Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Marie-Claire Lasne"'
Autor:
Stéphane Leleu, Xavier Franck, Vincent Bizet, Marie-Claire Lasne, Agathe Boulangé, Jérôme Baudoux, Jacques Rouden, Valerie Lefebvre
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 2011 (22), pp.4170-4175. ⟨10.1002/ejoc.201100120⟩
European Journal of Organic Chemistry (22), 4170-4175. (2011)
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 2011 (22), pp.4170-4175. ⟨10.1002/ejoc.201100120⟩
European Journal of Organic Chemistry (22), 4170-4175. (2011)
International audience; Treatment of 2-methoxycarbonyl- (or 3-cyano-)allyl acetoacetates with a tertiary amine or triphenylphosphane afforded α-methylene γ-substituted δ-keto esters (or nitrile) in satisfactory yields. Various bases and nucleophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c769535f8b2919ef2b90a9116708e77b
https://doi.org/10.1002/ejoc.201100120
https://doi.org/10.1002/ejoc.201100120
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6667-6670
(−)-9-Fluorocytisine, (−)-9-methylcytisine and (−)-9-trifluoromethylcytisine were synthesized from the natural product (−)-cytisine. 9-Methyl and 9-trifluoromethyl cytisines display a remarkable affinity at the α4β2 nicotinic receptor subty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21170a5940b24730cc3e44b6476c998
https://doi.org/10.1016/j.bmcl.2010.09.017
https://doi.org/10.1016/j.bmcl.2010.09.017
Publikováno v:
Green Chem.. 12:252-259
Aiming at the development of green and efficient C–C bond formations (aldol and Mannich reactions), the decarboxylative nucleophilic addition of malonic acid half ester to imines or aldehydes under mild metal-free conditions was studied. A careful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c5b8848400773eab8c21b4fafa99782
https://doi.org/10.1039/b915681j
https://doi.org/10.1039/b915681j
Autor:
Juliette Martin, Jean-Christophe Plaquevent, Marie-Claire Lasne, Jacques Maddaluno, Jacques Rouden
Publikováno v:
European Journal of Organic Chemistry. 2009:5414-5422
A detailed study of the deracemization of pipecolic acid amides is reported. Enantioselective protonation of the lithium enolates of these amides with use of commercially available ephedrines led to enantiomeric excesses (ee values) higher than 99 %.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94106db2668e2d3e4fa64d1c35a65165
https://doi.org/10.1002/ejoc.200900726
https://doi.org/10.1002/ejoc.200900726
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 8:497-522
Tumor development leading to cancer is a complex process involving several steps. Among them, angiogenesis, ie growth of new tumor induced blood vessels is one of the most important therapeutic targets in the search for anticancer agents. One point w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082aa3d08b14a76a1ab24db381753584
https://doi.org/10.2174/187152008784533026
https://doi.org/10.2174/187152008784533026
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2008, 10 (5), pp.1029-32. ⟨10.1021/ol8000975⟩
Organic Letters, American Chemical Society, 2008, 10 (5), pp.1029-32. ⟨10.1021/ol8000975⟩
International audience; Mannich-type reactions of a glyoxylate imine with carbonyl compounds catalyzed by 3-trifluoromethanesulfonamidopyrrolidine proceed with high yields and anti-stereoselectivity. The catalyst is easily prepared and the transforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fda5492943c8f1af2cf0b2d7da344d3
https://doi.org/10.1021/ol8000975
https://doi.org/10.1021/ol8000975
Publikováno v:
Synthesis. 2007:3406-3410
An efficient approach to bis([1,2,4]-oxadiazol)benzaldehydes as well as the corresponding mono-benzaldehyde derivatives has been developed starting from benzamidoxime, which is readily obtained from 4-cyanobenzaldehyde. All these new compounds were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c811ee27226f282bb9ec5fb2a07d1e9
https://doi.org/10.1055/s-2007-990834
https://doi.org/10.1055/s-2007-990834
Autor:
Anne Harrison-Marchand, Jacques Maddaluno, Franck Paté, Hassan Oulyadi, Marie-Claire Lasne, Catherine Fressigné, Jean-Yves Valnot, Nicolas Duguet
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2007, 72 (18), pp.6982-6991. ⟨10.1021/jo071160x⟩
Journal of Organic Chemistry, American Chemical Society, 2007, 72 (18), pp.6982-6991. ⟨10.1021/jo071160x⟩
The effect of lithium halides on the enantioselectivity of the addition of methyllithium on o-tolualdehyde, in the presence of chiral lithium amides derived from chiral 3-aminopyrrolidines (3APLi), has been investigated. The enantiomeric excess of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc96054eadf2df37ada9b4b87058fdc4
https://doi.org/10.1021/jo071160x
https://doi.org/10.1021/jo071160x
Autor:
Ludovic Jean, Audrey Solgadi, Marie‐Claire Lasne, Jacques Courtieu, Jacques Rouden, Abdelkrim Meddour
Publikováno v:
Tetrahedron: Asymmetry. 18:1511-1516
It is shown that lyotropic liquid crystal mixtures made of poly-γ-benzyl- l -glutamate (PBLG) dissolved in N , N -dimethylformamide (DMF) are efficient anisotropic NMR solvents to distinguish the enantiomers of chiral amines through the effects of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e82647e63f99d447a7dc00929f21ee4f
https://doi.org/10.1016/j.tetasy.2007.06.018
https://doi.org/10.1016/j.tetasy.2007.06.018