Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Marie W. Wooten"'
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 2, Pp 302-310 (2009)
Recently we reported that declined SQSTM1/p62 expression in Alzheimer disease brain was age-correlated with oxidative damage to the p62 promoter. The objective of this study was to examine whether oxidative damage to the p62 promoter is common to DNA
Externí odkaz:
https://doaj.org/article/2efac4d8f78242bb9907e5f95dcf0ae6
Autor:
Michael G. Paine, Marie W. Wooten
Publikováno v:
Impulse: The Premier Undergraduate Neuroscience Journal, p 1 (2006)
The ubiquitin-proteasome system (UPS) is the pathway for degradation of nuclear and cytosolic proteins that are aged, damaged, or misfolded. Malfunctions in the UPS have been implicated in a wide variety of neurodegenerative diseases. Some proteins,
Externí odkaz:
https://doaj.org/article/aa2ce476b76f45c8a7f95e2054d9c7b4
Autor:
Jin Yan, Michael Lamar Seibenhener, Luis Calderilla-Barbosa, Maria-Theresa Diaz-Meco, Jorge Moscat, Jianxiong Jiang, Marie W Wooten, Michael C Wooten
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76016 (2013)
Protein aggregates can form in the cytoplasm of the cell and are accumulated at aggresomes localized to the microtubule organizing center (MTOC) where they are subsequently degraded by autophagy. In this process, aggregates are engulfed into autophag
Externí odkaz:
https://doaj.org/article/c7848073d6e94c04b38d2691bed6fb82
Autor:
Michael C. Wooten, M. Lamar Seibenhener, Maria-Theresa Diaz-Meco, Jorge Moscat, Marie W. Wooten, Yifeng Du
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833:452-459
As a signaling scaffold, p62/sequestosome (p62/SQSTM1) plays important roles in cell signaling and degradation of misfolded proteins. While localization of p62 to mitochondria has been reported, a description of its function once there, remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf220601624fe2323df72f3dfbbc9670
https://doi.org/10.1016/j.bbamcr.2012.11.004
https://doi.org/10.1016/j.bbamcr.2012.11.004
Autor:
Daydrie Hague, Toni Alexander, Marie W. Wooten, Alice E. Smith, Daniel Svyantek, Overtoun Jenda, Donna L. Sollie
Publikováno v:
The International Journal of Diversity in Organizations, Communities, and Nations: Annual Review. 10:37-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098d5d11022f980f8e27a26fff557f57
https://doi.org/10.18848/1447-9532/cgp/v10i05/39911
https://doi.org/10.18848/1447-9532/cgp/v10i05/39911
Autor:
Haining Zhu, Weisi Fu, Ping Shi, Marie W. Wooten, Jiayu Zhang, Jozsef Gal, Renee Kilty, Anna-Lena Ström, David M. Kwinter
Publikováno v:
Journal of Neurochemistry. 111:1062-1073
The p62/sequestosome 1 protein has been identified as a component of pathological protein inclusions in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). P62 has also been implicated in autophagy, a process of mass degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f87e710c71e0f804bda9bb0a774fdf4
https://doi.org/10.1111/j.1471-4159.2009.06388.x
https://doi.org/10.1111/j.1471-4159.2009.06388.x
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 2, Pp 302-310 (2009)
Recently we reported that declined SQSTM1/p62 expression in Alzheimer disease brain was age-correlated with oxidative damage to the p62 promoter. The objective of this study was to examine whether oxidative damage to the p62 promoter is common to DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20a078a155f80dd409b1afceb423323
https://doi.org/10.1016/j.nbd.2009.05.015
https://doi.org/10.1016/j.nbd.2009.05.015
Autor:
Marie W. Wooten, Trafina Jadhav
Publikováno v:
Journal of Proteomics & Bioinformatics. :316-333
It has been more than 30 years since the initial report of the discovery of ubiquitin as an 8.5 kDa protein of unknown function expressed universally in living cells. And still, protein modification by covalent conjugation of the ubiquitin molecule i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1221a960a6f3a272bd962ec6fd86dcd9
https://doi.org/10.4172/jpb.1000091
https://doi.org/10.4172/jpb.1000091
Publikováno v:
Free Radical Biology and Medicine. 46:492-501
The absence of the p62 gene in mouse brain leads to biochemical and cognitive deficits that resemble Alzheimer disease (AD). In this context, the objective of this study was to examine the relationship between age-induced oxidative damage to the p62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5d9614bd2b8f287c873782d4c99a1c
https://doi.org/10.1016/j.freeradbiomed.2008.11.003
https://doi.org/10.1016/j.freeradbiomed.2008.11.003
Publikováno v:
Biochemical and Biophysical Research Communications. 374:33-37
The scaffold protein p62 is involved in internalization and trafficking of TrkA. The receptor is deubiquitinated by the proteasomes prior to degradation by lysosomes. Here we demonstrate that p62 serves as a shuttling protein for interaction of ubiqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e546b9de6eb8e0457f1dd3088a76fc1b
https://doi.org/10.1016/j.bbrc.2008.06.082
https://doi.org/10.1016/j.bbrc.2008.06.082