Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marie-Claire Kratzer"'
Autor:
Katharina Puzik, Veronika Tonnier, Isabell Opper, Antonia Eckert, Lu Zhou, Marie-Claire Kratzer, Ferdinand le Noble, Gerd Ulrich Nienhaus, Dietmar Gradl
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract The activation of distinct branches of the Wnt signaling network is essential for regulating early vertebrate development. Activation of the canonical Wnt/β-catenin pathway stimulates expression of β-catenin-Lef/Tcf regulated Wnt target ge
Externí odkaz:
https://doaj.org/article/5d0d6020b0a44fca92dd365bddb89771
Autor:
Rahul P. Langhe, Tetyana Gudzenko, Michael Bachmann, Sarah F. Becker, Carina Gonnermann, Claudia Winter, Genevieve Abbruzzese, Dominique Alfandari, Marie-Claire Kratzer, Clemens M. Franz, Jubin Kashef
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Cadherins are typically involved in cell-cell adhesion, however cadherin-11 promotes cell migration through an undefined mechanism. Langhe et al.show that cadherin-11 mediates adhesion to the cell matrix at focal adhesions through interaction with sy
Externí odkaz:
https://doaj.org/article/5bb0959474d3492ab98085db22a78b7c
Publikováno v:
Gene Expression Patterns. 32:18-27
Guanine nucleotide exchange factors (GEFs) activate Rho GTPases by accelerating their GDP/GTP exchange. Trio and its paralog Kalirin (Kalrn) are unique members of the Rho-GEFs that harbor three catalytic domains: two functional GEF domains and a seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b9522841121650f62be58cbbfba90b
https://doi.org/10.1016/j.gep.2019.02.004
https://doi.org/10.1016/j.gep.2019.02.004
Autor:
Anita Grund, Anne M. Merks, Annette Borchers, Jakub Harnoš, Sarah F. S. Becker, Vítězslav Bryja, Marie-Claire Kratzer, Jubin Kashef, Klaudia Giehl
Publikováno v:
Development (Cambridge, England). 147(10)
Directional migration during embryogenesis and tumor progression faces the challenge that numerous external signals need to converge to precisely control cell movement. The Rho guanine exchange factor (GEF) Trio is especially well suited to relay sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0987676fefcc3ddcf05efba3b38dadda
https://pubmed.ncbi.nlm.nih.gov/32366678
https://pubmed.ncbi.nlm.nih.gov/32366678
Autor:
Ferdinand le Noble, Veronika Tonnier, Dietmar Gradl, Isabell Opper, Marie-Claire Kratzer, Antonia F. Eckert, Katharina Puzik, Lu Zhou, Gerd Ulrich Nienhaus
Publikováno v:
Scientific reports, 9 (1), Article No.15645
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
The activation of distinct branches of the Wnt signaling network is essential for regulating early vertebrate development. Activation of the canonical Wnt/β-catenin pathway stimulates expression of β-catenin-Lef/Tcf regulated Wnt target genes and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da61974336903a693a6ab6c52f77c5bd
https://doi.org/10.1038/s41598-019-52218-1
https://doi.org/10.1038/s41598-019-52218-1
Publikováno v:
Developmental biology. 411(2)
The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population, which migrates directionally on defined routes throughout the embryo, contributing to facial structures including cartilage, bone and ganglia. Cadherin-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ad8914dc09d47fc8649dbcb36ed6e8
https://pubmed.ncbi.nlm.nih.gov/26879760
https://pubmed.ncbi.nlm.nih.gov/26879760
Autor:
Nicoletta Crosta, Stefan Bräse, Sonja Halbedl, Jessica Zippert, Dietmar Gradl, Karolin Rahm, Kye-Simeon Masters, Marie-Claire Kratzer
Publikováno v:
FEBS Letters. (5):522-527
Large scale screening of libraries consisting of natural and small molecules led to the identification of many small molecule inhibitors repressing Wnt/β-Catenin signaling. However, targeted synthesis of novel Wnt pathway inhibitors has been rarely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e40f90cafe59c7015fa53fb6a86d1c0