Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment.

Autor: Pierre Mazot, Alex Cazes, Florent Dingli, Joffrey Degoutin, Théano Irinopoulou, Marie-Claude Boutterin, Bérangère Lombard, Damarys Loew, Bengt Hallberg, Ruth Helen Palmer, Olivier Delattre, Isabelle Janoueix-Lerosey, Marc Vigny

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33581 (2012)

Recently, activating mutations of the full length ALK receptor, with two hot spots at positions F1174 and R1275, have been characterized in sporadic cases of neuroblastoma. Here, we report similar basal patterns of ALK phosphorylation between the neu

Externí odkaz: https://doaj.org/article/9d6429e92bd6409f8569ebcb91d45e53

FAK dimerization controls its kinase-dependent functions at focal adhesions

Autor: Katarzyna W. Walkiewicz, Stefan T. Arold, Álvaro Ortega, Jean-Antoine Girault, Laïla Gasmi, Paul G. Leonard, Nicolas Gervasi, Karen Brami-Cherrier, Gress Kadaré, Bastien Seantier, Diana A. Arsenieva, Marie Claude Boutterin, Tahar Bouceba

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2014, 33 (4), pp.356-370. ⟨10.1002/embj.201386399⟩
EMBO Journal, 2014, 33 (4), pp.356-370. ⟨10.1002/embj.201386399⟩
The EMBO Journal

International audience; Abstract Focal adhesion kinase (FAK) controls adhesion-dependent cell motility, survival, and proliferation. FAK has kinase-dependent and kinase-independent functions, both of which play major roles in embryogenesis and tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce87f5d4ba2fe387f28c87f98b393147
https://hal.archives-ouvertes.fr/hal-01537170

Differential Localization of the Cystic Fibrosis Transmembrane Conductance Regulator in Normal and Cystic Fibrosis Airway Epithelium

Autor: Edith Puchelle, C Fuchey, Wilfried Dalemans, Jacky Jacquot, Dominique Gaillard, Jocelyne Hinnrasky, Andrea Pavirani, Dominique Dreyer, Marie-Claude Boutterin, Dominique Ploton

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 7:485-491

Deletion of the amino acid residue Phe 508 of the cystic fibrosis transmembrane conductance regulator (CFTR) protein represents the most common mutation identified in cystic fibrosis (CF) patients. A monoclonal and a polyclonal antibody directed agai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896461f4dbcf30ac17c1b8f339289c31
https://doi.org/10.1165/ajrcmb/7.5.485

PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation

Autor: Gress Kadaré, Jean-Antoine Girault, Etienne Formstecher, Madeleine Toutant, Marie-Claude Boutterin, Michèle Carnaud, Jean-Christophe Corvol

Publikováno v: The Journal of biological chemistry. 278(48)

Focal adhesion kinase (FAK) is a protein tyrosine kinase enriched in focal adhesions, which plays a critical role in integrin-dependent cell motility and survival. The crucial step in its activation is autophosphorylation on Tyr-397, which promotes t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b10e40468fa0c98af53acd28be4468
https://pubmed.ncbi.nlm.nih.gov/14500712

Developmental tissue expression and phylogenetic conservation of stathmin, a phosphoprotein associated with cell regulations

Autor: André Sobel, Marie-Claude Boutterin, H Peyro-Saint-Paul, J Koppel, V Doye

Publikováno v: Juraj Koppel
Scopus-Elsevier

Stathmin is a 19-kDa phosphoprotein presumably involved in regulations of cell proliferation, differentiation, and functions as an intracellular relay for extracellular signals activating diverse second messenger pathways. Antisera prepared against t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3621e742778856435bb1f9798b976c
https://pubmed.ncbi.nlm.nih.gov/2303475