Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie Weiel"'
Autor:
Oskar Taubert, Fabrice von der Lehr, Alina Bazarova, Christian Faber, Philipp Knechtges, Marie Weiel, Charlotte Debus, Daniel Coquelin, Achim Basermann, Achim Streit, Stefan Kesselheim, Markus Götz, Alexander Schug
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract On the path to full understanding of the structure-function relationship or even design of RNA, structure prediction would offer an intriguing complement to experimental efforts. Any deep learning on RNA structure, however, is hampered by th
Externí odkaz:
https://doaj.org/article/d536d84aae0f4245a6e3998c83d5238a
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242072 (2020)
Proteins are complex biomolecules which perform critical tasks in living organisms. Knowledge of a protein's structure is essential for understanding its physiological function in detail. Despite the incredible progress in experimental techniques, pr
Externí odkaz:
https://doaj.org/article/afc4620d22a7437fa5d6f119309f68ac
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 3, p e1006900 (2019)
The fundamental aim of structural analyses in biophysics is to reveal a mutual relation between a molecule's dynamic structure and its physiological function. Small-angle X-ray scattering (SAXS) is an experimental technique for structural characteriz
Externí odkaz:
https://doaj.org/article/3446b919f31949fd83e5622c78299ba4
Autor:
Oskar Taubert, Marie Weiel, Daniel Coquelin, Anis Farshian, Charlotte Debus, Alexander Schug, Achim Streit, Markus Götz
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783031320408
We present Propulate, an evolutionary optimization algorithm and software package for global optimization and in particular hyperparameter search. For efficient use of HPC resources, Propulate omits the synchronization after each generation as done i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7f0e0ec11cedea07ff74f88108ce2a
https://doi.org/10.1007/978-3-031-32041-5_6
https://doi.org/10.1007/978-3-031-32041-5_6
Publikováno v:
Nature machine intelligence, 3 (8), 727–734
Nature machine intelligence 3(8), 727-734 (2021). doi:10.1038/s42256-021-00366-3
Nature machine intelligence 3(8), 727-734 (2021). doi:10.1038/s42256-021-00366-3
Molecular simulations are a powerful tool to complement and interpret ambiguous experimental data on biomolecules to obtain structural models. Such data-assisted simulations often rely on parameters, the choice of which is highly non-trivial and cruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebff85cdc7e5ab566dff17c54d720460
https://doi.org/10.1038/s42256-021-00366-3
https://doi.org/10.1038/s42256-021-00366-3
Publikováno v:
Journal of molecular biology 433(7), 166859-(2021). doi:10.1016/j.jmb.2021.166859
Journal of Molecular Biology, 433 (7), Art.-Nr.: 166859
Journal of Molecular Biology, 433 (7), Art.-Nr.: 166859
Icosahedral viral capsids assemble with high fidelity from a large number of identical buildings blocks. The mechanisms that enable individual capsid proteins to form stable oligomeric units (capsomers) while affording structural adaptability require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b235b73efcc1a1f46b71639a0e49c465
https://pubmed.ncbi.nlm.nih.gov/33539884
https://pubmed.ncbi.nlm.nih.gov/33539884
Proteins are complex biomolecules which perform critical tasks in living organisms. Knowledge of a protein’s structure is essential for understanding its physiological function in detail. Despite the incredible progress in experimental techniques,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5c7ffbfaea9ab6584cd5d5d18714f4
Publikováno v:
Israel journal of chemistry, 60 (7), 725–734
Israel journal of chemistry 60(7), 725-734 (2020). doi:10.1002/ijch.202000007
Israel journal of chemistry 60(7), 725-734 (2020). doi:10.1002/ijch.202000007
Structural analyses in biophysics aim at revealing a relationship between a molecule's dynamic structure and its physiological function. Förster resonance energy transfer (FRET) and small-angle X-ray scattering (SAXS) are complementary experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6551ae36f5d87f3043a0562076b218b5
https://publikationen.bibliothek.kit.edu/1000122185
https://publikationen.bibliothek.kit.edu/1000122185
We introduce an evolutionary metacommunity of multitrophic food webs on several habitats coupled by migration. In contrast to previous studies that focus either on evolutionary or on spatial aspects, we include both and investigate the interplay betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5c7291e88e6b5e93777220ac1536b5
http://arxiv.org/abs/1409.3065
http://arxiv.org/abs/1409.3065
Publikováno v:
The European physical journal. E, Soft matter. 35(10)
We investigate the dynamical behavior of simple networks, namely loops with an additional internal regulating connection. Continuous dynamics for mRNA and protein concentrations is compared to a Boolean model for gene activity. Using a generalized me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2bbf0dffff49ee4b33b786b0574c2f
https://pubmed.ncbi.nlm.nih.gov/23096153
https://pubmed.ncbi.nlm.nih.gov/23096153