Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie-Audrey Ines Kautzmann"'
Autor:
Nicolas G. Bazan, Silvia Gómez Alcalde, Marianne Schultzberg, Marie-Audrey Ines Kautzmann, Ceren Emre, Per Nilsson, Erik Hjorth, William C. Gordon, Bokkyoo Jun, Khanh Do
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-26 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Sustained brain chronic inflammation in Alzheimer’s disease (AD) includes glial cell activation, an increase in cytokines and chemokines, and lipid mediators (LMs), concomitant with decreased pro-homeostatic mediators. The inflammatory response at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22a13bc7f41770b4483c7070cc57fdf
https://doaj.org/article/ac96393851724d43b1cdd2767bc6342b
https://doaj.org/article/ac96393851724d43b1cdd2767bc6342b
Autor:
Nicolas G. Bazan, Marianne Schultzberg, Marie-Audrey Ines Kautzmann, Bokkyoo Jun, Maria Eriksdotter, Ying Wang, Erik Hjorth, Khanh Do
Background: Alzheimer's disease (AD) develops into dementia over a period of several years, during which subjective cognitive impairment (SCI) and mild cognitive impairment (MCI) are used as intermediary diagnoses of increasing severity. Chronic neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6d6bc8f4d0e83b6acd52a5ad697f30
https://doi.org/10.21203/rs.3.rs-1029034/v1
https://doi.org/10.21203/rs.3.rs-1029034/v1
Autor:
William C. Gordon, Khanh Do, Bokkyoo Jun, Rong Yang, Marie-Audrey Ines Kautzmann, Nicolas G. Bazan, Nicos A. Petasis, Robert Nshimiyimana
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This study uncovers biosynthetic pathway insufficiencies of prohomeostatic/neuroprotective mediators neuroprotectin D1 and elovanoids in the retina during early pathogenesis in transgenic Alzheimer’s disease 5xFAD mouse. These changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101320ef87d76fe99ba394de1071428a
https://doi.org/10.1073/pnas.1912959116
https://doi.org/10.1073/pnas.1912959116
Autor:
Aram Asatryan, Pranab K. Mukherjee, Khanh Do, Surjyadipta Bhattacharjee, Marie-Audrey Ines Kautzmann, Nicolas G. Bazan, Jorgelina M. Calandria, Bokkyoo Jun, William C. Gordon, Nicholas J. Maness, Nicos A. Petasis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
The pro-homeostatic lipid mediators elovanoids (ELVs) attenuate cell binding and entrance of the SARS-CoV-2 receptor-binding domain (RBD) as well as of the SARS-CoV-2 virus in human primary alveoli cells in culture. We uncovered that very-long-chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14db550ab5bb7bfb1fd2171958fc450c
https://doi.org/10.1038/s41598-021-91794-z
https://doi.org/10.1038/s41598-021-91794-z
Autor:
Khanh Do, Surjyadipta Bhattacharjee, Nicolas G. Bazan, Bokkyoo Jun, Jorgelina M. Calandria, William C. Gordon, Nicos A. Petasis, Pranab K. Mukherjee, Aram Asatryan, Marie-Audrey Ines Kautzmann
The pro-homeostatic lipid mediators elovanoids (ELVs) attenuate cell binding and entrance of the SARS-CoV-2 receptor-binding domain (RBD) in human primary alveoli cells in culture. We uncovered that very-long-chain polyunsaturated fatty acid precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c246e360a2478ae8e1bbacce5b7659f3
https://doi.org/10.21203/rs.3.rs-75121/v1
https://doi.org/10.21203/rs.3.rs-75121/v1
Autor:
Jessica Heap, Pranab K. Mukherjee, Nicolas G. Bazan, Nicos A. Petasis, Surjyadipta Bhattacharjee, Bokkyoo Jun, William C. Gordon, Rong Yang, Marie-Audrey Ines Kautzmann, Aram Asatryan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Docosahexaenoic acid (DHA, 22:6 n-3) is abundant in the retina and is enzymatically converted into pro-homeostatic docosanoids. The DHA- or eicosapentaenoic acid (EPA)-derived 26 carbon fatty acid is a substrate of elongase ELOVL4, which is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8228dfc85374630e1f3ed8e57508c05f
http://europepmc.org/articles/PMC5509689
http://europepmc.org/articles/PMC5509689
Autor:
Andre Obenaus, Rong Yang, Ludmila Belayev, Surjyadipta Bhattacharjee, Bokkyoo Jun, Nicolas G. Bazan, Larissa Khoutorova, Marie-Audrey Ines Kautzmann, Nicos A. Petasis, Hemant Menghani, Shawn J. Marcell, Jessica Heap
Publikováno v:
Science Advances
We report the discovery of a novel family of prohomeostatic and neuroprotective lipid mediators called elovanoids.
We report the characterization of a novel class of lipid mediators termed elovanoids (ELVs) (ELV-N32 and ELV-N34), which are dihyd
We report the characterization of a novel class of lipid mediators termed elovanoids (ELVs) (ELV-N32 and ELV-N34), which are dihyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4204b5996c2422046d302fbdcf8f5b8
https://pubmed.ncbi.nlm.nih.gov/28959727
https://pubmed.ncbi.nlm.nih.gov/28959727
Publikováno v:
Journal of Biological Chemistry. 286:28247-28255
Development and homeostasis require stringent spatiotemporal control of gene expression patterns that are established, to a large extent, by combinatorial action of transcription regulatory proteins. The bZIP transcription factor NRL (neural retina l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490cdb8649d6a884c6eaed1d699836f9
https://doi.org/10.1074/jbc.m111.257246
https://doi.org/10.1074/jbc.m111.257246
Autor:
Norimoto Gotoh, Marie-Audrey Ines Kautzmann, Avinash Hiriyanna, Jerome E. Roger, Anand Swaroop, Bo Chang, Rinki Ratnapriya, Debbie F. Cheng, Hong Hao
Leber congenital amaurosis (LCA) encompasses a set of early-onset blinding diseases that are characterized by vision loss, involuntary eye movement, and nonrecordable electroretinogram (ERG). At least 19 genes are associated with LCA, which is typica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521b54fbc2f2c1ed44c1cc0c313e79ec
https://europepmc.org/articles/PMC3904630/
https://europepmc.org/articles/PMC3904630/
Autor:
Sharada Prasad Yadav, Marie-Audrey Ines Kautzmann, Jacob Nellissery, Hyun-Jin Yang, Martin Seifert, Matthew Brooks, Anand Swaroop, Bernward Klocke, Hong Hao
Publikováno v:
Human molecular genetics. 23(8)
Phototransduction machinery in vertebrate photoreceptors is contained within the membrane discs of outer segments. Daily renewal of 10% of photoreceptor outer segments requires stringent control of gene expression. Rhodopsin constitutes over 90% of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767646a9091ce02d6e6282cd935dbeb4
https://pubmed.ncbi.nlm.nih.gov/24301678
https://pubmed.ncbi.nlm.nih.gov/24301678