Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Marie Stiborova"'
Autor:
Vladislav Strmiska, Petr Michalek, Zuzana Lackova, Roman Guran, Sona Krizkova, Lucie Vanickova, Ondrej Zitka, Marie Stiborova, Tomas Eckschlager, Borivoj Klejdus, Dalibor Pacik, Eliska Tvrdikova, Claudia Keil, Hajo Haase, Vojtech Adam, Zbynek Heger
Publikováno v:
Molecular Oncology, Vol 13, Iss 5, Pp 1002-1017 (2019)
DNA hypermethylation is one of the most common epigenetic modifications in prostate cancer (PCa). Several studies have delineated sarcosine as a PCa oncometabolite that increases the migration of malignant prostate cells while decreasing their doubli
Externí odkaz:
https://doaj.org/article/04f0e5a202ed485ea5b906c03279d789
Autor:
David H. Phillips, Heinz H. Schmeiser, C. Roland Wolf, Bruno Sopko, Vaclav Martinek, Eva Frei, Christian A. Bieler, Martin R. Osborne, Colin J. Henderson, Marie Stiborova, Volker M. Arlt
3-Nitrobenzanthrone (3-nitro-7H-benz[de]anthracen-7-one, 3-NBA) is a potent mutagen and suspected human carcinogen identified in diesel exhaust and air pollution. We compared the ability of human hepatic cytosolic samples to catalyze DNA adduct forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e75705da18b3aba5471340200973db7
https://doi.org/10.1158/0008-5472.c.6494375
https://doi.org/10.1158/0008-5472.c.6494375
Autor:
David H. Phillips, Heinz H. Schmeiser, C. Roland Wolf, Bruno Sopko, Vaclav Martinek, Eva Frei, Christian A. Bieler, Martin R. Osborne, Colin J. Henderson, Marie Stiborova, Volker M. Arlt
12 Tables, 3 Figure from Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c8317ec30a6b0fe84ee1b09bc35097
https://doi.org/10.1158/0008-5472.22364816.v1
https://doi.org/10.1158/0008-5472.22364816.v1
Autor:
Jaromir Gumulec, Michaela Fojtu, Martina Raudenska, Marketa Sztalmachova, Anna Skotakova, Jana Vlachova, Sylvie Skalickova, Lukas Nejdl, Pavel Kopel, Lucia Knopfova, Vojtech Adam, Rene Kizek, Marie Stiborova, Petr Babula, Michal Masarik
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 22960-22977 (2014)
Doxorubicin is an effective chemotherapeutic drug, however, its toxicity is a significant limitation in therapy. Encapsulation of doxorubicin inside liposomes or ferritin cages decreases cardiotoxicity while maintaining anticancer potency. We synthes
Externí odkaz:
https://doaj.org/article/83fba333ebf64f6ca510cf93e401855f
Publikováno v:
Sensors, Vol 14, Iss 12, Pp 22982-22997 (2014)
The requirements for early diagnostics as well as effective treatment of cancer diseases have increased the pressure on development of efficient methods for targeted drug delivery as well as imaging of the treatment success. One of the most recent ap
Externí odkaz:
https://doaj.org/article/78223966f3a34148bf3df5347575f2ee
Autor:
Martina Raudenska, Ludmila Krejcova, Lukas Richtera, Zbynek Heger, Jan Hrabeta, Tomas Eckschlager, Marie Stiborova, Vojtech Adam, Monika Kratochvilova, Michal Masarik, Jaromir Gumulec
Publikováno v:
Tumor Biology, Vol 39 (2017)
Neuroblastoma represents a malignancy of the sympathetic nervous system characteristic by biological heterogeneity. Thus, chemotherapy exhibits only low effectivity in curing high-risk forms. Previous studies revealed the cytotoxic potential of valpr
Externí odkaz:
https://doaj.org/article/b0971fb99a644becbfca7f7df620ebb9
Autor:
Zbynek Heger, Natalia Cernei, Jiri Kudr, Jaromir Gumulec, Iva Blazkova, Ondrej Zitka, Tomas Eckschlager, Marie Stiborova, Vojtech Adam, Rene Kizek
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 11, Pp 21629-21646 (2013)
Doxorubicin is a commonly used antineoplastic agent in the treatment of many types of cancer. Little is known about the interactions of doxorubicin with cardiac biomolecules. Serious cardiotoxicity including dilated cardiomyopathy often resulting in
Externí odkaz:
https://doaj.org/article/4abc32d35e6f49c18452703f3f434e98
Autor:
Rene Kizek, Vojtech Adam, Marie Stiborova, Tomas Eckschlager, Petr Babula, Michal Masarik, Ondrej Zitka, Jaromir Gumulec, Natalia Cernei, Zbynek Heger
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 13893-13908 (2013)
Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that fact, there is great interest
Externí odkaz:
https://doaj.org/article/cdddc0814d6141c882d4f38a2eb680e0
Autor:
Vojtech Adam, Marie Stiborova, Rene Kizek, Tomas Eckschlager, Marketa Vaculovicova, Pavel Kopel, Maja Stanisavljevic, Iva Blazkova, Hoai Viet Nguyen, Simona Dostalova
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 13391-13402 (2013)
Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was
Externí odkaz:
https://doaj.org/article/870b6f208071405281692bffb620bf93
Autor:
Rene Kizek, Marie Stiborova, Vojtech Adam, Tomas Eckschlager, Michal Masarik, Ondrej Zitka, Jaromir Gumulec, Branislav Ruttkay-Nedecky, Lukas Nejdl
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 3, Pp 6044-6066 (2013)
Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause the molecule to become highly reactive. The free radicals are also known to play a dual role in biological systems, as they
Externí odkaz:
https://doaj.org/article/337893c871c648488c2ef7dcf8c1a94c