Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marie-Claude Guillemin"'
Publikováno v:
Clinical Cancer Research. 15:6321-6326
Acute promyelocytic leukemia (APL) is characterized by a specific t(15;17) chromosomal translocation that yields the PML/RARA fusion gene. Clinically, besides chemotherapy, two drugs induce clinical remissions: retinoic acid (RA) and arsenic trioxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429f517c703b9fd2e958f76c8bf1e063
https://doi.org/10.1158/1078-0432.ccr-09-0209
https://doi.org/10.1158/1078-0432.ccr-09-0209
Publikováno v:
Hématologie. 15:015-018
Auteur(s) : Rihab Nasr1, Marie-Claude Guillemin2, Philippe Rousselot3, Hugues de The2 1Departement de medecine interne, universite americaine de Beyrouth, Hamra, Beyrouth, Liban 2Equipe labellisee no 11, Ligue nationale contre le cancer, Universite d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5239baf05a9f49a37a68c7f373e3ce03
https://doi.org/10.1684/hma.2009.0318
https://doi.org/10.1684/hma.2009.0318
Autor:
J. Michael Bishop, Scott C. Kogan, Eric Lagasse, David B. Shultz, Irving L. Weissman, Valérie Lallemand-Breitenbach, Marie-Claude Guillemin, Diane E. Brown, Bao-Tran H. Truong
Publikováno v:
Journal of Experimental Medicine. 193:531-544
The promyelocytic leukemia retinoic acid receptor α (PMLRARα) chimeric protein is associated with acute promyelocytic leukemia (APL). PMLRARα transgenic mice develop leukemia only after several months, suggesting that PMLRARα does not by itself c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49030b955e443f685db3d1c6e26d57d0
https://doi.org/10.1084/jem.193.4.531
https://doi.org/10.1084/jem.193.4.531
Autor:
Valérie Lallemand-Breitenbach, Marie-Claude Guillemin, Anne Janin, Marie-Thérèse Daniel, Laurent Degos, Scott C. Kogan, J. Michael Bishop, Hugues de Thé
Publikováno v:
The Journal of Experimental Medicine
In acute promyelocytic leukemia (APL) patients, retinoic acid (RA) triggers differentiation while arsenic trioxide (arsenic) induces both a partial differentiation and apoptosis. Although their mechanisms of action are believed to be distinct, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a821358906655adb5d4295a4131d7630
https://doi.org/10.1084/jem.189.7.1043
https://doi.org/10.1084/jem.189.7.1043
Autor:
Pier Paolo Pandolfi, Macarena Robledo-Sarmiento, Valérie Lallemand-Breitenbach, Philippe Rousselot, Rihab Nasr, Bernard Gourmel, Hassan Soilihi, Caroline Berthier, Jun Zhu, Laurent Peres, Omar Ferhi, Marie-Claude Guillemin, Dominique Vitoux, Cécile Rochette-Egly
Publikováno v:
Nature Medicine
Nature Medicine, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. 〈10.1038/nm.1891〉
Nature Medicine, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. 〈10.1038/nm.1891〉
International audience; Retinoic acid and arsenic trioxide target the protein stability and transcriptional repression activity of the fusion oncoprotein PML-RARA, resulting in regression of acute promyelocytic leukemia (APL). Phenotypically, retinoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22618929217386a94e273b214059d7b9
https://pubmed.ncbi.nlm.nih.gov/19111876
https://pubmed.ncbi.nlm.nih.gov/19111876
Autor:
Fabien Guidez, Sarah Parks, Henna Wong, Jelena V. Jovanovic, Ashley Mays, Amanda F. Gilkes, Kenneth I. Mills, Marie-Claude Guillemin, Robin M. Hobbs, Pier Paolo Pandolfi, Hugues de Thé, Ellen Solomon, David Grimwade
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(47)
Leukemia-associated chimeric oncoproteins often act as transcriptional repressors, targeting promoters of master genes involved in hematopoiesis. We show that CRABPI (encoding cellular retinoic acid binding protein I) is a target of PLZF, which is fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1d5bf90d4974f8267932747b054c68
https://pubmed.ncbi.nlm.nih.gov/18000064
https://pubmed.ncbi.nlm.nih.gov/18000064
Autor:
Marie-Claude Guillemin, Emmanuel Raffoux, Dominique Vitoux, Scott Kogan, Hassane Soilihi, Valérie Lallemand-Breitenbach, Jun Zhu, Anne Janin, Marie-Thérèse Daniel, Bernard Gourmel, Laurent Degos, Hervé Dombret, Michel Lanotte, Hugues de Thé
Publikováno v:
The Journal of experimental medicine, vol 196, iss 10
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Differentiation therapy for acute myeloid leukemia uses transcriptional modulators to reprogram cancer cells. The most relevant clinical example is acute promyelocytic leukemia (APL), which responds dramatically to either retinoic acid (RA) or arseni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672947da1ee7a661a104cd2218ed05c4
https://escholarship.org/uc/item/227528s7
https://escholarship.org/uc/item/227528s7
Autor:
Jocelyne Valla, Marie-Lou Giron, Ali Saïb, J. Peries, Marie-Claude Guillemin, M. Canivet, Manuel Neves
Publikováno v:
Virology. 228(2)
Human foamy virus (HFV) belongs to the spumaretrovirus group of the Retroviridae taxonomic family. Attempts to associate HFV or other foamy viruses to a specific pathology still remain unsuccessful. However, viral gene expression as well as tissue-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358f963aa0ee3e08f78ddd14ff181dd2
https://pubmed.ncbi.nlm.nih.gov/9123833
https://pubmed.ncbi.nlm.nih.gov/9123833
Autor:
Chantal Andre, Marie-Claude Guillemin, Jun Zhu, Marcel H.M. Koken, Frédérique Quignon, Laurence Herve, Mounira K. Chelbi-Alix, Daniel Dhumeaux, Zeng-Yi Wang, Laurent Degos, Zhu Chen, Hugues de The
Publikováno v:
Experimental cell research. 229(2)
Acute promyelocytic leukemia (APL) is specifically associated to a t(15; 17) translocation which fuses a gene encoding a nuclear receptor for retinoic acid, RARalpha, to a previously unknown gene PML. The PML protein is localized in the nucleus on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ab4f0ed431c01e7298b18b8da95792
https://pubmed.ncbi.nlm.nih.gov/8986606
https://pubmed.ncbi.nlm.nih.gov/8986606
Autor:
Francine Puvion-Dutilleul, Laetizia Venturini, Marie-Claude Guillemin, Hugues de Thé, Edmond Puvion
Publikováno v:
Experimental cell research. 221(2)
We investigated the intranuclear distribution of PML and Sp100 in HeLa cells at the ultrastructural level and examined their relocalization in response to herpes simplex virus type 1 (HSV-1) infection. In the absence of infection, we observed that bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaced02ac60630ddf77cd13822f3dfe
https://pubmed.ncbi.nlm.nih.gov/7493645
https://pubmed.ncbi.nlm.nih.gov/7493645