Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Marie-Claude Drolet"'
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Aortic valve regurgitation (AR) results in left ventricle (LV) volume overload (VO) leading to its dilation and hypertrophy (H). We study a rat model of severe AR induced by puncturing one or two leaflets using a catheter. Most of
Externí odkaz:
https://doaj.org/article/961e466ed4924207aebdd1967a0a59dd
Publikováno v:
FEBS Open Bio, Vol 8, Iss 10, Pp 1624-1635 (2018)
Cardiac hypertrophy (CH) is an important and independent predictor of morbidity and mortality. Through expression profiling, we recently identified a subset of genes (Dhrs7c, Decr, Dhrs11, Dhrs4, Hsd11b1, Hsd17b10, Hsd17b8, Blvrb, Pecr), all of which
Externí odkaz:
https://doaj.org/article/aebf7bb00875482eab8659b90eb472ee
Autor:
Catherine Beaumont, Élisabeth Walsh-Wilkinson, Marie-Claude Drolet, Élise Roussel, Marie Arsenault, Jacques Couet
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Aortic valve regurgitation (AR) imposes a volume overload (VO) to the left ventricle (LV). Male rats with a pathological heart overload usually progress more quickly towards heart failure than females. We examined whether a sexual dimorphism
Externí odkaz:
https://doaj.org/article/19273e3852134af8ad0171b0556572c3
Autor:
Elisabeth Walsh-Wilkinson, Catherine Beaumont, Marie-Claude Drolet, Ève-Marie Roy, Charlie Le Houillier, Jonathan Beaudoin, Marie Arsenault, Jacques Couet
Publikováno v:
PeerJ, Vol 7, p e7924 (2019)
Aortic valve regurgitation (AR) can result in heart failure from chronic overloading of the left ventricle (LV). Little is known of the role of estrogens in the LV responses to this condition. The aim of the study was to compare LV remodeling in fema
Externí odkaz:
https://doaj.org/article/4c030f88184947d3bbc638faa6abbba8
Autor:
Élisabeth Walsh-Wilkinson, Marie-Claude Drolet, Charlie Le Houillier, Ève-Marie Roy, Marie Arsenault, Jacques Couet
Publikováno v:
PeerJ, Vol 7, p e7461 (2019)
Background. Men and women differ in their susceptibility to cardiovascular disease, though the underlying mechanism has remained elusive. Heart disease symptoms, evolution and response to treatment are often sex-specific. This has been studied in ani
Externí odkaz:
https://doaj.org/article/4da74235677b444b818537e4f033a769
Autor:
Alexandre P Garneau, Andrée-Anne Marcoux, Micheline Noël, Rachelle Frenette-Cotton, Marie-Claude Drolet, Jacques Couet, Richard Larivière, Paul Isenring
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154398 (2016)
Inactivation of Kcc3 in a mixed 129/Sv×C57BL/6 mouse background has been previously found to increase systemic blood pressure (BP) through presumed neurogenic mechanisms. Yet, while this background is generally not considered ideal to investigate th
Externí odkaz:
https://doaj.org/article/8fe7d09f3b414bb191a0aa6dad766178
Autor:
Catherine Gérard, Xiao Xiao, Mohammed Filali, Zoé Coulombe, Marie Arsenault, Jacques Couet, Juan Li, Marie-Claude Drolet, Pierre Chapdelaine, Amina Chikh, Jacques P Tremblay
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Friedreich ataxia (FRDA) is a genetic disease due to increased repeats of the GAA trinucleotide in intron 1 of the frataxin gene. This mutation leads to a reduced expression of frataxin. We have produced an adeno-associated virus (AAV)9 coding for hu
Externí odkaz:
https://doaj.org/article/045e7f6aef3643b880e41e531514bf84
Publikováno v:
FEBS Open Bio
Cardiac hypertrophy (CH) is an important and independent predictor of morbidity and mortality. Through expression profiling, we recently identified a subset of genes (Dhrs7c, Decr, Dhrs11, Dhrs4, Hsd11b1, Hsd17b10, Hsd17b8, Blvrb, Pecr), all of which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40025fab28457f18fdb627fb35d89a3
http://europepmc.org/articles/PMC6168690
http://europepmc.org/articles/PMC6168690
Autor:
Jacques Couet, Mathieu Laplante, Stéphanie Miard, Yohan Bossé, Pascale Blais-Lecours, Julie Lacombe, Frédéric Picard, Denis Richard, Julie S. Lefebvre, Marie Claude Drolet, Philippe St-Pierre, Sandrine Sallé-Lefort, Mathieu Ferron, Sophie Carter, Emilie Lavoie-Charland, Fernando F. Anhê, Alexandre Caron, Yves Deshaies, André Marette, David Marsolais
Publikováno v:
Diabetes. 67:1285-1296
The current demographic shift toward an aging population has led to a robust increase in the prevalence of age-associated metabolic disorders. Interestingly, recent studies have demonstrated that the etiology of obesity-related insulin resistance dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adae52003d86d8bc9b3f6474c6c62fca
https://doi.org/10.2337/db17-0558
https://doi.org/10.2337/db17-0558
Autor:
Marie-Claude Drolet, J. Luis Guerrero, Patrick Mathieu, Marie-Annick Clavel, Jonathan Beaudoin, Claudia Côté-Laroche, Ons Marsit, Marie Arsenault, Marie-Chloé Boulanger, Dae-Hee Kim, Robert A. Levine, Philipp E. Bartko, Elena Aikawa, Joyce Bischoff, Mark D. Handschumacher, Sandra Hadjadj, Marc-André Bouchard, Jacques Couet, Marine Clisson, Philippe Pibarot
Publikováno v:
Journal of the American College of Cardiology. 75(4)
Background Mitral leaflet enlargement has been identified as an adaptive mechanism to prevent mitral regurgitation in dilated left ventricles (LVs) caused by chronic aortic regurgitation (AR). This enlargement is deficient in patients with functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc33ac12651502ae1a5e2378a90ee58
https://pubmed.ncbi.nlm.nih.gov/32000952
https://pubmed.ncbi.nlm.nih.gov/32000952