus, is a natural antibacterial compound used in therapy as antineoplastic drug. To counteract its biological activity, cells have developed several resistance mechanisms, one of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000447215cc0a4be712f491a5778b364
https://doi.org/10.1021/bi0267341

Zobrazit plný text záznamu

Akademický článek

Virtual and biophysical screening targeting the γ-tubulin complex--a new target for the inhibition of microtubule nucleation.

Autor: Olivier Cala, Marie-Hélène Remy, Valérie Guillet, Andreas Merdes, Lionel Mourey, Alain Milon, Georges Czaplicki

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63908 (2013)

Microtubules are the main constituents of mitotic spindles. They are nucleated in large amounts during spindle assembly, from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs). With the aim of developing a

Externí odkaz: https://doaj.org/article/75705f809df6439785004efd0ffb3743

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání