Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

Autor: Philippe E. Mangeot, Valérie Risson, Floriane Fusil, Aline Marnef, Emilie Laurent, Juliana Blin, Virginie Mournetas, Emmanuelle Massouridès, Thibault J. M. Sohier, Antoine Corbin, Fabien Aubé, Marie Teixeira, Christian Pinset, Laurent Schaeffer, Gaëlle Legube, François-Loïc Cosset, Els Verhoeyen, Théophile Ohlmann, Emiliano P. Ricci

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

A current challenge in genome editing is delivering Cas9 and sgRNA into target cells. Here the authors engineer a delivery system based on murine leukemia virus-like particles loaded with Cas9-sgRNA ribonucleoproteins to induce efficient genome editi

Externí odkaz: https://doaj.org/article/0bd13889c5db4e0ba26c33892287ae45

Potencialidades e limitações da Rede Sentinela para o aperfeiçoamento do monitoramento pós-comercialização/pós-uso de produtos sob vigilância sanitária adotado pela Anvisa

Autor: Mota, Daniel Marques, Cammarota, Dolly Milena Ovando Talavera, Leitão, Leonardo Oliveira, Teixeira, Ana Paula Coelho Penna, Barreiros, Viviane Vilela Marques, Rodrigues Gomes, Fabiana, Surita, Lucia Eichenberg, Gomes, Suzie Marie Teixeira

Publikováno v: Health Surveillance under Debate: Society, Science & Technology ; Vol. 10 No. 4 (2022): November-Commemorative Edition: 10 Years of Visa in Debate; 20-31
Vigilancia en Salud en Debate: Sociedad, Ciencia y Tecnología; Vol. 10 Núm. 4 (2022): Noviembre-Edición Conmemorativa: 10 Años de Visa en Debate; 20-31
Vigil Sanit Debate, Rio de Janeiro; v. 10 n. 4 (2022): Novembro-Edição comemorativa: 10 anos da Visa em Debate; 20-31
Vigilância Sanitária em Debate
Fundação Oswaldo Cruz (Fiocruz)
instacron:FIOCRUZ

Introduction: Hospitals are essential for the universal coverage of any health system, as well as sources of valuable information on adverse events and technical complaints of products subjects to health surveillance. Objective: To identify the poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::341a832640a36691e16dc6c0be418b19
https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/2089

Chemical treatments of flax fibers - Control of the diffusion of molecules into the fiber structure

Autor: Marie Teixeira, Jean-Claude Roux, Ichem Chala, Sophie Rouif, Claire Longuet, Belkacem Otazaghine, Rodolphe Sonnier, Sana Ben Abdallah

Publikováno v: Industrial Crops and Products
Industrial Crops and Products, Elsevier, 2019, 132, pp.430-439. ⟨10.1016/j.indcrop.2019.02.041⟩

International audience; This study concerns the control of the diffusion of molecules and macromolecules in the structure of flax fibers during the impregnation step of a radiation grafting procedure. In this work we essentially focused on the impact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40298f91b20fc9daab30b40191135fa
https://hal.archives-ouvertes.fr/hal-02424967

Molecular investigation of isolates from a multistate polymicrobial outbreak associated with contaminated total parenteral nutrition in Brazil

Autor: Pillonetto, Marcelo, Arend, Lavinia Nery Villa Stangler, Gomes, Suzie Marie Teixeira, Oliveira, Marluce Aparecida Assunção, Timm, Loeci Natalina, Martins, Andreza Francisco, Barth, Afonso Luis, Mazzetti, Alana, Hersemann, Lena, Smits, Theo H. M., Mira, Marcelo Távora, Rezzonico, Fabio

Publikováno v: Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS

Background: Between November 2013 and June 2014, 56 cases of bacteremia (15 deaths) associated with the use of Total Parenteral Nutrition (TPN) and/or calcium gluconate (CG) were reported in four Brazilian states. Methods: We analyzed 73 bacterial is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::2482325973f50c6069e292268863fdf5

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors

Autor: Denise Aubert, Martine Tomkowiak, Jean-Louis Thoumas, Charles-Antoine Coupet, Didier Nègre, Marie Teixeira, Molly Brunner, Raffaella Ghittoni, François-Loïc Cosset, Jacqueline Marvel, Yann Leverrier, Judit Szécsi, Bariza Blanquier, Els Verhoeyen

Publikováno v: genesis. 51:193-200

Immune tolerance to self-antigens is a complex process that utilizes multiple mechanisms working in concert to maintain homeostasis and prevent autoimmunity. Considerable progress in deciphering the mechanisms controlling the activation or deletion o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0c2ecdea1bd37f275a0fcf520011978
https://doi.org/10.1002/dvg.22364