Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marie-Annick Forget"'
Autor:
Marie-Annick Forget, Richard R. Desrosiers, Rolanda F. Del Maestro, Robert Moumdjian, Daniel Shedid, France Berthelet, Richard Béliveau
Publikováno v:
Clinical and Experimental Metastasis. 19:9-15
Astrocytic tumors are the most common human brain tumors. Establishment of tumor grade is a key determinant both in the choice of a therapeutic approach and in the prognosis. The diagnosis of astrocytic tumors is currently determined following histop
Publikováno v:
Shock. 5:167-183
Endothelins (ETs) are multifunctional isopeptides and their role in several pathophysiologies is slowly emerging. They are possible therapeutic targets in sepsis and other systemic inflammatory response syndromes (SIRS). In such conditions, elevated
Autor:
Bruno Battistini, Alain Fournier, Marie-Annick Forget, Pierre Sirois, Yvan Boulanger, Nathalie Lebel
Publikováno v:
Journal of Cardiovascular Pharmacology. 26:S107-110
Structurally reduced analogues of endothelin-1 (ET-1) were synthesized by linking via aminocaproic acid (Aca) the segment 3-11 of ET-1 to C-terminal fragments of various lengths [16-21, 17-21,..., 21]. Analogues were studied in their linear or cyclic
Autor:
Marie-Annick Forget, Mirjam M. P. Zegers, Jonathan Chernoff, Martin B.A. ter Beest, Steen H. Hansen, Keith E. Mostov
Publikováno v:
The EMBO journal. 22(16)
Wound healing in epithelia requires coordinated cell migration and proliferation regulated by signaling mechanisms that are poorly understood. Here we show that epithelial cells expressing constitutively active or kinase-dead mutants of the Rac/Cdc42
Autor:
Steen H. Hansen, William T. Arthur, Krister Wennerberg, Channing J. Der, Shawn M. Ellerbroek, Jeffrey Settleman, Marie-Annick Forget, Keith Burridge
Publikováno v:
University of Copenhagen
BACKGROUND: The Rnd proteins Rnd1, Rnd2, and Rnd3(RhoE) comprise a unique branch of Rho-family G-proteins that lack intrinsic GTPase activity, and consequently remain constitutively “active”. Prior studies have suggested that Rnd proteins play pi
The expression of rho proteins decreases with human brain tumor progression: potential tumor markers
Autor:
Marie-Annick, Forget, Richard R, Desrosiers, MaestroRolandaF, Del, Robert, Moumdjian, Daniel, Shedid, France, Berthelet, Richard, Béliveau
Publikováno v:
Clinicalexperimental metastasis. 19(1)
Astrocytic tumors are the most common human brain tumors. Establishment of tumor grade is a key determinant both in the choice of a therapeutic approach and in the prognosis. The diagnosis of astrocytic tumors is currently determined following histop
Publikováno v:
The Biochemical journal. 361(Pt 2)
The Rho GDP dissociation inhibitor (RhoGDI) regulates the activation-inactivation cycle of Rho small GTPases, such as Cdc42 and RhoA, by extracting them from the membrane. To study the roles of Mg(2+), phosphatidylinositol 4,5-bisphosphate (PIP(2)),
Autor:
L. J. D. O'donnell, Bruno Battistini, Marie-Annick Forget, Ralph R. S. H. Greaves, Michael J.G. Farthing
Publikováno v:
European journal of gastroenterologyhepatology. 12(11)
OBJECTIVES Pituitary adenylate cyclase-activating polypeptide (PACAP) is a recently identified member of the secretin/glucagon/vasoactive intestinal peptide (VIP) family. Like VIP, PACAP is largely inhibitory in the gastrointestinal tract. The aim of
Publikováno v:
Current Biology. (20):1606-1611
SummaryThe Rac GTPase regulates Rho signaling in a broad range of physiological settings and in oncogenic transformation [1–3]. Here, we report a novel mechanism by which crosstalk between Rac and Rho GTPases is achieved. Activated Rac1 binds direc