Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Marie-Claire Goulet"'
Autor:
Marie-Claire Goulet, Linda Gaudreau, Marielle Gagné, Anne-Marie Maltais, Ann-Catherine Laliberté, Gilbert Éthier, Nicole Bechtold, Michèle Martel, Marc-André D’Aoust, André Gosselin, Steeve Pepin, Dominique Michaud
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Data are scarce about the influence of basic cultural conditions on growth patterns and overall performance of plants used as heterologous production hosts for protein pharmaceuticals. Higher plants are complex organisms with young, mature, and senes
Externí odkaz:
https://doaj.org/article/104a8b7d304c4ca48f75afa96cc25230
Autor:
Philippe V Jutras, Carla Marusic, Chiara Lonoce, Carole Deflers, Marie-Claire Goulet, Eugenio Benvenuto, Dominique Michaud, Marcello Donini
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167086 (2016)
The overall quality of recombinant IgG antibodies in plants is dramatically compromised by host endogenous proteases. Different approaches have been developed to reduce the impact of endogenous proteolysis on IgGs, notably involving site-directed mut
Externí odkaz:
https://doaj.org/article/29d2ff07321b4003b813b47f345eb40f
Publikováno v:
Toxins, Vol 4, Iss 6, Pp 455-475 (2012)
Transgenic plants expressing combinations of microbial or plant pesticidal proteins represent a promising tool for the efficient, durable control of herbivorous insects. In this review we describe current strategies devised for the heterologous co-ex
Externí odkaz:
https://doaj.org/article/70e14df25c6d479fa2de5588d5736914
Autor:
Stéphanie Robert, Moustafa Khalf, Marie-Claire Goulet, Marc-André D'Aoust, Frank Sainsbury, Dominique Michaud
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70203 (2013)
The expression of clinically useful proteins in plants has been bolstered by the development of high-yielding systems for transient protein expression using agroinfiltration. There is a need now to know more about how host plant development and metab
Externí odkaz:
https://doaj.org/article/4a94360a42474169b7d090b0eb8e4a74
Autor:
Iauhenia Isayenka, Juan Duque‐Yate, Marie‐Claire Goulet, Dominique Michaud, Carole Beaulieu, Nathalie Beaudoin
Publikováno v:
Plant Pathology. 72:100-111
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e62a9d174a4590e3be0900e6db8f856
https://doi.org/10.1111/ppa.13650
https://doi.org/10.1111/ppa.13650
Publikováno v:
The FEBS Journal. 289:1827-1841
Protein engineering approaches have been proposed to improve the inhibitory properties of plant cystatins against herbivorous arthropod digestive proteases, generally involving the site-directed mutagenesis of functionally relevant amino acids or the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72c88b9ac9bc35bb38060bd04548d7e
https://doi.org/10.1111/febs.16288
https://doi.org/10.1111/febs.16288
Protein engineering approaches have been proposed to improve the inhibitory properties of plant cystatins towards herbivorous pest digestive Cys proteases, typically involving sequence alterations in the inhibitory loops and/or N-terminal trunk of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a129b0c93921c38ef7456b735ae5af
https://doi.org/10.1101/2022.02.26.482125
https://doi.org/10.1101/2022.02.26.482125
Autor:
Rachel Tardif, Marie-Claire Goulet, Pierre-Olivier Lavoie, Frank Sainsbury, Louis-Philippe Hamel, Marc-André D'Aoust, Philippe V. Jutras, Dominique Michaud
Publikováno v:
Journal of Proteome Research. 19:106-118
Partial neutralization of the Golgi lumen pH by the ectopic expression of influenza virus M2 proton channel is useful to stabilize acid-labile recombinant proteins in plant cells, but the impact of pH gradient mitigation on host cellular functions ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4eeb0a8d4b59fdaaa794da33b3be1b7
https://doi.org/10.1021/acs.jproteome.9b00409
https://doi.org/10.1021/acs.jproteome.9b00409
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2139
Protease inhibitors of the cystatin protein superfamily show potential in plant protection for the control of herbivorous pests. Here, we describe a cystatin activity-based profiling procedure for the selection of potent cystatin candidates, using si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0b65ac688eed6abf01d51a9c7617ea8
https://pubmed.ncbi.nlm.nih.gov/32462599
https://pubmed.ncbi.nlm.nih.gov/32462599
Publikováno v:
Methods in Molecular Biology ISBN: 9781071605271
Protease inhibitors of the cystatin protein superfamily show potential in plant protection for the control of herbivorous pests. Here, we describe a cystatin activity–based profiling procedure for the selection of potent cystatin candidates, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92fe6daff7131a7ac932ae13cbed5492
https://doi.org/10.1007/978-1-0716-0528-8_26
https://doi.org/10.1007/978-1-0716-0528-8_26