Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marie-Claude Burgevin"'
Autor:
Corinne Lafon, Amélie Dommergue, Thomas Rooney, Dominique Lesuisse, Thy Phuong Hieu Luc, Anne Olivier, Pierre-Yves Abecassis, Luc Even, Véronique Taupin, Patrick Lardenois, Xavier Vigé, Marie-Noëlle Castel, Florian Auger, Yannick Evanno, Andre Malanda, Marie-Claude Burgevin, Pascal Barneoud, Céline Cegarra, Antonio Almario, Joanna Tsi, Pascale Brunel, Jean-Francois Peyronel, Danielle De-Peretti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:929-932
In the course of a programme aimed at identifying Nurr1/NOT agonists for potential treatment of Parkinson’s disease, a few hits from high throughput screening were identified and characterized. A combined optimization pointed to a very narrow and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da24f03facfdd36275110ac060ed5915
https://doi.org/10.1016/j.bmcl.2019.01.024
https://doi.org/10.1016/j.bmcl.2019.01.024
Autor:
Benoît Pinson, Irène Ceballos-Picot, Renaud Morales, Robert Barouki, Bertrand Daignan-Fornier, G.M. Pinon, Anne Olivier-Bandini, Françoise Chesney, Jessica Huyet, Franck Augé, Christelle Saint-Marc, Roland Lupoli, Abdul Rauf Siddiqi, Pierre Nioche, Mohammad Ozeir, Jean-Marc Remy, Jean-Francois Gibert, Marie-Claude Burgevin
Publikováno v:
Cell Chemical Biology
Cell Chemical Biology, Cell Press, 2018, 25 (6), pp.666-676.e4. ⟨10.1016/j.chembiol.2018.02.011⟩
Cell Chemical Biology, Cell Press, 2018, 25 (6), pp.666-676.e4. ⟨10.1016/j.chembiol.2018.02.011⟩
Summary Phosphoribosyltransferases catalyze the displacement of a PRPP α-1′-pyrophosphate to a nitrogen-containing nucleobase. How they control the balance of substrates/products binding and activities is poorly understood. Here, we investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd7c0c1339d7dfe2220644525a69f0c
https://pubmed.ncbi.nlm.nih.gov/29576532
https://pubmed.ncbi.nlm.nih.gov/29576532
Autor:
Gilles Dutruc-Rosset, Sébastien Maignan, Alain Chevalier, Frank Halley, Thomas Rooney, Matthias K. Dreyer, Dominique Lesuisse, Gilles Tiraboschi, Dominique Quarteronet, Philippe Bertrand, Marie-Claude Burgevin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1985-1989
From an HTS hit, a series of potent and selective inhibitors of GSK3β have been designed based on a Cdk2-homology model and with the help of several crystal structures of the compounds within Cdk2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fd7bd1858589017041fe68fdcfe9e7
https://doi.org/10.1016/j.bmcl.2010.01.114
https://doi.org/10.1016/j.bmcl.2010.01.114
Publikováno v:
British Journal of Pharmacology. 125:1421-1428
1 Intracellular calcium concentrations in individual rat motoneurones in enriched primary cultures were measured by Indo-1 fluorimetry. 2 Motoneurones in the cultures were characterized morphometrically and by cholineacetyltransferase immunocytochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::798c6aa91aac29f6f9b7237e3b266a9c
https://doi.org/10.1038/sj.bjp.0702207
https://doi.org/10.1038/sj.bjp.0702207
Autor:
François Petitet, Christian Czech, Marie-Claude Burgevin, Adam Doble, Dominique Quarteronet, Laurence Delalonde, Laurent Pradier
Publikováno v:
Europe PubMed Central
We examined the regional and cellular distribution of presenilin-1 gene expression in the rat brain by in situ hybridization. Microscopic analysis demonstrated that presenilin-1 mRNA is predominantly expressed in areas such as the occipital cortex, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2b64c0b08f3b3e59c4983289b23dd6
https://doi.org/10.1097/00001756-199611040-00036
https://doi.org/10.1097/00001756-199611040-00036
Autor:
Jean-Claude Depezay, Marie-Claude Burgevin, Evelyne James-Surcouf, Frédéric Herman, Michel Barreau, Marc Vuilhorgne, Yves Le Merrer, Serge Mignani, Guy Pantel, Lydie Poitout, Jean-Charles Blanchard, Dominique Damour, Adam Doble
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1667-1672
Based on molecular modelling studies of Sandostatin®, sugar-based derivatives I-VI were prepared as potential non-peptide mimics of somatostatin/Sandostatin®. These compounds displaced 3-[ 125 I]-Tyr 11 -SRIF-14 from the somatostatin receptor on me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df46447f1422d7ad74f5bf1d34fadfa
https://doi.org/10.1016/0960-894x(96)00289-2
https://doi.org/10.1016/0960-894x(96)00289-2
Autor:
Jean Marie Miquet, Marie-Claude Burgevin, M. Daniel, C. Malgouris, Mireille Meunier, Francoise Bordier, Colette Peny, Gabrielle Durand, Adam Doble, Jean-Charles Blanchard, Alain Boireau, Thierry Chevet, Serge Mignani, Patrick Jimonet
Publikováno v:
European Journal of Pharmacology. 300:237-246
The NMDA antagonist and neuroprotective effects of RPR 104632 (2H-1,2,4-benzothiadiazine-1-dioxide-3-carboxylic acid), a new benzothiadiazine derivative, with affinity for the glycine site of the NMDA receptor-channel complex are described. RPR 10463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9da49b43d63294dec22001f209d4ea4
https://doi.org/10.1016/0014-2999(95)00780-6
https://doi.org/10.1016/0014-2999(95)00780-6
Publikováno v:
Journal of Molecular Neuroscience. 6:33-41
We have cloned and expressed a rat cDNA, designated GALR1-rat, that encodes a galanin receptor based on homology, pharmacology, and anatomical criteria. This cDNA was isolated from a rat brain cDNA library. The nucleotide sequence of the cloned recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d298601ffd7cbac264b62d8c528c75
https://doi.org/10.1007/bf02736757
https://doi.org/10.1007/bf02736757
Autor:
Y. Le Merrer, Serge Mignani, Jean-Charles Blanchard, L. Poitout, Marc Vuilhorgne, Guy Pantel, J.‐C. Depezay, Michel Barreau, Marie-Claude Burgevin, Dominique Damour, A. Doble, Evelyne James-Surcouf, Frédéric Herman
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c492d5292ed332c12b0cb19f26c10594
https://doi.org/10.1002/chin.199646239
https://doi.org/10.1002/chin.199646239
Autor:
Guy Pantel, J.‐C. Blanchard, Richard Labaudiniere, Dominique Damour, Adam Doble, Michel Barreau, Serge Mignani, Marie-Claude Burgevin
Publikováno v:
ChemInform. 30
Synthesis of novel spirocyclic lactam peptidomimetics of the binding domain of somatostatin from commercially available D, L-methionine is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b7b61a292e867124547b8114200e2a
https://doi.org/10.1002/chin.199905163
https://doi.org/10.1002/chin.199905163