Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marie-Chantal Simard"'
Autor:
Paul Jolicoeur, Nathalie Bouchard, Zaher Hanna, Vibhuti P. Dave, Pavel Chrobak, Joël Guertin, Marie-Chantal Simard, Thomas Ndolo
Publikováno v:
The Journal of Immunology. 185:3948-3959
The HIV-1 Nef protein is a major determinant of HIV-1 pathogenicity. It has been found to induce thymocyte depletion, but the mechanisms involved are not completely understood. Also, nothing is known about its effects on thymocyte selection. We used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b83e80e1e523b2f4e895c06df981b8
https://doi.org/10.4049/jimmunol.1001064
https://doi.org/10.4049/jimmunol.1001064
Autor:
Paul Jolicoeur, Frank Kirchhoff, Marie-Chantal Simard, Elena Priceputu, Chunyan Hu, Michael Schindler, Steffen Wildum, Zaher Hanna, Patrick Vincent
Publikováno v:
Journal of Virology. 81:4677-4693
We previously reported that the human immunodeficiency virus type 1 NL4-3 Nef is necessary and sufficient to induce a severe AIDS-like disease in transgenic (Tg) mice when the protein is expressed under the regulatory sequences of the human CD4 gene.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de170393cf20c5f33b6d3e677faae962
https://doi.org/10.1128/jvi.02691-06
https://doi.org/10.1128/jvi.02691-06
Publikováno v:
Journal of Virology. 76:3981-3995
In order to study the functions of simian immunodeficiency virus (SIV) Nef in vivo in a small-animal model, we constructed transgenic (Tg) mice expressing the SIVmac239nefgene in the natural target cells of the virus under the control of the human CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e29bc04544278a28e6fe1afe9fd5b5
https://doi.org/10.1128/jvi.76.8.3981-3995.2002
https://doi.org/10.1128/jvi.76.8.3981-3995.2002