Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marie-Claude Guillemin"'
Publikováno v:
Clinical Cancer Research. 15:6321-6326
Acute promyelocytic leukemia (APL) is characterized by a specific t(15;17) chromosomal translocation that yields the PML/RARA fusion gene. Clinically, besides chemotherapy, two drugs induce clinical remissions: retinoic acid (RA) and arsenic trioxide
Publikováno v:
Hématologie. 15:015-018
Auteur(s) : Rihab Nasr1, Marie-Claude Guillemin2, Philippe Rousselot3, Hugues de The2 1Departement de medecine interne, universite americaine de Beyrouth, Hamra, Beyrouth, Liban 2Equipe labellisee no 11, Ligue nationale contre le cancer, Universite d
Autor:
J. Michael Bishop, Scott C. Kogan, Eric Lagasse, David B. Shultz, Irving L. Weissman, Valérie Lallemand-Breitenbach, Marie-Claude Guillemin, Diane E. Brown, Bao-Tran H. Truong
Publikováno v:
Journal of Experimental Medicine. 193:531-544
The promyelocytic leukemia retinoic acid receptor α (PMLRARα) chimeric protein is associated with acute promyelocytic leukemia (APL). PMLRARα transgenic mice develop leukemia only after several months, suggesting that PMLRARα does not by itself c
Autor:
Valérie Lallemand-Breitenbach, Marie-Claude Guillemin, Anne Janin, Marie-Thérèse Daniel, Laurent Degos, Scott C. Kogan, J. Michael Bishop, Hugues de Thé
Publikováno v:
The Journal of Experimental Medicine
In acute promyelocytic leukemia (APL) patients, retinoic acid (RA) triggers differentiation while arsenic trioxide (arsenic) induces both a partial differentiation and apoptosis. Although their mechanisms of action are believed to be distinct, these
Autor:
Pier Paolo Pandolfi, Macarena Robledo-Sarmiento, Valérie Lallemand-Breitenbach, Philippe Rousselot, Rihab Nasr, Bernard Gourmel, Hassan Soilihi, Caroline Berthier, Jun Zhu, Laurent Peres, Omar Ferhi, Marie-Claude Guillemin, Dominique Vitoux, Cécile Rochette-Egly
Publikováno v:
Nature Medicine
Nature Medicine, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. 〈10.1038/nm.1891〉
Nature Medicine, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. 〈10.1038/nm.1891〉
International audience; Retinoic acid and arsenic trioxide target the protein stability and transcriptional repression activity of the fusion oncoprotein PML-RARA, resulting in regression of acute promyelocytic leukemia (APL). Phenotypically, retinoi
Autor:
Fabien Guidez, Sarah Parks, Henna Wong, Jelena V. Jovanovic, Ashley Mays, Amanda F. Gilkes, Kenneth I. Mills, Marie-Claude Guillemin, Robin M. Hobbs, Pier Paolo Pandolfi, Hugues de Thé, Ellen Solomon, David Grimwade
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(47)
Leukemia-associated chimeric oncoproteins often act as transcriptional repressors, targeting promoters of master genes involved in hematopoiesis. We show that CRABPI (encoding cellular retinoic acid binding protein I) is a target of PLZF, which is fu
Autor:
Marie-Claude Guillemin, Emmanuel Raffoux, Dominique Vitoux, Scott Kogan, Hassane Soilihi, Valérie Lallemand-Breitenbach, Jun Zhu, Anne Janin, Marie-Thérèse Daniel, Bernard Gourmel, Laurent Degos, Hervé Dombret, Michel Lanotte, Hugues de Thé
Publikováno v:
The Journal of experimental medicine, vol 196, iss 10
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Differentiation therapy for acute myeloid leukemia uses transcriptional modulators to reprogram cancer cells. The most relevant clinical example is acute promyelocytic leukemia (APL), which responds dramatically to either retinoic acid (RA) or arseni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672947da1ee7a661a104cd2218ed05c4
https://escholarship.org/uc/item/227528s7
https://escholarship.org/uc/item/227528s7
Autor:
Joelle Tobaly-Tapiero, Patricia Bittoun, Manuel Neves, Marie-Claude Guillemin, Charles-Henri Lecellier, Francine Puvion-Dutilleul, Bernard Gicquel, Stephan Zientara, Marie-Louise Giron, Hugues de Thé, Ali Saïb
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2000, 74 (9), pp.4064-73
Journal of Virology, American Society for Microbiology, 2000, 74 (9), pp.4064-73
Foamy viruses (FVs) are complex retroviruses which have been isolated from different animal species including nonhuman primates, cattle, and cats. Here, we report the isolation and characterization of a new FV isolated from blood samples of horses. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8031ce9c221bdc19c7c243a7fedfc87c
https://hal.archives-ouvertes.fr/hal-02106474
https://hal.archives-ouvertes.fr/hal-02106474
Autor:
Jocelyne Valla, Marie-Lou Giron, Ali Saïb, J. Peries, Marie-Claude Guillemin, M. Canivet, Manuel Neves
Publikováno v:
Virology. 228(2)
Human foamy virus (HFV) belongs to the spumaretrovirus group of the Retroviridae taxonomic family. Attempts to associate HFV or other foamy viruses to a specific pathology still remain unsuccessful. However, viral gene expression as well as tissue-sp
Autor:
Chantal Andre, Marie-Claude Guillemin, Jun Zhu, Marcel H.M. Koken, Frédérique Quignon, Laurence Herve, Mounira K. Chelbi-Alix, Daniel Dhumeaux, Zeng-Yi Wang, Laurent Degos, Zhu Chen, Hugues de The
Publikováno v:
Experimental cell research. 229(2)
Acute promyelocytic leukemia (APL) is specifically associated to a t(15; 17) translocation which fuses a gene encoding a nuclear receptor for retinoic acid, RARalpha, to a previously unknown gene PML. The PML protein is localized in the nucleus on a