Review of the Geant4-DNA Simulation Toolkit for Radiobiological Applications at the Cellular and DNA Level

Autor: Ioanna Kyriakou, Dousatsu Sakata, Hoang Ngoc Tran, Yann Perrot, Wook-Geun Shin, Nathanael Lampe, Sara Zein, Marie Claude Bordage, Susanna Guatelli, Carmen Villagrasa, Dimitris Emfietzoglou, Sébastien Incerti

Publikováno v: Cancers
Cancers, MDPI, 2022, 14 (1), pp.35. ⟨10.3390/cancers14010035⟩
Cancers, Vol 14, Iss 35, p 35 (2022)

Simple Summary A brief description of the methodologies to simulate ionizing radiation transport in biologically relevant matter is presented. Emphasis is given to the physical, chemical, and biological models of Geant4-DNA that enable mechanistic ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ab60fe6672cc0fe5ef379ca7c22816
https://hal.archives-ouvertes.fr/hal-03501436

ASSESSING THE CONTRIBUTION OF CROSS-SECTIONS TO THE UNCERTAINTY OF MONTE CARLO CALCULATIONS IN MICRO- AND NANODOSIMETRY

Autor: Heidi Nettelbeck, B. Heide, Marie-Claude Bordage, Carmen Villagrasa, M. Bueno, E. Gargioni, Hans Rabus, S. Chiriotti, Alessio Parisi, M.U. Bug

Publikováno v: Radiation Protection Dosimetry. 183:11-16

Within EURADOS Working Group 6 'Computational Dosimetry', the micro and nanodosimetry task group 6.2 has recently conducted a Monte Carlo (MC) exercise open to participants around the world. The aim of this exercise is to quantify the contribution to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfbb295028fb2f02bcb1c3a03dd757f
https://doi.org/10.1093/rpd/ncy240

Electron transport in DNA bases: An extension of the Geant4-DNA Monte Carlo toolkit

Autor: Alessandro Genoni, Giovanni Macetti, Sara A. Zein, Ziad Francis, Marie-Claude Bordage, Sebastien Incerti, Claude Dal Cappello, Wook Geun Shin

Publikováno v: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Elsevier, 2021, 488, pp.70-82. ⟨10.1016/j.nimb.2020.11.021⟩
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2021, 488, pp.70-82. ⟨10.1016/j.nimb.2020.11.021⟩

The purpose of this work is to extend the Geant4-DNA Monte Carlo toolkit to include electron interactions with the four DNA bases using a set of cross sections recently implemented in Geant-DNA CPA100 models and available for liquid water. Electron i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4435b4f795625104415c0cd8e3b2b0
https://hal.univ-lorraine.fr/hal-03103859

Fully integrated Monte Carlo simulation for evaluating radiation induced DNA damage and subsequent repair using Geant4-DNA

Autor: Ivan Petrović, Dousatsu Sakata, Marie-Claude Bordage, Ioanna Kyriakou, Vladimir Ivanchenko, Taku Inaniwa, Sebastien Incerti, Nathanael Lampe, Aleksandra Ristić-Fira, Susanna Guatelli, Dimitris Emfietzoglou, Oleg Belov, M. Karamitros, Wook Geun Shin

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.20788. ⟨10.1038/s41598-020-75982-x⟩

Ionising radiation induced DNA damage and subsequent biological responses to it depend on the radiation’s track-structure and its energy loss distribution pattern. To investigate the underlying biological mechanisms involved in such complex system,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2eb2b64931133e71ff282311d8265d
http://europepmc.org/articles/PMC7695857

Geant4 electromagnetic physics progress

Autor: Ivana Hřivnáčová, Denis Bernard, Mihaly Novak, Dmitri Konstantinov, Helmut Burkhardt, Vladimir Grichine, Paolo Dondero, Wook Geun Shin, O Kadri, A. Mantero, Susanna Guatelli, Sebastien Incerti, Dousatsu Sakata, José Ramos-Méndez, L. Urbán, Vladimir Ivanchenko, Alexander Bagulya, Marie-Claude Bordage, D Sawkey, Marilena Bandieramonte, Igor Semeniouk, M. Maire, Luciano Pandola, Samer Bakr, Ngoc Hoang Tran, Ioanna Kyriakou

Publikováno v: EPJ Web of Conferences, Vol 245, p 02009 (2020)
EPJ Web of Conferences
EPJ Web Conference
24th International Conference on Computing in High Energy and Nuclear Physics (CHEP 2019)
24th International Conference on Computing in High Energy and Nuclear Physics (CHEP 2019), Nov 2019, Adelaide, Australia. pp.02009, ⟨10.1051/epjconf/202024502009⟩

International audience; The Geant4 electromagnetic (EM) physics sub-packages are a component of LHC experiment simulations. During long shutdown 2 for LHC, these packages are under intensive development and we report progress of EM physics in Geant4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229a01db34ff15d04b61bca37c63cc31
https://www.epj-conferences.org/articles/epjconf/pdf/2020/21/epjconf_chep2020_02009.pdf