Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marie-France Paugam"'
Autor:
Frédérique Barbosa, Frédéric Revah, Dragos Horvath, Laurent Coussy, Rafael Gozalbes, Marie-France Paugam, Eric Nicolai, Catherine Rolland
Publikováno v:
Journal of Medicinal Chemistry. 48:6563-6574
A QSAR model accounting for "average" G-protein-coupled receptor (GPCR) binding was built from a large set of experimental standardized binding data (1939 compounds systematically tested over 40 different GPCRs) and applied to the design of a library
Autor:
Catherine Rolland, Dragos Horvath, Laurent Coussy, Rafael Gozalbes, Frédéric Revah, Nicolas Froloff, Marie-France Paugam, Eric Nicolaï, Frédérique Barbosa, Boryeu Mao
Publikováno v:
QSAR & Combinatorial Science. 24:508-516
An innovative approach has been developed in order to construct new GPCR focused libraries. Experimental binding data generated in house from 1939 diverse drug and drug-like compounds on 40 GPCR targets were used to develop and validate a "global GPC
Autor:
Marie-France Paugam, Stephen J. Gardiner, Tracey A. Munro, Jennifer A. Riggs, Bradley D. Smith
Publikováno v:
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry. 32:121-131
A number of methods are described to facilitate the transport of monosaccharides, catecholamines, and amino acids through bulk liquid membranes, supported liquid membranes and plasticized cellulose triacetate membranes. Transport is mediated by carri
Autor:
Feike de Jong, David N. Reinhoudt, Bradley D. Smith, Marie-France Paugam, Lysander A. J. Chrisstoffels, Jeffrey T. Bien
Publikováno v:
Journal of the American Chemical Society, 118(41), 9820-9825. American Chemical Society
A series of crown boronic acids, 1-4, were synthesized and studied as carriers for catecholamine transport through bulk liquid membranes (BLMs) and supported liquid membranes (SLMs). Carrier 1 greatly facilitated the transport of primary catecholamin
Publikováno v:
Journal of the American Chemical Society. 116:8895-8901
The ability of phenylboronic acid, [3-(1-adamantylcarboxamido)phenyl]boronic acid, and diphenylborinic acid to extract and transport p-nitrophenyl [beta]-D-glucopyranoside (glucoside), p-nitrophenyl [beta]-D-galactopyranoside (galactoside), and p-nit
Publikováno v:
The Journal of Organic Chemistry. 59:2724-2728
The ability of phenylboronic acid and 3-(1-adamantylcarboxamido)phenylboronic acid to mediate the transport of p-nitrophenyl β-D-glucopyranoside (glucoside), p-nitrophenyl β-D-galactopyranoside (galactoside), p-nitrophenyl β-D-mannopyranoside (man
Publikováno v:
Tetrahedron Letters. 34:7841-7844
A carrier admixture of phenylboronic acid and ionophore (cryptand or crown ether) simultaneously co-transports p-nitrophenyl β-glucopyranoside, M+ and OH−, through a liquid organic membrane. The transport mechanism involves the apparent self-assem
Autor:
Bradley D. Smith, Marie-France Paugam
Publikováno v:
Tetrahedron Letters. 34:3723-3726
Phenylboronic acid simultaneously co-transports the ribonucleoside, uridine, and fluoride ion through an organic liquid membrane. The transport mechanism involves self-assembly of a lipophilic ion-pair comprising of phenylboronic acid, flouride ion,
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :165-169
N,N′-Bis(chloroacetyl)indigo [N,N′-bis(chloroacetyl)-2,2′-bi-indolinylidene-3,3′-dione], (3) and N-chloroacetylindigo (N-chloroacetyl-2,2′-bi-indolinylidene-3,3′-dione), (4) were synthesized, their solid state molecular structures charact
Publikováno v:
ChemInform. 24