Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Marie-Francoise Bordes"'
Autor:
Laurence Millet, Angelina Besse, Stéphanie Tissandié, Gernot Zech, Marie-Francoise Bordes, Alain Badorc, Lassalle Gilbert, Valerie Fossey, Jean-Pascal Herault, Frédérique Dol, Christophe Boldron, Benjamin Gau, Christophe Briot, Nathalie Delesque, Anne-Marie Pflieger, Françoise Bono, Xavier Yvon, Marc Nazaré, Guillaume Barre, Tristan Rousseaux, Jean-Marc Herbert, Sandrine Bonnet-Lignon, Jerome Meneyrol, Pierre Savi
Publikováno v:
Journal of medicinal chemistry. 57(17)
In the search of a potential backup for clopidogrel, we have initiated a HTS campaign designed to identify novel reversible P2Y12 antagonists. Starting from a hit with low micromolar binding activity, we report here the main steps of the optimization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291b64860ee2ed44163c467111c8fa67
https://pubmed.ncbi.nlm.nih.gov/25075638
https://pubmed.ncbi.nlm.nih.gov/25075638
Autor:
Jean-Marc Herbert, Maurice Petitou, Marie-Francoise Bordes, Alain Badorc, Jean-Pierre Maffrand, Lalé A, de Cointet P, Andre Bernat, Pierre Savi
Publikováno v:
Journal of Medicinal Chemistry. 40:3393-3401
The platelet fibrinogen receptor GpIIb-IIIa is curently considered a target of choice for drugs used in the prevention and treatment of thrombosis. Ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl)imino]met...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04845bef979001a03632e1287bff817d
https://doi.org/10.1021/jm970240y
https://doi.org/10.1021/jm970240y