Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marie-Christine Cumont"'
Autor:
Mireille Laforge, Laure Campillo-Gimenez, Valérie Monceaux, Marie-Christine Cumont, Bruno Hurtrel, Jacques Corbeil, John Zaunders, Carole Elbim, Jérôme Estaquier
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002087 (2011)
Subversion or exacerbation of antigen-presenting cells (APC) death modulates host/pathogen equilibrium. We demonstrated during in vitro differentiation of monocyte-derived macrophages and monocyte-derived dendritic cells (DCs) that HIV sensitizes the
Externí odkaz:
https://doaj.org/article/0d9479ce59ce42359ce7cea759fab099
Autor:
Philippe V Afonso, Simona Ozden, Marie-Christine Cumont, Danielle Seilhean, Luis Cartier, Payam Rezaie, Sarah Mason, Sophie Lambert, Michel Huerre, Antoine Gessain, Pierre-Olivier Couraud, Claudine Pique, Pierre-Emmanuel Ceccaldi, Ignacio A Romero
Publikováno v:
PLoS Pathogens, Vol 4, Iss 11, p e1000205 (2008)
The blood-brain barrier (BBB), which forms the interface between the blood and the cerebral parenchyma, has been shown to be disrupted during retroviral-associated neuromyelopathies. Human T Lymphotropic Virus (HTLV-1) Associated Myelopathy/Tropical
Externí odkaz:
https://doaj.org/article/18a1c5576acb44d599ed07d8996ee779
Autor:
Guido Silvestri, Julie Garibal, Vasco Rodrigues, Alain Pruvost, Shahul Mouhamad, Mireille Laforge, Valérie Monceaux, Jérôme Estaquier, Anna Senik, Bruno Hurtrel, Henintsoa Rabezanahary, Ricardo Silvestre, Anabela Cordeiro-da-Silva, Laure Campillo-Gimenez, Marie-Christine Cumont
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2018, 128 (4), pp.1627-1640. ⟨10.1172/JCI95127⟩
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2018, 128 (4), pp.1627-1640. ⟨10.1172/JCI95127⟩
Apoptosis has been proposed as a key mechanism responsible for CD4+ T cell depletion and immune dysfunction during HIV infection. We demonstrated that Q-VD-OPH, a caspase inhibitor, inhibits spontaneous and activation-induced death of T cells from SI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a722532b12bdd83ff678a61fe5e8c8
https://europepmc.org/articles/PMC5873886/
https://europepmc.org/articles/PMC5873886/
Autor:
Marie-Christine Cumont, Hassen Kared, Michaela Müller-Trutwin, Carole Elbim, Valérie Monceaux, Jérôme Estaquier, Ousmane M. Diop, Laure Campillo-Gimenez, John Zaunders, Michèle Fay, Bruno Hurtrel, Maria Leite-de-Moraes, Yves Levy, Michel Dy
Publikováno v:
The Journal of Immunology. 184:984-992
IL-17 is a potent effector cytokine involved in inflammatory response and antimicrobial defense. We report that SIV infection of rhesus macaques (RMs) results in the emergence of IL-17–expressing cells during the acute phase. This subpopulation app
Autor:
Stephanie Lay, Laurence Viollet, Marie-Christine Cumont, R Parker, Valérie Monceaux, Jérôme Estaquier, Bruno Hurtrel
Publikováno v:
Cell Death & Differentiation. 14:1747-1758
SIV-infected macaques exhibit distinct rates of progression to AIDS and despite significant increases in CD8+ T cells, immune cells fail to control and eradicate SIV in vivo. Here, we investigated the interplay between viral reservoir sites, CD8+ T-c
Autor:
