Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Marie Westerlund"'
Autor:
Caroline Ran, Karin Wirdefeldt, Lovisa Brodin, Mehrafarin Ramezani, Marie Westerlund, Fengqing Xiang, Anna Anvret, Thomas Willows, Olof Sydow, Anders Johansson, Dagmar Galter, Per Svenningsson, Andrea Carmine Belin
Publikováno v:
Parkinson's Disease, Vol 2017 (2017)
Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. NRF2 has therefore been hypothesized to confer protection against Parkinson’s disease and so
Externí odkaz:
https://doaj.org/article/e7dbcf9dd3ef4e7a865416f7baddc886
Autor:
David Ramonet, João Paulo L Daher, Brian M Lin, Klodjan Stafa, Jaekwang Kim, Rebecca Banerjee, Marie Westerlund, Olga Pletnikova, Liliane Glauser, Lichuan Yang, Ying Liu, Deborah A Swing, M Flint Beal, Juan C Troncoso, J Michael McCaffery, Nancy A Jenkins, Neal G Copeland, Dagmar Galter, Bobby Thomas, Michael K Lee, Ted M Dawson, Valina L Dawson, Darren J Moore
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18568 (2011)
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset, autosomal dominant familial Parkinson's disease (PD) and also contribute to idiopathic PD. LRRK2 mutations represent the most common cause of PD with clinical and neurochemi
Externí odkaz:
https://doaj.org/article/01d6a4bc1a0c4047be5141533aeb099b
Autor:
Anna Anvret, Caroline Ran, Marie Westerlund, Ann-Christin Thelander, Olof Sydow, Charlotta Lind, Anna Håkansson, Hans Nissbrandt, Dagmar Galter, Andrea Carmine Belin
Publikováno v:
Parkinson's Disease, Vol 2010 (2010)
Genes important for mitochondrial function have been implicated in Parkinson's disease (PD). Mitochondrial translation initiation factor 3 (MTIF3) is a nuclear encoded protein required for the initiation of complex formation on mitochondrial ribosome
Externí odkaz:
https://doaj.org/article/f79728a3ff9245f7aaf5035c75c3e2bc
Autor:
Caroline Ran, Lovisa Brodin, Sandra Gellhaar, Marie Westerlund, Camilla Fardell, Hans Nissbrandt, Peter Söderkvist, Olof Sydow, Ioanna Markaki, Ellen Hertz, Karin Wirdefeldt, Per Svenningsson
INTRODUCTION: Genetic variants in the Beta-glucocerebrosidase gene (GBA1) is a known risk factor for Parkinson's disease. The GBA1 mutations L444P, N370S and many other have been shown to associate with the disease in populations with diverse backgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665504aec60bfb052906cabe85ae0d2f
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-193497
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-193497
Autor:
Anna Anvret, Olof Sydow, Andrea Carmine Belin, L.-A. Brodin, Marie Westerlund, Karin Wirdefeldt, Anders Johansson, Per Svenningsson, Fengqing Xiang, Thomas Willows, Caroline Ran, Mehrafarin Ramezani, Dagmar Galter
Publikováno v:
Parkinson's Disease, Vol 2017 (2017)
Parkinson's Disease
Parkinson's Disease
Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. NRF2 has therefore been hypothesized to confer protection against Parkinson’s disease and so
Autor:
Anna Håkansson, Olof Sydow, Andrea Carmine Belin, Peter Söderkvist, Marie Westerlund, Thomas Willows, Anna Anvret, Hans Nissbrandt, Silvia Paddock, Caroline Ran, Ahmad Ahmadi, Dagmar Galter, Maria Anvret, Nil Dizdar
Publikováno v:
Neuroscience Letters. 522:30-35
Pesticide exposure has been suggested to increase the risk to develop Parkinson's disease (PD). The arylesterase paraoxonase 1 (PON1) is mainly expressed in the liver and hydrolyzes organophosphates such as pesticides. The polymorphism Leu54Met (rs85
Autor:
Andrea Carmine Belin, Thomas Willows, Olof Sydow, Caroline Ran, Marie Westerlund, Lars Olson, Dagmar Galter, Anna Anvret
Publikováno v:
The Open Neurology Journal
MIRO1 and MIRO2 (mitochondrial Ras homolog gene family, member T1 and T2) also referred to as RHOT1 and RHOT2, belong to the mitochondrial Rho GTPase family and are involved in axonal transport of mitochondria in neurons. Because mitochondrial dysfun
Autor:
Thomas Willows, Olof Sydow, Marie Westerlund, Caroline Ran, Anna Håkansson, Andrea Carmine Belin, Jeff G. Blackinton, Anna Anvret, Hans Nissbrandt
Publikováno v:
The Open Neurology Journal
Mutations in the PARK7 gene, DJ-1, have been reported to cause early-onset and familial Parkinson’s disease (PD). The function of DJ-1 and how it contributes to the development of the disease is not clear today, but several studies report that DJ-1
Autor:
Charlotta Lind, Olof Sydow, Thomas Willows, Marie Westerlund, Dagmar Galter, Andrea Carmine Belin, Anna Anvret
Publikováno v:
Neuroscience Letters. 485:117-120
DNA polymerase gamma (POLG1) is coding for the catalytic subunit of the heterotrimeric mitochondrial DNA polymerase and involved in replication and repair of mitochondrial DNA. In addition to its 5' to 3' polymerase activity, POLG1 has a 3' to 5' exo
Publikováno v:
Progress in Neurobiology. 90:146-156
Parkinson's disease was long considered a non-hereditary disorder. Despite extensive research trying to find environmental risk factors for the disease, genetic variants now stand out as the major causative factor. Since a number of genes have been i