Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marie-Clotilde Bernard"'
Autor:
Marie-Clotilde Bernard, Emilie Bazin, Nadine Petiot, Katia Lemdani, Sylvie Commandeur, Cécile Verdelet, Sylvie Margot, Vladimir Perkov, Manon Ripoll, Marie Garinot, Sophie Ruiz, Florence Boudet, Bachra Rokbi, Jean Haensler
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 794-806 (2023)
The use of modified nucleosides is an important approach to mitigate the intrinsic immunostimulatory activity of exogenous mRNA and to increase its translation for mRNA therapeutic applications. However, for vaccine applications, the intrinsic immuno
Externí odkaz:
https://doaj.org/article/84ac57ce98d7454485767fa0e4db3183
Autor:
Marie-Clotilde Bernard, Florence Boudet, Andrea-Clemencia Pineda-Peña, Françoise Guinet-Morlot
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The World Health Organization protocol for rabies post-exposure prophylaxis (PEP) recommends extensive wound washing, immediate vaccination, and administration of rabies immunoglobulin (RIG) in severe category III exposures. Some studies hav
Externí odkaz:
https://doaj.org/article/041f2f0776f0400082ae8763fecea72a
Autor:
Marie-Clotilde Bernard, Joanna Waldock, Sylvie Commandeur, Lea Strauß, Claudia Maria Trombetta, Serena Marchi, Fan Zhou, Serge van de Witte, Peter van Amsterdam, Sammy Ho, Katja Hoschler, Vladimir Lugovtsev, Jerry P. Weir, Emanuele Montomoli, Rebecca J. Cox, Othmar G. Engelhardt, Damien Friel, Ralf Wagner, Thierry Ollinger, Sophie Germain, Hanna Sediri-Schön
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Current vaccination strategies against influenza focus on generating an antibody response against the viral haemagglutination surface protein, however there is increasing interest in neuraminidase (NA) as a target for vaccine development. A critical
Externí odkaz:
https://doaj.org/article/c7eb7830935240038d837eec99dca889
Autor:
Marie-Clotilde Bernard, Véronique Barban, Fabrine Pradezynski, Aymeric de Montfort, Robert Ryall, Catherine Caillet, Patricia Londono-Hayes
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121518 (2015)
HSV-2 vaccine is needed to prevent genital disease, latent infection, and virus transmission. A replication-deficient mutant virus (dl5-29) has demonstrated promising efficacy in animal models of genital herpes. However, the immunogenicity, protectiv
Externí odkaz:
https://doaj.org/article/2da7164c3101452cb4c3d58b226dfdd7
Publikováno v:
Journal of applied toxicology : JATREFERENCES.
Herpes simplex virus type 2 (HSV-2) is the most common cause of genital disease worldwide. The development of an effective HSV-2 vaccine would significantly impact global health based on the psychological distress caused by genital herpes for some in
Autor:
Marie-Clotilde Bernard, Isabelle Legastelois, Isabelle Peubez, Sylvie Margot, Sandrine Deloire, Sophie Buffin, Sergio Marco, David Poncet, Premkumar Dinadayala, Corinne Pion
Publikováno v:
Vaccine. 38:7905-7915
Hemagglutinin, the major surface protein of influenza viruses, was recombinantly expressed in eukaryotic cells as a monomer instead of its native trimer, and was only immunogenic when administered with an adjuvant [Pion et al. 2014]. In order to mult
Autor:
Karine Broudic, Alexander Amberg, Markus Schaefer, Hans-Peter Spirkl, Marie-Clotilde Bernard, Paul Desert
Publikováno v:
Toxicology and applied pharmacology. 451
mRNA vaccines hold tremendous potential in disease control and prevention for their flexibility with respect to production, application, and design. Recent breakthroughs in mRNA vaccination would have not been possible without major advances in lipid
Autor:
Manon Ripoll, Marie-Clotilde Bernard, Céline Vaure, Emilie Bazin, Sylvie Commandeur, Vladimir Perkov, Katia Lemdani, Marie-Claire Nicolaï, Patrick Bonifassi, Antoine Kichler, Benoit Frisch, Jean Haensler
Publikováno v:
Biomaterials. 286:121570
The mRNA vaccine technology has promising applications to fight infectious diseases as demonstrated by the licensing of two mRNA-based vaccines, Comirnaty® (Pfizer/BioNtech) and Spikevax® (Moderna), in the context of the Covid-19 crisis. Safe and e
Autor:
Sébastien Carayol, Eric Richier, Jon Heinrichs, Marie-Clotilde Bernard, Florence Boudet, Valerie Lecouturier, Catherine C. Berry
Publikováno v:
Vaccine. 37(20)
After decades of inconsequential infections, and sporadic outbreaks in the Asia-Pacific region between 2007 and 2013, Zika virus caused a widespread epidemic in South America in 2015 that was complicated by severe congenital infections. After the WHO
Autor:
Nicolas Jackson, Francisco Maldonado-Arocho, Valerie Lecouturier, Ana P. Goncalvez, Raul C. Gomila, Harold Kleanthous, Diaz Fernando Martin, Nicolas Burdin, John Catalan, Maryann Giel-Moloney, Simon Delagrave, Ray Oomen, Konstantin V. Pugachev, Jon Heinrichs, Marie-Clotilde Bernard, Yves Girerd-Chambaz
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Zika virus (ZIKV) is an emerging mosquito-borne pathogen representing a global health concern. It has been linked to fetal microcephaly and other birth defects and neurological disorders in adults. Sanofi Pasteur has engaged in the development of an