Evaluation of thrombin generation assay in factor XI deficiency

Autor: Sabine Brunel, Guillaume Feugray, Marielle Fresel, Virginie Barbay, Véronique Le Cam Duchez, Pierre Chamouni, Paul Billoir, Marie Hélène Chrétien, Fiston Kasonga

Publikováno v: Clinica Chimica Acta. 523:348-354

Factor XI (FXI) deficiency is characterized by a lack of correlation between FXI plasma levels and the occurrence of hemorrhagic events. The main objective of our study was to determine whether thrombin generation assay (TGA) could be used to assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bfd9c3d480102b15e87e86f08e92a4
https://doi.org/10.1016/j.cca.2021.10.021

Factor XII deficiency evaluated by thrombin generation assay

Autor: Marie Hélène Chrétien, Pierre Chamouni, Paul Billoir, Fiston Kasonga, Virginie Barbay, Sabine Brunel, Marielle Fresel, Guillaume Feugray, Véronique Le Cam Duchez

Publikováno v: Clinical biochemistry. 100

INTRODUCTION Coagulation factor XII (FXII) plays a role in thrombin generation, fibrinolysis, inflammation, angiogenesis, chemotaxis and diapedesis. FXII deficiency is not associated with bleeding risk unlike other coagulation factors. MATERIALS/METH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37b770b0b3750b06e66f2a226500087
https://pubmed.ncbi.nlm.nih.gov/34843733

Quel bilan devant une haemolacria ? À propos d’un cas et revue de la littérature

Autor: Guillaume Feugray, Marielle Fresel, Marie Hélène Chrétien, Paul Billoir, V. Le Cam Duchez

Publikováno v: La Revue De Médecine Interne
La Revue De Médecine Interne, Elsevier, 2020, 41, pp.339-342. ⟨10.1016/j.revmed.2019.12.007⟩
La Revue de Médecine Interne
La Revue de Médecine Interne, Elsevier, 2020, 41, pp.339-342. ⟨10.1016/j.revmed.2019.12.007⟩

Resume Introduction L’haemolacria est un syndrome hemorragique rare caracterise par l’ecoulement de larmes de sang. Les etiologies de cette pathologie sont variees, les plus frequentes sont l’inflammation, l’infection ou encore des laceration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbc359e4212b10a24b0f279f1d8d481
https://hal.archives-ouvertes.fr/hal-03490235

Thrombin generation profile in non-thrombotic factor V Leiden carriers

Autor: Paul Billoir, Véronique Le Cam Duchez, Thomas Duflot, Marie Hélène Chrétien, Virginie Barbay, Marielle Fresel

Publikováno v: Journal of thrombosis and thrombolysis. 47(3)

Factor V Leiden (FVL) mutation is the most common genetic risk factor for venous thromboembolism. In families with a history of thrombosis, FVL can be present in 18%. Thrombin generation test is commonly used as an evaluation tool of thrombotic risk.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf44beaa91160219d51b3c81316355b9
https://pubmed.ncbi.nlm.nih.gov/30701464

Management of dabigatran after overdosage: two case reports and suggestions for monitoring

Autor: Virginie Barbay, Steven Grangé, Véronique Le Cam Duchez, Déborah Boyer, Paul Billoir, Marielle Fresel, Christophe Girault, Marie Hélène Chrétien

Publikováno v: Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 29(7)

Bleeding is the main complication of anticoagulant treatments as dabigatran etexilate. In patients with atrial fibrillation, dabigatran, at certain doses, has been associated with similar rates of stroke and embolism, and a lower rate of major hemorr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249050a16eb273ec4c6b5f98ba33c05a
https://pubmed.ncbi.nlm.nih.gov/30045050