Nathalie Schmitt, Nicole Israël, Gianfranco Pancino, Françoise Barré-Sinoussi, Marie-Christine Cumont, Marie-Thérèse Nugeyre, Daniel Scott-Algara
Publikováno v:
AIDS. 20:533-542
Objectives: Human thymus can be infected by HIV-1 with potential consequences on immune regeneration and homeostasis. We previously showed that CD4 thymocytes preferentially replicate CXCR4 tropic (X4) HIV-1 dependently on interleukin (IL)-7. Here we
Autor:
Valérie Monceaux, Bruno Hurtrel, Anne-Marie Aubertin, Jérôme Estaquier, Jean-Claude Ameisen, Marie-Christine Cumont
Publikováno v:
Journal of Medical Primatology. 29:127-135
Primary infection of rhesus macaques with pathogenic strains of simian immunodeficiency virus (SIV) leads to rapid and dynamic changes in both viral load and T cell counts in the peripheral blood. We have performed a sequential analysis of peripheral
Autor:
Emmanuel Khatissian, Valérie Monceaux, Marie-Christine Cumont, Bruno Hurtrel, Raphaël Ho Tsong Fang, Jérôme Estaquier
Publikováno v:
AIDS Research and Human Retroviruses. 19:267-274
We assessed the possible role in vivo CD4(+) CD8(+) T cells as a viral reservoir for simian immunodeficiency virus (SIV), in a macaque with 50% CD4(+) CD8(+) T cells in peripheral blood. During primary infection (day 14) of this rhesus macaque with t
Autor:
Marie-Paule Kieny, Anne-Marie Aubertin, Marie-Christine Cumont, Bruno Hurtrel, Emmanuel Khatissian, Valérie Monceaux
Publikováno v:
Journal of Virology. 75:1507-1515
Live attenuated simian immunodeficiency virus (SIV) is the most efficient vaccine yet developed in monkey models of human immunodeficiency virus infection. In all successful vaccine trials, attenuation was achieved by inactivating at least the nef ge
Autor:
Marion Desdouits, Thomas Papo, Franck Mortreux, Simona Ozden, Arnaud Lacour, Anne-Sophie Morin, Olivier Hermine, Olivier Gout, Thierry Maisonobe, Eric Wattel, Graham P. Taylor, Sandra Martin-Latil, Michel Huerre, Julien Haroche, Olivier Benveniste, Alexandra Desrames, Antônio Lúcio Teixeira, Marie-Christine Cumont, Antoine Gessain, Serge Herson, Gillian Butler-Browne, Marc Polivka, Fabien Zagnoli, Pascale Marcorelles, Jacqueline Mikol, Isabelle Pénisson-Besnier, Pierre-Emmanuel Ceccaldi, Olivier Cassar, Patrick Cherin, Zahir Amoura, Achille Aouba
Publikováno v:
Journal of Clinical Virology
Journal of Clinical Virology, 2013, 57 (1), pp.70-6. ⟨10.1016/j.jcv.2012.12.016⟩
Journal of Clinical Virology, Elsevier, 2013, 57 (1), pp.70-6. ⟨10.1016/j.jcv.2012.12.016⟩
Journal of Clinical Virology, Elsevier, 2013, 57 (1), pp.70-6. 〈10.1016/j.jcv.2012.12.016〉
Journal of Clinical Virology, 2013, 57 (1), pp.70-6. ⟨10.1016/j.jcv.2012.12.016⟩
Journal of Clinical Virology, Elsevier, 2013, 57 (1), pp.70-6. ⟨10.1016/j.jcv.2012.12.016⟩
Journal of Clinical Virology, Elsevier, 2013, 57 (1), pp.70-6. 〈10.1016/j.jcv.2012.12.016〉
Background The Human T-cell Leukemia Virus type 1 (HTLV-1) is the causative agent of several inflammatory diseases, including HTLV-1-associated inflammatory myopathies (HAIM). Little is known about the virological and immunological characteristics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3dce9838599144fc9e95d4f85a227f
https://hal-pasteur.archives-ouvertes.fr/pasteur-01370950
https://hal-pasteur.archives-ouvertes.fr/pasteur-01370950