Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Marie-Hélène Paclet"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Reactive oxygen species (ROS), produced by the phagocyte NADPH oxidase, NOX2, are involved in many leukocyte functions. An excessive or inappropriate ROS production can lead to oxidative stress and tissue damage. On the other hand, an absence of ROS
Externí odkaz:
https://doaj.org/article/3cabe2d3e2f54240a2ff996a18ec0f60
Autor:
Sylvie Berthier, Minh Vu Chuong Nguyen, Athan Baillet, Marc-André Hograindleur, Marie-Hélène Paclet, Benoît Polack, Françoise Morel
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40277 (2012)
S100A8 and S100A9 are two calcium binding Myeloid Related Proteins, and important mediators of inflammatory diseases. They were recently introduced as partners for phagocyte NADPH oxidase regulation. However, the precise mechanism of their interactio
Externí odkaz:
https://doaj.org/article/ae3f137f7fc74391a7988ed009fd69b0
Autor:
Bruno Marques, Lavinia Liguori, Marie-Hélène Paclet, Ana Villegas-Mendéz, Romy Rothe, Françoise Morel, Jean-Luc Lenormand
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e856 (2007)
BACKGROUND: Gp91(phox) is a transmembrane protein and the catalytic core of the NADPH oxidase complex of neutrophils. Lack of this protein causes chronic granulomatous disease (CGD), a rare genetic disorder characterized by severe and recurrent infec
Externí odkaz:
https://doaj.org/article/d87507d6175c4340b9ba9d8fd1c6db6a
Autor:
Xavier Romand, Benjamin Terrier, Athan Baillet, Philippe Gaudin, Loic Guillevin, Christian Pagnoux, Minh Vu Chuong, Marie Hélène Paclet
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Objective Serum calprotectin appears to be an interesting biomarker associated with renal vascular disease activity in antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV). The aim of this study was to assess whether serum calprotecti
Externí odkaz:
https://doaj.org/article/af3a8dfc5f814a07a9e869d256a098ca
Autor:
Bruno Fautrel, Xavier Romand, Athan Baillet, Margot Clapasson, Minh Vu Chuong, Marie Hélène Paclet
Publikováno v:
RMD Open, Vol 9, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/226e88e1689d450e953fe082f7df6fc4
Publikováno v:
Bioscience Reports. 42
Human kallikrein-kinin system (KKS) is a proteolytic cascade with two serine-protease zymogen couples (Factor XII and prekallikrein (PK) and their activated forms, FXIIa, PKa, respectively), releasing bradykinin by cleavage of native high-molecular-w
Autor:
Marie-Hélène Paclet, Bertrand Toussaint, Candice Trocme, Philippe Gaudin, Margot Clapasson, Xavier Romand, Minh Vu Chuong Nguyen, Chloé Bernardy, Anaïs Courtier, Athan Baillet
Publikováno v:
Revue du Rhumatisme
Revue du Rhumatisme, Elsevier, 2020, 87, pp.253-260. ⟨10.1016/j.rhum.2020.01.033⟩
Revue du Rhumatisme, Elsevier, 2020, 87, pp.253-260. ⟨10.1016/j.rhum.2020.01.033⟩
Resume La calprotectine est une proteine de liaison au calcium exprimee au site inflammatoire par les neutrophiles et les monocytes afin d’activer le systeme immunitaire inne. Grâce a cette caracteristique unique, elle constitue un bon indicateur
Publikováno v:
SSRN Electronic Journal.
Autor:
Candice Trocme, Anaïs Courtier, Bertrand Toussaint, Minh Vu Chuong Nguyen, Philippe Gaudin, Xavier Romand, Margot Clapasson, Marie-Hélène Paclet, Chloé Bernardy, Athan Baillet
Publikováno v:
Joint Bone Spine
Joint Bone Spine, Elsevier Masson, 2019, 86, pp.691-698. ⟨10.1016/j.jbspin.2019.01.003⟩
Joint Bone Spine, Elsevier Masson, 2019, 86, pp.691-698. ⟨10.1016/j.jbspin.2019.01.003⟩
Calprotectin is a calcium binding protein produced by neutrophils and monocytes locally at the site of inflammation in order to trigger the innate immunity receptors. This unique characteristic makes it a good proxy for evaluation of local inflammati
Autor:
Miklós Geiszt, Françoise Morel, Melinda Zana, Ágnes Donkó, Marie-Hélène Paclet, Zalán Péterfi, Hajnal A. Kovács, Stanislas Morand, Thomas L. Leto, Balázs Enyedi, Zsuzsanna Tóth
Publikováno v:
Free Radical Biology and Medicine. 116:41-49
The p22phox protein is an essential component of the phagocytic- and inner ear NADPH oxidases but its relationship to other Nox proteins is less clear. We have studied the role of p22phox in the TGF-β1-stimulated H2O2 production of primary human and