Výsledky vyhledávání - "Marie Zadinova"

Akademický článek

Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds

Autor: Renata Koníčková, Kateřina Vaňková, Jana Vaníková, Katerina Vánová, Lucie Muchová, Iva Subhanová, Marie Zadinová, Jaroslav Zelenka, Ales Dvořák, Michal Kolář, Hynek Strnad, Silvie Rimpelová, Tomas Ruml, Ronald J. Wong, Libor Vítek

Publikováno v: Annals of Hepatology, Vol 13, Iss 2, Pp 273-283 (2014)

Spirulina platensis is a blue-green alga used as a dietary supplement because of its hypocholesterolemic properties. Among other bioactive substances, it is also rich in tetrapyrrolic compounds closely related to bilirubin molecule, a potent antioxid

Externí odkaz: https://doaj.org/article/27fb99bbdf824f9f9ac1cb2c7b0e5c4e

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Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues

Autor: Olga Janoušková, Richard Hoogenboom, Marie Zadinova, Maarten Vergaelen, Martin Hruby, Bart Verbraeken, Ondrej Sedlacek, Jana Mattova, Bryn D. Monnery, Anita Höcherl, Jan Kučka, Jiri Panek

Publikováno v: Biomaterials. 146

We designed and synthesized a new delivery system for the anticancer drug doxorubicin based on a biocompatible hydrophilic poly(2-ethyl-2-oxazoline) (PEtOx) carrier with linear architecture and narrow molar mass distribution. The drug is connected to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989fefdf71137aab3f568395fee10df5
https://pubmed.ncbi.nlm.nih.gov/28892751

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Multistage-targeted pH-responsive polymer conjugate of Auger electron emitter: Optimized design and in vivo activity

Autor: Pavla Pouckova, Jana Mattova, Marie Zadinova, Martin Studenovsky, Martin Hruby, Ondrej Sedlacek, Martin Parizek, Jan Kučka

Publikováno v: European Journal of Pharmaceutical Sciences. 63:216-225

Auger electrons-emitting radioisotopes (such as iodine-125) are a potentially effective cancer treatment. They are extremely biologically effective, but only within a short range (nanometers). Their use as an effective cancer therapy requires that th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9675cb037d74e0ed9eb1f5fac4bd5108
https://doi.org/10.1016/j.ejps.2014.07.012

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Optimum modality for photodynamic therapy of tumors: gels containing liposomes with hydrophobic photosensitizers

Autor: Milos Nekvasil, Petr Ježek, Marie Zadinova, Ludmila Tahotná, Markéta Žáčková, Pavla Pouckova

Publikováno v: Drug Development Research. 68:235-252

Photodynamic therapy (PDT) has entered an era of clinical acceptance; however, for its wider use, including drug formulations for topical applications, it must have a rapid effect and be free of skin-photosensitization effects. Preclinical studies of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8963ecc5f22574723b84c823329a148f
https://doi.org/10.1002/ddr.20184

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Dual role of host Par2 in a murine model of spontaneous metastatic B16 melanoma

Autor: Tomas, Olejar, David, Vetvicka, Marie, Zadinova, Pavla, Pouckova, Jaromir, Kukal, Petr, Jezek, Radoslav, Matej

Publikováno v: Anticancer research. 34(7)

We investigated differences of metastatic spread of normal proteinase-activated receptor-2 (Par2+/+) melanoma B16 in Par2-/- (knock-out) animals compared to C57Bl6 mice.Nine knock-out mice B6.Cg-F2rl1tm1Mslb/J (Par2-/-) and nine C57Bl6/J controls wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f71621f3cf56859f0b761488bd49a20b
https://pubmed.ncbi.nlm.nih.gov/24982362

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Novel topical photodynamic therapy of prostate carcinoma using hydroxy-aluminum phthalocyanine entrapped in liposomes

Autor: Karol, Sutoris, Jan, Rakusan, Marie, Karaskova, Jana, Mattova, Jiri, Benes, Milos, Nekvasil, Petr, Jezek, Marie, Zadinova, Pavla, Pouckova, David, Vetvicka

Publikováno v: Anticancer research. 33(4)

Clinically-approved anticancer photodynamic therapy (PDT) is now extensively studied for various cancer diagnoses. We focused on the treatment efficacy of topical administration of hydroxy-aluminum phthalocyanine (AlOH-PC) entrapped in liposomes agai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e3ca49617ecae9b1b6b350ecc7f6539
https://pubmed.ncbi.nlm.nih.gov/23564798

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